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上海化源世纪贸易有限公司
上海市上海市普陀区
产品名：地那林
纯度：98.0%
规格：
联系人：徐经理
联系电话：13311869306

上海阿拉丁生化科技股份有限公司
上海市上海市浦东新区
产品名：地那林
纯度：98.0%
规格：50mg/1g/1g/1g
联系人：阿拉丁
联系电话：400-620-6333

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58338-59-3生产厂家

58338-59-3价格

58338-59-3

58338-59-3结构式

常用中文名：地那林
常用英文名：Benzamide,4-amino-N-(2-aminophenyl)-
CAS号：58338-59-3
分子式：C₁₃H₁₃N₃O
分子量：227.26200
发布时间：2018-03-23 08:00:00
更新时间：2024-09-26 17:43:41

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中文名	地那林
英文名	4-amino-N-(2-aminophenyl)benzamide
英文别名	Goe-1734 4-Amino-N-(2'-aminophenyl)-benzamide Dinaline [INN] Dinalina [Spanish] 2',4-Diaminobenzanilide Dinaline [French] 2',4-Diaminobenzanilid Dinaline Dianiline Dinalinum [Latin]

密度	1.314g/cm3
沸点	367.2ºC at 760mmHg
分子式	C₁₃H₁₃N₃O
分子量	227.26200
闪点	175.9ºC
精确质量	227.10600
PSA	81.14000
LogP	3.33870
折射率	1.734

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CU8994000

CHEMICAL NAME :: Benzamide, 4-amino-N-(2-aminophenyl)-

CAS REGISTRY NUMBER :: 58338-59-3

LAST UPDATED :: 199612

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C13-H13-N3-O

MOLECULAR WEIGHT :: 227.29

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 95 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 625 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 630 mg/kg/6W-I

TOXIC EFFECTS :: Blood - changes in bone marrow (not otherwise specified) Blood - changes in erythrocyte (RBC) count Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 462 mg/kg/14W-I

TOXIC EFFECTS :: Blood - changes in bone marrow (not otherwise specified)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 6678 mg/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Endocrine - adrenal cortex tumors Reproductive - Maternal Effects - uterus, cervix, vagina

MUTATION DATA

TEST SYSTEM :: Rodent - rat

DOSE/DURATION :: 10 mg/kg

REFERENCE :: CTRRDO Cancer Treatment Reports. (Washington, DC) V.60-71, 1976-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 69,1415,1985

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