76824-16-3

• 常用中文名：3-[[[2-[(氨基亚胺甲基)氨基]-4-噻唑基]甲基]硫基]丙酰胺
• 常用英文名：3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]propanamide
• CAS号：76824-16-3
• 分子式：C₈H₁₃N₅OS₂
• 分子量：259.35200
• 相关类别： 分析化学 标准品 药典标准品和杂志标准品
• 发布时间：2018-12-18 00:14:33
• 更新时间：2026-08-03 17:39:42

名称

• 中文名: 3-[[[2-[(氨基亚胺甲基)氨基]-4-噻唑基]甲基]硫基]丙酰胺
• 英文名: 3-[({2-[(Diaminomethylene)amino]-1,3-thiazol-4-yl}methyl)sulfanyl ]propanamide
• 中文别名: 法莫替丁杂质D; 法莫替丁D; 法莫替丁杂质D D; 3-(((2-胍基噻唑-4-基)甲基)硫代)丙酰胺; 法莫替丁杂质Ⅱ3-[[[2-[(二氨基亚甲基)氨基]-4-噻唑基]甲基]硫基]丙酰胺; 法莫替丁杂质4(法莫替丁杂质D); 法莫替丁杂质Ⅱ3-[[[2-[（二氨基亚甲基）氨基]-4-噻唑基]甲基]硫基]丙酰胺; 盐酸法莫替丁酰胺杂质; 3-(((2-胍基噻唑-4-基)甲基)硫代)丙酰胺 (法莫替丁杂质); 法莫替丁 杂质 D(法莫替丁 相关化合物 D); 法莫替丁杂质D(盐酸法莫替丁酰胺杂质); 法莫替丁相关化合物D; 法莫替丁相关物质D 标准品; 法莫替丁相关物质D; 法莫替丁杂质D 标准品
• 英文别名: Famotidine Related Compound D (25 mg) (3-[[2-(diaminomethyleneamino)thiazol-4-yl]methylthio]propanamide); 3-(((2-Guanidinothiazol-4-yl)methyl)thio)propanamide (Famotidine Impurity); Propanamide, 3-[[[2-[(aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]; 3-[[[2-[(AMinoiMinoMethyl)amino]-4-thiazolyl]Methyl]thio]propanaMide; 3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]propanamide/Famotidine Amide Impurity Hydrochloride; 3-(((2-Guanidinothiazol-4-yl)methyl)thio)propanamide; Famotidine Impurity D (Famotidine Related Compound D); Famotidine Impurity Ⅱ:3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]propanamide; Famotidine Impurity D,Famotidine Related Compound C; FaMotidine Related CoMpound D; Famotidine Compound D; Famotidine propanamide; 3-[[[2-[(Diaminomethylene)amino]thiazol-4-yl]methyl]sulfanyl]propanamide; Imp. D : 3-[[[2-[(Diaminomethylene)-amino]thiazol-4-yl]methyl]sulfanyl]-propanamide; Famotidine Impurity D RC D); 3-[[[2-[(Diaminomethylidene)amino]thiazol-4-yl]methyl]sulfanyl]propanamide; 3-(((2-((diaminomethylene)amino)thiazol-4-yl)methyl)thio)propanamide; Famotidine impurity D CRS; Famotidine Impurity D; 3-[[[2-[(Diaminomethylene)amino]-4-thiazolyl]methyl]thio]propanamide; Famotidine Imp. D : 3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]propanamide; Famotidine Related Compound D (3-[[2-(diaminomethyleneamino)thiazol-4-yl]methylthio]propanamide); Famotidine Impurity 4(Famotidine Impurity D); 3-{{{2-[(Diaminomethylene)amino]thiazol-4-yl}methyl}sulphanyl}propanamide; 3-(((2-((DIAMINOMETHYLENE)AMINO)THIAZOL-4-YL)METHYL)THIO)-N-SULFAMOYLPROPANIMIDAMIDE; Famotidine Impurity D/ Famotidine Related Compound D; (dismonomethylene）amino］-4-thiazolyl］methyl］thio］; FaMotidine AMide IMpurity; Famotidine Impurity 4; amotidine Impurity D

物化性质

• 密度: 1.63±0.1 g/cm3
• 分子式: C₈H₁₃N₅OS₂
• 分子量: 259.35200
• 精确质量: 259.05600
• PSA: 172.41000
• LogP: 2.57980
• 水溶解性: Slightly soluble (2.5 g/L) (25 ºC)

安全

• 危险品运输编码: NONH for all modes of transport

合成路线

76823-94-4 ~65% 76824-16-3

文献：Yanagisawa; Hirata; Ishii Journal of medicinal chemistry, 1984 , vol. 27, # 7 p. 849 - 857

76823-89-7 ~% 76824-16-3

文献：Yanagisawa; Hirata; Ishii Journal of medicinal chemistry, 1984 , vol. 27, # 7 p. 849 - 857

76823-93-3 ~% 76824-16-3

文献：Yanagisawa; Hirata; Ishii Journal of medicinal chemistry, 1984 , vol. 27, # 7 p. 849 - 857

76823-91-1 ~% 76824-16-3

文献：Yanagisawa; Hirata; Ishii Journal of medicinal chemistry, 1984 , vol. 27, # 7 p. 849 - 857

76823-90-0 ~% 76824-16-3

文献：Yanagisawa; Hirata; Ishii Journal of medicinal chemistry, 1984 , vol. 27, # 7 p. 849 - 857

76823-92-2 ~% 76824-16-3

文献：Yanagisawa; Hirata; Ishii Journal of medicinal chemistry, 1984 , vol. 27, # 7 p. 849 - 857