CHEMICAL IDENTIFICATION
-
RTECS NUMBER :
-
JI1800000
-
CHEMICAL NAME :
-
1,3-Dioxolane-4-methanol, 2-(1-iodoethyl)-
-
CAS REGISTRY NUMBER :
-
5634-39-9
-
LAST UPDATED :
-
199806
-
DATA ITEMS CITED :
-
14
-
MOLECULAR FORMULA :
-
C6-H11-I-O3
-
MOLECULAR WEIGHT :
-
258.07
-
WISWESSER LINE NOTATION :
-
T5O COTJ BYI1 D1Q &T5O COTJ B2I D1Q
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Oral
-
SPECIES OBSERVED :
-
Rodent - rat
-
DOSE/DURATION :
-
6 gm/kg/16D-I
-
TOXIC EFFECTS :
-
Related to Chronic Data - death
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Oral
-
SPECIES OBSERVED :
-
Rodent - rat
-
DOSE/DURATION :
-
32500 mg/kg/13W-I
-
TOXIC EFFECTS :
-
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Related to Chronic Data - death
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Oral
-
SPECIES OBSERVED :
-
Rodent - mouse
-
DOSE/DURATION :
-
32500 mg/kg/13W-I
-
TOXIC EFFECTS :
-
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Related to Chronic Data - death
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Oral
-
SPECIES OBSERVED :
-
Rodent - rat
-
DOSE/DURATION :
-
64375 mg/kg/2Y-C
-
TOXIC EFFECTS :
-
Tumorigenic - Carcinogenic by RTECS criteria Endocrine - thyroid tumors Blood - tumors
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Oral
-
SPECIES OBSERVED :
-
Rodent - mouse
-
DOSE/DURATION :
-
64375 mg/kg/2Y-C
-
TOXIC EFFECTS :
-
Tumorigenic - neoplastic by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors Endocrine - tumors
-
TYPE OF TEST :
-
Sister chromatid exchange
MUTATION DATA
-
TYPE OF TEST :
-
Sister chromatid exchange
-
TEST SYSTEM :
-
Rodent - hamster Ovary
-
DOSE/DURATION :
-
167 mg/L
-
REFERENCE :
-
NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-340,1990 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81848 No. of Facilities: 864 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 1099 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81848 No. of Facilities: 85 (estimated) No. of Industries: 2 No. of Occupations: 6 No. of Employees: 854 (estimated) No. of Female Employees: 265 (estimated)
|
