60706-43-6

60706-43-6 structure

60706-43-6 structure

Name: 10-[2-(4-methylpiperazin-1-yl)ethyl]phenothiazine
Chemical Name: 10-[2-(4-methylpiperazin-1-yl)ethyl]phenothiazine
CAS Number: 60706-43-6
Molecular Formula: C₁₉H₂₃N₃S
Molecular Weight: 325.47100
Create Date: 2016-12-07 19:28:06
Modify Date: 2024-01-24 11:11:09

Name	10-[2-(4-methylpiperazin-1-yl)ethyl]phenothiazine
Synonyms	10-[2-(4-methyl-piperazin-1-yl)-ethyl]-10H-phenothiazine N-Methyl-piperazinyl-N'-aethyl-phenothiazin [German] 10-(2-(4-Methyl-1-piperazinyl)ethyl)phenothiazine 10-[2-(4-Methyl-piperazino)-aethyl]-phenothiazin P 527 Phenothiazine,10-(2-(4-methyl-1-piperazinyl)ethyl) 10-[2-(4-methyl-piperazino)-ethyl]-phenothiazine

Density	1.167g/cm3
Boiling Point	479.5ºC at 760 mmHg
Molecular Formula	C₁₉H₂₃N₃S
Molecular Weight	325.47100
Flash Point	243.8ºC
Exact Mass	325.16100
PSA	35.02000
LogP	3.47750
Index of Refraction	1.624

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SP1130000

CHEMICAL NAME :: Phenothiazine, 10-(2-(4-methyl-1-piperazinyl)ethyl)-

CAS REGISTRY NUMBER :: 60706-43-6

BEILSTEIN REFERENCE NO. :: 0038803

LAST UPDATED :: 199612

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C19-H23-N3-S

MOLECULAR WEIGHT :: 325.51

WISWESSER LINE NOTATION :: T C666 BN ISJ B2- AT6N DNTJ D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 135 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 7,106,1957

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 220 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 7,106,1957

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 640 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 7,106,1957

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 135 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 7,106,1957

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 36 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 7,106,1957