5-amino-1-cyclopropyl-6,8-difluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid

• 常用名: 5-amino-1-cyclopropyl-6,8-difluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid
• 英文名: 5-amino-1-cyclopropyl-6,8-difluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid
• CAS号: 110236-78-7
• 分子量: 364.34700
• 密度: 1.562g/cm3
• 沸点: 652.7ºC at 760mmHg
• 分子式: C₁₇H₁₈F₂N₄O₃
• 熔点: N/A
• 闪点: 348.5ºC

名称

• 英文名: 5-amino-1-cyclopropyl-6,8-difluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid

物理化学性质

• 密度: 1.562g/cm3
• 沸点: 652.7ºC at 760mmHg
• 分子式: C₁₇H₁₈F₂N₄O₃
• 分子量: 364.34700
• 闪点: 348.5ºC
• 精确质量: 364.13500
• PSA: 100.59000
• LogP: 2.27960
• InChIKey: LMOANZHDQSNEII-UHFFFAOYSA-N
• SMILES: Nc1c(F)c(N2CCNCC2)c(F)c2c1c(=O)c(C(=O)O)cn2C1CC1
• 蒸汽压: 6.35E-18mmHg at 25°C
• 折射率: 1.673

靶点实验

查看更多实验

实验名称：Antibacterial activity was determined against gram positive organism, Streptococcus f... 来源：ChEMBL 靶标：Enterococcus faecalis External Id：CHEMBL799853

实验名称：In vitro antibacterial activity against Escherichia coli NIHJ JC-2 来源：ChEMBL 靶标：Escherichia coli External Id：CHEMBL679695

实验名称：Antibacterial activity was determined against gram negative organism, Pseudomonas aer... 来源：ChEMBL 靶标：Pseudomonas aeruginosa External Id：CHEMBL754839

实验名称：In vitro antibacterial activity against Escherichia coli P-5101 来源：ChEMBL 靶标：Escherichia coli External Id：CHEMBL679696

实验名称：In vitro antibacterial activity against glucose nonfermenter Moraxella bovis P-7101 来源：ChEMBL 靶标：Moraxella bovis External Id：CHEMBL731583

实验名称：In vivo protection against gram-positive Escherichia coli vogel in mouse after oral a... 来源：ChEMBL 靶标：Escherichia coli External Id：CHEMBL676461

实验名称：Oral efficacy against Pseudomonas aeruginosa 12 on Systemic Infections in Mice 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL721369

实验名称：In vivo protection against gram-positive Escherichia coli vogel in mouse after subcut... 来源：ChEMBL 靶标：Escherichia coli External Id：CHEMBL676304

实验名称：Oral efficacy against Streptococcus pyogenes A65 on Systemic Infections in Mice 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL721372

实验名称：The in vivo potency was determined in female charles river CD-1 mice infected with Es... 来源：ChEMBL 靶标：Escherichia coli External Id：CHEMBL674838

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英文别名

• 3-Quinolinecarboxylic acid,1,4-dihydro-5-amino-1-cyclopropyl-6,8-difluoro-4-oxo-7-(1-piperazinyl)
• 5-amino-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
• 3-Quinolinecarboxylicacid,5-amino-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)
• 5-amino-1-cyclopropyl-6,8-difluoro-7-(1-piperazinyl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid