112811-72-0

• 常用中文名：1-环丙基-6,7-二氟-1,4-二氢-8-甲氧基-4-氧代-3-喹啉羧酸
• 常用英文名：1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid
• CAS号：112811-72-0
• 分子式：C₁₄H₁₁F₂NO₄
• 分子量：295.238
• 发布时间：2018-06-15 17:28:53
• 更新时间：2026-07-03 08:41:50

名称

• 中文名: 1-环丙基-6,7-二氟-1,4-二氢-8-甲氧基-4-氧代-3-喹啉羧酸
• 英文名: 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid
• 中文别名: 莫西沙星二氟含甲氧基的杂质; 加替沙星美国药典杂质C; 莫西沙星母核; 莫西沙星杂质18 CRS; 莫西羧酸; 莫西沙星母核(喹啉羧酸_加替羧酸_喹啉羧酸乙酯_加替环合酯); 加替羧酸(喹啉羧酸); 莫西沙星二氟甲氧基酸杂质; 1-环丙基-6,7-二氟-1,4-二氢-8-甲氧基-4-氧代-3-喹啉甲酸; 加替沙星杂质; 喹啉羧酸1-环丙基-6,7-二氟-1,4-二氢-8-甲氧基-4-氧代-3-喹啉羧酸; 1-环丙基-6,7-二氟-8-甲氧基-4-氧-3-喹啉羧酸; 1-环丙基-6,7-二氟-8-甲氧基-4-氧代-喹啉-3-羧酸; 6-氟加替沙星; 7-氟莫西沙星喹啉羧酸(盐酸莫西沙星杂质); 莫西沙星中间体,莫西沙星母核,加替沙星中间体,1-环丙基-6,7-二氟-1,4-二氢-8-甲氧基-4-氧代-3-喹啉羧酸; 盐酸莫西沙星杂质1; 加替羧酸,莫西羧酸,1-环丙基-6,7-二氟-1,4-二氢-8-甲氧基-4-氧代-3-喹啉羧酸; 莫西沙西母环; 莫西沙星杂质SM-6; 莫西沙星中间体,加替沙星中间体,1-环丙基-6,7-二氟-1,4-二氢-8-甲氧基-4-氧代-3-喹啉羧酸; 莫西沙星杂质26; 莫西沙星杂质J; 莫西羧酸(加替羧酸); 加替沙星酸; 莫西沙星相关物质; 1-环丙基-6,7-二氟-4-氧代-8-甲氧基-喹啉-3-羧酸; 莫西沙星杂质; 1-环丙基-6,7-二氟-8-甲氧基-4-氧代-3-喹啉羧酸; 盐酸莫西沙星中间体1-环丙基-6,7-二氟-1,4-二氢-8-甲氧基-4-氧代-3-喹啉羧酸; 环丙沙星杂质8; 加替羧酸、莫西羧酸; 1-环丙基-6,7-二氟-1,4-二氢-8-甲氧基-4-氧-3-喹啉羧酸; 喹啉羧酸; 莫西沙星二氟甲氧基杂质; 莫西杂质I; 加替沙星中间体; 莫西沙星相关化合物G; 莫西沙星相关化合物26; 1-环丙基-6,7-二氟-8-甲氧基-4-氧代喹啉-3-羧酸; 1-CYCLOPROPYL-6锛-DIFLUORO-8-METHOXY-4-OXO-1锛-DIHYDROQUINOLINE-3-CBOXYLIC ACID; 环丙沙星二氟8-甲氧基杂质; 莫西沙星 中间体 MO-2.1; 1-环丙基-6,7-二氟-8-甲氧基-4-氧代-1,4-二氢3-喹啉羧酸; 莫西沙星杂质J(环丙沙星杂质8); 1-环丙基-4-氧代-6,7-二氟-8-甲氧基-3-喹啉甲酸; 1-环丙基-6,7-二氟-1,4-二氢-8-甲氧基-4-氧代-3-喹啉羧酸(莫西沙星杂质); 盐酸莫西沙星杂质G (1-环丙基-6,7-二氟-8-甲氧基-4-氧代-1,4-二氢喹啉-3-羧酸)
• 英文别名: Moxifloxacin Impurity J (1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecboxylic acid); 1-Cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydroquinolin-3-cboxylic acid; 1-cyclopropyl-6,7-difluoro-1,4-dihydhro-8-methoxy-4-oxo-3-quinolinecboxylic acid; 6,7-DIFLUORO-8-METHOXY QUINOLINIC ACID; Gatifloxacin impurity C; 1-CYCLOPROPYL-6,7-DIFLUORO-8-METHOXY-4-OXO-1,4-DIHYDROQUINOLINE-3-CBOXYLIC ACID; Moxifloxacin Difluoro Methoxy IMpurity; 1-CYCLOPROPYL-6,7-DIFLUORO-8-METHOXY-4-OXO-3-QUINOLINECBOXYLIC ACID; Quinoline cboxylic acid; Gatifloxacin Impurity: 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecboxylic acid; 1-Cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-3-quinolinecarboxylic acid; 1-Cyclopropyl-6,7-difluoro-1; 1-Cyclopropyl6,7Dihydro-8-Methoxy-4-Oxo-3-QuinoiineCboxylicAcid,MoxifloxacinHcl; Moxifloxacin Difluoro Methoxy Acid Impurity; 1-cyclopropy,7-difluoro-1,4-dihydhro-8-methoxy-x-quinoline cboxylic acid; Difluoromethoxy gatifloxacin; Moxifloxacin Impurity 18 CRS; Ciprofloxacin Impurity 8; Gatifloxacin Related Compound C (Moxifloxacin Difluoro Methoxy Acid Impurity/ Ciprofloxacin Difluoro 8-Methoxy Impurity); Moxifloxacin Related Compound 26; MOXI Q-ACID; 1-cyclopropyl-6,7-difluoro-1,4-dihydro-8- methoxy-4-oxo-3-quinolinecboxylic acidQ: What is 1-cyclopropyl-6,7-difluoro-1,4-dihydro-8- methoxy-4-oxo-3-quinolinecboxylic acid Q: What is the CAS Number of 1-cyclopropyl-6,7-difluoro-1,4-dihydro-8- methoxy-4-oxo-3-quinolinecboxylic acid Q: What is the storage condition of 1-cyclopropyl-6,7-difluoro-1,4-dihydro-8- methoxy-4-oxo-3-quinolinecboxylic acid Q: What e the applications of 1-cyclopropyl-6,7-difluoro-1,4-dihydro-8- methoxy-4-oxo-3-quinolinecboxylic acid; 1-Cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid; Gatifloxacin Impurity1379; 1-cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-quinoline-3-cboxylic acid; 1-Cyclopropyl-6; Gati Acid; GatifloxacinCboxylicAcid(QuinolinecboxylicAcid); Ciprofloxacin Difluoro 8-Methoxy Impurity (Gatifloxacin Related Compound C/ Moxifloxacin Difluoro Methoxy Acid Impurity); 1-Cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-3-quinolinecboxylic; Gatecboxylic acid; Mosisasin Impurity 1; 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecboxylic acid ISO 9001：2015 REACH; 1-cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecboxylic acid; Moxifloxacin main chain; Moxifloxacin Impurity J（Ciprofloxacin Impurity 8）; 1-Cyclo Propyl-6,7-Difluoro-1,4-Dihydro-8-Methoxy-4-Oxo-3-Quinoiineboxylic acid; 7-Fluoromoxifloxacinquinolinecboxylic Acid(Moxifloxacin Hydrochloride Impurity); 1-Cyclopropyl-6,7-difluoro-8-methoxy-4-o xo-1,4-dihydroquine; 1-Cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-cboxylic acid (Moxifloxacin Impurity); Azilstan medoxomil impurity283; 1-Cyclopropyl-6,7-Difluoro-8-Methoxy-4-Oxo-1,4-dihydroquinoline-3-carboxylic acid; Moxifloxacin Impurity 26; MFCD05864420; Moxifloxacin Related CoMpound (1-Cyclopropyl-6,7-Difluoro-8-Methoxy-4-Oxo-1,4-Dihydroquinoline-3-Cboxylic Acid); Moxifloxacin Impurity J; EINECS 214-439-2; Moxifloxacin-9; 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-quinolin-3-cboxylic acid; 3-QUINOLINECBOXYLIC ACID, 1-CYCLOPROPYL-6,7-DIFLUORO-1,4-DIHYDRO-8-METHOXY-4-OXO; 1-cyclopropyl-6,7-difluoro-8-methoxy-4-oxoquinoline-3-cboxylic acid; 1-cyclopropyl-6,7-difluoro-4-keto-8-methoxy-quinoline-3-cboxylic acid; Moxifloxacin Methoxy Quinolin Impurity; 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecboxylic Aci; Ciprofloxacin Difluoro 8-Methoxy Impurity; Antibacterial agent; Gatifloxacin RC C

物化性质

• 密度: 1.6±0.1 g/cm3
• 沸点: 474.4±45.0 °C at 760 mmHg
• 熔点: 192-194ºC
• 分子式: C₁₄H₁₁F₂NO₄
• 分子量: 295.238
• 闪点: 240.7±28.7 °C
• 精确质量: 295.065613
• PSA: 68.53000
• LogP: 1.33
• 外观性状: 灰白色至淡黄色粉末
• 蒸汽压: 0.0±1.2 mmHg at 25°C
• 折射率: 1.630
• 储存条件: Refrigerator

安全

• 危害码 (欧洲): Xn
• 风险声明 (欧洲): 22
• 海关编码: 2918990090

合成路线

112811-71-9 ~95% 112811-72-0

文献：Li, Fei; Zhang, Jie; Jiang, Yu; Jin, Lei; Zhang, Chuan Asian Journal of Chemistry, 2013 , vol. 25, # 11 p. 6079 - 6082

154093-72-8 77-78-1 ~% 141290-02-0 112811-72-0

文献：WO2006/4561 A1, ; Page/Page column title page; 4; 12-13 ;

112811-70-8 ~% 112811-72-0

文献：Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, , vol. 121, p. 254 - 258

141290-02-0 ~% 112811-72-0

文献：WO2006/4561 A1, ; Page/Page column title page; 4; 12-13 ;

上下游产品

上游产品  4
112811-71-9 154093-72-8 77-78-1 112811-70-8
下游产品  4
154093-72-8 160738-57-8 151096-09-2 186826-86-8

海关

海关编码	2918990090
中文概述	2918990090. 其他含其他附加含氧基羧酸（包括酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%