862574-87-6

• 常用中文名：1-(2,2-二氟苯并二氧代-5-基)环丙烷甲腈
• 常用英文名：1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarbonitrile
• CAS号：862574-87-6
• 分子式：C₁₁H₇F₂NO₂
• 分子量：223.17600
• 发布时间：2018-10-09 17:55:34
• 更新时间：2026-10-07 01:21:18

名称

• 中文名: 1-(2,2-二氟苯并二氧代-5-基)环丙烷甲腈
• 英文名: 1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropane-1-carbonitrile
• 中文别名: K1194(1-(2,2-二氟苯并[D][1,3]二氧杂环戊烯-5-基)环丙基腈); 1-(2,2-二氟-2H-1,3-苯并二噁戊环-5-基)环丙烷-1-甲腈; 鲁玛卡托杂质1; 1-(2,2-二氟苯并[D][1,3]二氧杂环戊烯-5-基)环丙基腈; 1-(2,2-二氟-1,3-苯并二噁茂-5-基)环丙烷甲腈; 1-(2,2-二氟-2H-1,3-苯并二恶唑-5-基)环丙烷-1-腈
• 英文别名: 1-(2,2-Difluoro-2H-1,3-benzodioxol-5-yl)cyclopropane-1-cbo; 1-(2,2-DIFLUOROBENZO[D][1,3]DIOXOL-5-YL)CYCLOPROPANECARBONITRILE; 1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropane-1-carbonitrile; (2,2-difluoro-1,3-benzodioxol-5-yl)-cyclopropanecarbonitrile; 1-(2,2-DIFLUORO-1,3-BENZODIOXOL-5-YL)CYCLOPROPANECARBONITRILE; 1-(2,2-DIFLUORO-1,3-BENZODIOXOL-5-YL)CYCLOPROPANE-1-carbonitrile; 1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropanecbonitrile; Lummakato impurities1; Thiocoraline Impurity14; 1-(2,2-difluorobenzo[1,3]dioxol-5-yl)cyclopropanecarbonitrile; 1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)cyclopropan-carbonitrile; Cyclopropanecbonitrile, 1-(2,2-difluoro-1,3-benzodioxol-5-yl); 1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecbonitrile; EOS-61001

物化性质

• 沸点: 298.7°C at 760 mmHg
• 分子式: C₁₁H₇F₂NO₂
• 分子量: 223.17600
• 精确质量: 223.04400
• PSA: 42.25000
• LogP: 2.56328
• 储存条件: 室温，保存在惰性气体中

合成路线

33070-32-5 ~% 862574-87-6

文献：VERTEX PHARMACEUTICALS INCORPORATED; KESHAVARZ-SHOKRI, Ali; ZHANG, Beili; ALCACIO, Tim, Edward; LEE, Elaine, Chungmin; ZHANG, Yuegang; KRAWIEC, Mariusz Patent: WO2011/119984 A1, 2011 ; WO 2011/119984 A1

656-46-2 ~% 862574-87-6

文献：VERTEX PHARMACEUTICALS INCORPORATED; KESHAVARZ-SHOKRI, Ali; ZHANG, Beili; ALCACIO, Tim, Edward; LEE, Elaine, Chungmin; ZHANG, Yuegang; KRAWIEC, Mariusz Patent: WO2011/119984 A1, 2011 ; WO 2011/119984 A1

72768-97-9 ~% 862574-87-6

文献：VERTEX PHARMACEUTICALS INCORPORATED; KESHAVARZ-SHOKRI, Ali; ZHANG, Beili; ALCACIO, Tim, Edward; LEE, Elaine, Chungmin; ZHANG, Yuegang; KRAWIEC, Mariusz Patent: WO2011/119984 A1, 2011 ; WO 2011/119984 A1

476473-97-9 ~% 862574-87-6

文献：VERTEX PHARMACEUTICALS INCORPORATED; KESHAVARZ-SHOKRI, Ali; ZHANG, Beili; ALCACIO, Tim, Edward; LEE, Elaine, Chungmin; ZHANG, Yuegang; KRAWIEC, Mariusz Patent: WO2011/119984 A1, 2011 ; WO 2011/119984 A1

1335233-51-6 ~% 862574-87-6

文献：VERTEX PHARMACEUTICALS INCORPORATED; KESHAVARZ-SHOKRI, Ali; ZHANG, Beili; ALCACIO, Tim, Edward; LEE, Elaine, Chungmin; ZHANG, Yuegang; KRAWIEC, Mariusz Patent: WO2011/119984 A1, 2011 ; WO 2011/119984 A1

上下游产品

上游产品  4
33070-32-5 656-46-2 72768-97-9 476473-97-9
下游产品  3
862574-88-7 1160221-26-0 1152311-62-0