495-70-5

• 常用中文名：美普卡因
• 常用英文名：Meprylcaine
• CAS号：495-70-5
• 分子式：C₁₄H₂₁NO₂
• 分子量：235.32200
• 发布时间：2018-07-17 12:55:51
• 更新时间：2024-01-10 19:55:51

名称

• 中文名: 美普卡因
• 英文名: [2-methyl-2-(propylamino)propyl] benzoate
• 英文别名: Benzoesaeure-(2-methyl-2-propylaminopropylester); Epirocaine; Epirocain; Meprylcainum [INN-Latin]; Meprylcaine [INN]; Oracaine; 1-Benzoyloxy-2-methyl-2-propylamino-propan; Meprilcaino [INN-Spanish]; 2-Methyl-2-(propylamino)-1-propanol benzoate; MEPRYLCAINE; 1-benzoyloxy-2-methyl-2-propylamino-propane

物化性质

• 密度: 1g/cm3
• 沸点: 329.5ºC at 760mmHg
• 分子式: C₁₄H₂₁NO₂
• 分子量: 235.32200
• 闪点: 153.1ºC
• 精确质量: 235.15700
• PSA: 38.33000
• LogP: 3.01250
• 蒸汽压: 0.000177mmHg at 25°C
• 折射率: 1.501

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UB8654200 CHEMICAL NAME : 1-Propanol, 2-methyl-2-(propylamino)-, benzoate (ester) CAS REGISTRY NUMBER : 495-70-5 BEILSTEIN REFERENCE NO. : 2581683 LAST UPDATED : 199612 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C14-H21-N-O2 MOLECULAR WEIGHT : 235.36 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 195 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - tremor REFERENCE : TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 9,38,1962 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 470 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - tremor REFERENCE : TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 9,38,1962 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 20 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - tremor REFERENCE : TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 9,38,1962

合成路线

55968-10-0 98-88-4 ~% 495-70-5

文献：Mizzy Inc. Patent: US2767207 , 1953 ;