| 中文名 | 2-(4-异丁基苯基)丙酰肼 |
|---|---|
| 英文名 | 2-[4-(2-methylpropyl)phenyl]propanehydrazide |
| 中文别名 | 2-(4-异丁基苯基)丙肼 |
| 英文别名 | ibuprofen hydrazide |
| 密度 | 1.023g/cm3 |
|---|---|
| 沸点 | 395.8ºC at 760 mmHg |
| 熔点 | 76ºC |
| 分子式 | C13H20N2O |
| 分子量 | 220.31100 |
| 闪点 | 193.2ºC |
| 精确质量 | 220.15800 |
| PSA | 55.12000 |
| LogP | 3.06970 |
| 蒸汽压 | 1.79E-06mmHg at 25°C |
| 折射率 | 1.528 |
| 储存条件 | 室温 |
Synonym:2-[4-(Isobutyl)phenyl]propionyl hydrazid Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin. Potential Health Effects Eye: Causes eye irritation. Skin: Causes skin irritation. May be harmful if absorbed through the skin. Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed. Inhalation: Causes respiratory tract irritation. May be harmful if inhaled. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 127222-69-9: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: white Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 70 - 72 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C13H20N2O Molecular Weight: 220 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Not available. Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 127222-69-9 unlisted. LD50/LC50: Not available. Carcinogenicity: 2-(4-Isobutylphenyl)propanohydrazide - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA No information available. IMO No information available. RID/ADR No information available. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XI Risk Phrases: R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 Wear suitable gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 127222-69-9: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 127222-69-9 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 127222-69-9 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A |
| 危害码 (欧洲) | Xi |
|---|---|
| 风险声明 (欧洲) | R36/37/38 |
| 安全声明 (欧洲) | S26-S37/39 |
| 海关编码 | 2928000090 |
|
~61%
127222-69-9 |
| 文献：Sharma, Vibha; Khan Pharmazie, 2003 , vol. 58, # 2 p. 99 - 103 |
|
~86%
127222-69-9 |
| 文献：Perkovic; Butula; Kralj; Martin-Kleiner; Balzarini; Hadjipavlou-Litina; Katsori; Zorc European Journal of Medicinal Chemistry, 2012 , vol. 51, p. 227 - 238 |
|
~%
127222-69-9 |
| 文献：Bioorganic Chemistry, , vol. 52, p. 8 - 15 |
|
~84%
127222-69-9 |
| 文献：Kumsi, Manjunatha; Poojary, Boja; Lobo, Prajwal Lourdes; Kumari, Nalilu Suchetha; Chullikana, Anoop Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 2010 , vol. 65, # 12 p. 1509 - 1515 |
|
~87%
127222-69-9 |
| 文献：Kumsi, Manjunatha; Poojary, Boja; Lobo, Prajwal L.; Fernandes, Jennifer; Chikkanna, Chandrashekhar Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 2010 , vol. 65, # 11 p. 1353 - 1358 |
| 上游产品 4 | |
|---|---|
| 下游产品 0 | |
| 海关编码 | 2928000090 |
|---|---|
| 中文概述 | 2928000090 其他肼（联氨）及胲（羟胺）的有机衍生物。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:20.0% |
| 申报要素 | 品名, 成分含量, 用途 |
| Summary | 2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0% |
