110236-78-7

• 常用中文名：5-amino-1-cyclopropyl-6,8-difluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid
• 常用英文名：5-amino-1-cyclopropyl-6,8-difluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid
• CAS号：110236-78-7
• 分子式：C₁₇H₁₈F₂N₄O₃
• 分子量：364.34700
• 发布时间：2017-03-15 08:09:45
• 更新时间：2024-01-09 11:32:45

名称

• 英文名: 5-amino-1-cyclopropyl-6,8-difluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid
• 英文别名: 3-Quinolinecarboxylic acid,1,4-dihydro-5-amino-1-cyclopropyl-6,8-difluoro-4-oxo-7-(1-piperazinyl); 5-amino-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid; 3-Quinolinecarboxylicacid,5-amino-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl); 5-amino-1-cyclopropyl-6,8-difluoro-7-(1-piperazinyl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid

物化性质

• 密度: 1.562g/cm3
• 沸点: 652.7ºC at 760mmHg
• 分子式: C₁₇H₁₈F₂N₄O₃
• 分子量: 364.34700
• 闪点: 348.5ºC
• 精确质量: 364.13500
• PSA: 100.59000
• LogP: 2.27960
• 蒸汽压: 6.35E-18mmHg at 25°C
• 折射率: 1.673

合成路线

110-85-0 103772-14-1 ~75% 110236-78-7

文献：Domagala, John M.; Hagen, Susan E.; Heifetz, Carl L.; Hutt, Marland P.; Mich, Thomas F.; et al. Journal of Medicinal Chemistry, 1988 , vol. 31, p. 503 - 506

107564-02-3 ~% 110236-78-7

文献：Miyamoto, Teruyuki; Matsumoto, Jun-ichi; Chiba, Katsumi; Egawa, Hiroshi; Shibamori, Koh-ichiro; et al. Journal of Medicinal Chemistry, 1990 , vol. 33, # 6 p. 1645 - 1656

110872-04-3 ~% 110236-78-7

文献：Miyamoto, Teruyuki; Matsumoto, Jun-ichi; Chiba, Katsumi; Egawa, Hiroshi; Shibamori, Koh-ichiro; et al. Journal of Medicinal Chemistry, 1990 , vol. 33, # 6 p. 1645 - 1656

103772-12-9 ~% 110236-78-7

文献：Domagala, John M.; Hagen, Susan E.; Heifetz, Carl L.; Hutt, Marland P.; Mich, Thomas F.; et al. Journal of Medicinal Chemistry, 1988 , vol. 31, p. 503 - 506

103772-13-0 ~% 110236-78-7

文献：Miyamoto, Teruyuki; Matsumoto, Jun-ichi; Chiba, Katsumi; Egawa, Hiroshi; Shibamori, Koh-ichiro; et al. Journal of Medicinal Chemistry, 1990 , vol. 33, # 6 p. 1645 - 1656

上下游产品

上游产品  6
110-85-0 103772-14-1 107564-02-3 110872-04-3
103772-12-9 103772-13-0
下游产品  0