60706-43-6

• 常用中文名：10-[2-(4-methylpiperazin-1-yl)ethyl]phenothiazine
• 常用英文名：10-[2-(4-methylpiperazin-1-yl)ethyl]phenothiazine
• CAS号：60706-43-6
• 分子式：C₁₉H₂₃N₃S
• 分子量：325.47100
• 发布时间：2016-12-07 19:28:06
• 更新时间：2024-01-24 11:11:09

名称

• 英文名: 10-[2-(4-methylpiperazin-1-yl)ethyl]phenothiazine
• 英文别名: 10-[2-(4-methyl-piperazin-1-yl)-ethyl]-10H-phenothiazine; N-Methyl-piperazinyl-N'-aethyl-phenothiazin [German]; 10-(2-(4-Methyl-1-piperazinyl)ethyl)phenothiazine; 10-[2-(4-Methyl-piperazino)-aethyl]-phenothiazin; P 527; Phenothiazine,10-(2-(4-methyl-1-piperazinyl)ethyl); 10-[2-(4-methyl-piperazino)-ethyl]-phenothiazine

物化性质

• 密度: 1.167g/cm3
• 沸点: 479.5ºC at 760 mmHg
• 分子式: C₁₉H₂₃N₃S
• 分子量: 325.47100
• 闪点: 243.8ºC
• 精确质量: 325.16100
• PSA: 35.02000
• LogP: 3.47750
• 折射率: 1.624

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : SP1130000 CHEMICAL NAME : Phenothiazine, 10-(2-(4-methyl-1-piperazinyl)ethyl)- CAS REGISTRY NUMBER : 60706-43-6 BEILSTEIN REFERENCE NO. : 0038803 LAST UPDATED : 199612 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C19-H23-N3-S MOLECULAR WEIGHT : 325.51 WISWESSER LINE NOTATION : T C666 BN ISJ B2- AT6N DNTJ D1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 135 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 7,106,1957 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 220 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 7,106,1957 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 640 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 7,106,1957 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 135 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 7,106,1957 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 36 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 7,106,1957