112811-71-9

• 常用中文名：1-环丙基-6,7-二氟-1,4-二氢-8-甲氧基-4-氧代-3-喹啉羧酸乙酯
• 常用英文名：1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid ethyl ester
• CAS号：112811-71-9
• 分子式：C₁₆H₁₅F₂NO₄
• 分子量：323.291
• 相关类别： 医药中间体 原料药中间体
• 发布时间：2018-04-26 08:00:00
• 更新时间：2024-01-02 11:44:14
• 合成盐酸莫西沙星，盐酸莫西沙星中间体，莫西沙星中间体，加替沙星中间体.

名称

• 中文名: 1-环丙基-6,7-二氟-1,4-二氢-8-甲氧基-4-氧代-3-喹啉羧酸乙酯
• 英文名: 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester
• 中文别名: 1-环丙基-6,7-二氟-1,4-二氢-8-甲氧基-4-氧-3-喹啉甲酸乙酯; 1-环丙基-6,7-二氟-8-甲氧基-4-氧代-1,4-二氢-3-喹啉羧酸乙酯; 加替沙星中间体; 喹啉羧酸乙酯; 1-环丙基-6,7-二氟-8-甲氧基-1,4-二氢-4氧代喹啉基-3-羧酸乙酯; 1-环丙基-6,7-二氟-1.4-二氢-8-甲氧基-4-氧代; 羧酸乙酯; 喹啉羧酸乙酯; 加替环合酯; 加替环内酯; 盐酸莫西沙星中间体
• 英文别名: 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid ethyl ester; MFCD05864419; 3-Quinolinecarboxylic acid, 1-cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-, ethyl ester; Ethyl 1-cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate; 1-cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinoline carboxylic acid ethyl ester; Ethyl 1-cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydro-3-quinolinecarboxylate; Ethyl 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylate; Moxifloxacin Impurity 13

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 459.7±45.0 °C at 760 mmHg
• 熔点: 179-181ºC
• 分子式: C₁₆H₁₅F₂NO₄
• 分子量: 323.291
• 闪点: 231.8±28.7 °C
• 精确质量: 323.096924
• PSA: 57.53000
• LogP: 1.63
• 外观性状: 淡黄色固体
• 蒸汽压: 0.0±1.1 mmHg at 25°C
• 折射率: 1.578
• 储存条件: -20?C Freezer

安全

• 危害码 (欧洲): Xi
• 海关编码: 2933499090

合成路线

112811-65-1 ~% 112811-71-9

文献：European Journal of Medicinal Chemistry, , vol. 41, # 12 p. 1478 - 1493

136897-64-8 ~% 112811-71-9

文献：Journal of Medicinal Chemistry, , vol. 38, # 22 p. 4478 - 4487

122375-85-3 ~% 112811-71-9

文献：Journal of Medicinal Chemistry, , vol. 38, # 22 p. 4478 - 4487

722542-90-7 ~% 112811-71-9

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 11 p. 2773 - 2776

925457-02-9 ~% 112811-71-9

文献：European Journal of Medicinal Chemistry, , vol. 41, # 12 p. 1478 - 1493

112811-70-8 ~% 112811-71-9

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 11 p. 2773 - 2776

112811-66-2 ~% 112811-71-9

文献：European Journal of Medicinal Chemistry, , vol. 41, # 12 p. 1478 - 1493

112811-68-4 ~% 112811-71-9

文献：Journal of Medicinal Chemistry, , vol. 38, # 22 p. 4478 - 4487

上下游产品

上游产品  6
112811-70-8 112811-66-2 112811-65-1 136897-64-8
112811-68-4 122375-85-3
下游产品  2
154093-72-8 112811-72-0

海关

海关编码	2933499090
中文概述	2933499090. 其他含喹琳或异喹啉环系的化合物〔但未进一步稠合的〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%