CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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PA5270000
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CHEMICAL NAME :
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Methane, bromochlorodifluoro-
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CAS REGISTRY NUMBER :
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353-59-3
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BEILSTEIN REFERENCE NO. :
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1732514
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LAST UPDATED :
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199801
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DATA ITEMS CITED :
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11
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MOLECULAR FORMULA :
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C-Br-Cl-F2
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MOLECULAR WEIGHT :
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165.37
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WISWESSER LINE NOTATION :
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GXFFE
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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TCLo - Lowest published toxic concentration
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Human - man
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DOSE/DURATION :
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4 pph/1M
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TOXIC EFFECTS :
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Peripheral Nerve and Sensation - paresthesis Behavioral - hallucinations, distorted perceptions Cardiac - EKG changes not diagnostic of specified effects
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TYPE OF TEST :
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LC50 - Lethal concentration, 50 percent kill
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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20 pph/15M
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TOXIC EFFECTS :
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Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory depression
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TYPE OF TEST :
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LCLo - Lowest published lethal concentration
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Mammal - dog
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DOSE/DURATION :
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5 pph/30M
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TOXIC EFFECTS :
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Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Cardiac - other changes
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TYPE OF TEST :
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LCLo - Lowest published lethal concentration
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - guinea pig
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DOSE/DURATION :
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30 pph/2H
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TOXIC EFFECTS :
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Behavioral - convulsions or effect on seizure threshold
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TYPE OF TEST :
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TCLo - Lowest published toxic concentration
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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210 ug/m3/4H/12W-I
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TOXIC EFFECTS :
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Blood - pigmented or nucleated red blood cells Blood - changes in erythrocyte (RBC) count Blood - changes in platelet count
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TYPE OF TEST :
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TCLo - Lowest published toxic concentration
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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1 pph/6H/3W-I
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TOXIC EFFECTS :
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Behavioral - somnolence (general depressed activity)
MUTATION DATA
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TYPE OF TEST :
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Mutation in microorganisms
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TEST SYSTEM :
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Bacteria - Salmonella typhimurium
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DOSE/DURATION :
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10 pph
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REFERENCE :
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MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 142,187,1985 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 1000 mg/m3 JAN 1993
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