127222-69-9

127222-69-9 structure
127222-69-9 structure
  • Name: 2-(4-Isobutylphenyl)propanohydrazide
  • Chemical Name: 2-[4-(2-methylpropyl)phenyl]propanehydrazide
  • CAS Number: 127222-69-9
  • Molecular Formula: C13H20N2O
  • Molecular Weight: 220.31100
  • Create Date: 2018-03-07 08:00:00
  • Modify Date: 2024-01-02 17:51:04

Name 2-[4-(2-methylpropyl)phenyl]propanehydrazide
Synonyms ibuprofen hydrazide
Density 1.023g/cm3
Boiling Point 395.8ºC at 760 mmHg
Melting Point 76ºC
Molecular Formula C13H20N2O
Molecular Weight 220.31100
Flash Point 193.2ºC
Exact Mass 220.15800
PSA 55.12000
LogP 3.06970
Vapour Pressure 1.79E-06mmHg at 25°C
Index of Refraction 1.528
Name: 2-(4-Isobutylphenyl)propanohydrazide 95+% Material Safety Data Sheet
Synonym: 2-[4-(Isobutyl)phenyl]propionyl hydrazid
CAS: 127222-69-9
Section 1 - Chemical Product MSDS Name:2-(4-Isobutylphenyl)propanohydrazide 95+% Material Safety Data Sheet
Synonym:2-[4-(Isobutyl)phenyl]propionyl hydrazid

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
127222-69-9 2-(4-Isobutylphenyl)propanohydrazide 95+% unlisted
Hazard Symbols: XI
Risk Phrases: 36/37/38

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
Causes respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 127222-69-9: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: white
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 70 - 72 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C13H20N2O
Molecular Weight: 220

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Not available.

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 127222-69-9 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
2-(4-Isobutylphenyl)propanohydrazide - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
No information available.
IMO
No information available.
RID/ADR
No information available.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 37/39 Wear suitable gloves and eye/face
protection.
WGK (Water Danger/Protection)
CAS# 127222-69-9: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 127222-69-9 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 127222-69-9 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases S26-S37/39
HS Code 2928000090

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127222-69-9

Literature: Sharma, Vibha; Khan Pharmazie, 2003 , vol. 58, # 2 p. 99 - 103

~86%

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127222-69-9

Literature: Perkovic; Butula; Kralj; Martin-Kleiner; Balzarini; Hadjipavlou-Litina; Katsori; Zorc European Journal of Medicinal Chemistry, 2012 , vol. 51, p. 227 - 238

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127222-69-9 structure

127222-69-9

Literature: Bioorganic Chemistry, , vol. 52, p. 8 - 15

~84%

127222-69-9 structure

127222-69-9

Literature: Kumsi, Manjunatha; Poojary, Boja; Lobo, Prajwal Lourdes; Kumari, Nalilu Suchetha; Chullikana, Anoop Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 2010 , vol. 65, # 12 p. 1509 - 1515

~87%

127222-69-9 structure

127222-69-9

Literature: Kumsi, Manjunatha; Poojary, Boja; Lobo, Prajwal L.; Fernandes, Jennifer; Chikkanna, Chandrashekhar Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 2010 , vol. 65, # 11 p. 1353 - 1358
HS Code 2928000090
Summary 2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%