64118-86-1

• 常用中文名：阿齐美克
• 常用英文名：1-[2-(2-cyanoaziridin-1-yl)propan-2-yl]aziridine-2-carboxamide
• CAS号：64118-86-1
• 分子式：C₉H₁₄N₄O
• 分子量：194.23400
• 发布时间：2018-06-11 11:00:22
• 更新时间：2024-01-02 16:55:21

名称

• 中文名: 阿齐美克
• 英文名: 1-[2-(2-cyanoaziridin-1-yl)propan-2-yl]aziridine-2-carboxamide
• 英文别名: 2-(2-Cyan-aziridin-1-yl)-2-(2-carbamoyl-aziridin-1-yl)-propan; Azimexon; azimexone; Azimexonum [INN-Latin]; Azimexona [Spanish]; Azimexone [Polish]; Azimexona [INN-Spanish]; 2-(2-Cyan-aziridinyl-1)-2-(2-carbamoyl-aziridinyl-1)-propan; 1-[1-(2-cyano-aziridin-1-yl)-1-methyl-ethyl]-aziridine-2-carboxylic acid amide; EINECS 264-679-7; 2-(2-carbamoyl-aziridino)-2-(2-cyano-aziridino)-cyclohexane

物化性质

• 密度: 1.29g/cm3
• 沸点: 403.4ºC at 760 mmHg
• 分子式: C₉H₁₄N₄O
• 分子量: 194.23400
• 闪点: 197.8ºC
• 精确质量: 194.11700
• PSA: 72.90000
• 折射率: 1.598

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : CM6754000 CHEMICAL NAME : 2-Aziridinecarboxamide, 1-(1-(2-cyano-1-aziridinyl)-1-methylethyl)- CAS REGISTRY NUMBER : 64118-86-1 BEILSTEIN REFERENCE NO. : 0476876 LAST UPDATED : 199709 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C9-H14-N4-O MOLECULAR WEIGHT : 194.27 WISWESSER LINE NOTATION : T3NTJ BVZ AX1&1&- AT3NTJ BCN HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 3100 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4370323 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 2550 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4370323 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1400 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 5,174,1980 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 560 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.10- 1962- Volume(issue)/page/year: 34,333,1986