99741-73-8
99741-73-8结构式
- 常用中文名：Alpha 4-甲代亚苯基二异氰酸
- 常用英文名：1-Isocyanato-4-(isocyanatomethyl)benzene
- CAS号：99741-73-8
- 分子式：C9H6N2O2
- 分子量：174.15600
- 发布时间：2018-11-26 10:34:33
- 更新时间：2024-02-04 18:03:13
| 中文名 | Alpha 4-甲代亚苯基二异氰酸 |
|---|---|
| 英文名 | 1-Isocyanato-4-(isocyanatomethyl)benzene |
| 英文别名 |
Benzene,1-isocyanato-4-(isocyanatomethyl)
4-isocyanato-benzyl isocyanate p-tolylene diisocyanate 4-Isocyanato-benzylisocyanat Tolylendiisocyanat |
| 密度 | 1.218 g/mL at 25ºC(lit.) |
|---|---|
| 沸点 | 152ºC19 mm Hg(lit.) |
| 分子式 | C9H6N2O2 |
| 分子量 | 174.15600 |
| 闪点 | >230 °F |
| 精确质量 | 174.04300 |
| PSA | 58.86000 |
| LogP | 1.48970 |
| 折射率 | n20/D 1.557(lit.) |
| 储存条件 | 保持贮藏器密封、储存在阴凉、干燥的地方，确保工作间有良好的通风或排气装置 |
| 稳定性 | 如果遵照规格使用和储存则不会分解，未有已知危险反应，避免强氧化物 |
| 分子结构 | 五、分子性质数据： 1、 摩尔折射率：49.28 2、 摩尔体积（m3/mol）：152.8 3、 等张比容（90.2K）：397.8 4、 表面张力（dyne/cm）：45.8 5、 介电常数：无可用的 6、 偶极距（10 -24cm 3）：无可用的 7、 极化率：19.53 |
| 计算化学 | 1.疏水参数计算参考值（XlogP）:3.5 2.氢键供体数量:0 3.氢键受体数量:4 4.可旋转化学键数量:3 5.互变异构体数量:无 6.拓扑分子极性表面积58.9 7.重原子数量:13 8.表面电荷:0 9.复杂度:244 10.同位素原子数量:0 11.确定原子立构中心数量:0 12.不确定原子立构中心数量:0 13.确定化学键立构中心数量:0 14.不确定化学键立构中心数量:0 15.共价键单元数量:1 |
| 更多 | 1. 性状：未确定 2. 密度（g/mL,25ºC）：1.218 3. 相对蒸汽密度（g/mL,空气=1）：未确定 4. 熔点（ºC）：未确定 5. 沸点（ºC）：未确定 6. 沸点（ºC，19mmHg）：152 7. 折射率：n 20/D 1.557(lit.) 8. 闪点（°F）：>230 9. 比旋光度（ºF）：未确定 10. 自燃点或引燃温度（ºC）：未确定 11. 蒸气压（kPa,20ºC）：未确定 12. 饱和蒸气压（kPa,110ºC）：未确定 13. 燃烧热（KJ/mol）：未确定 14. 临界温度（ºC）：未确定 15. 临界压力（KPa）：未确定 16. 油水（辛醇/水）分配系数的对数值：未确定 17. 爆炸上限（%,V/V）：未确定 18. 爆炸下限（%,V/V）：未确定 19. 溶解性：未确定 |
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Section1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE Product identifiers : Tolylene-α,4-diisocyanate Product name CAS-No.: 99741-73-8 Section2. HAZARDS IDENTIFICATION Classification of the substance or mixture Classification according to Regulation (EC) No 1272/2008 [EU-GHS/CLP] Acute toxicity, Inhalation (Category 2) Skin irritation (Category 2) Eye irritation (Category 2) Skin sensitization (Category 1) Carcinogenicity (Category 2) Specific target organ toxicity - single exposure (Category 3) Classification according to EU Directives 67/548/EEC or 1999/45/EC Very toxic by inhalation. Irritating to eyes, respiratory system and skin. May cause sensitization by inhalation and skin contact. Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. Limited evidence of a carcinogenic effect. Label elements Labelling according Regulation (EC) No 1272/2008 [CLP] Pictogram Signal wordDanger Hazard statement(s) Causes skin irritation. May cause an allergic skin reaction. Causes serious eye irritation. Fatal if inhaled. May cause respiratory irritation. Suspected of causing cancer. Precautionary statement(s) Do not breathe dust/ fume/ gas/ mist/ vapours/ spray. Wear protective gloves. Wear respiratory protection. P305 + P351 + P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/ physician. Supplemental Hazardnone Statements According to European Directive 67/548/EEC as amended. Hazard symbol(s) R-phrase(s) R26Very toxic by inhalation. R36/37/38Irritating to eyes, respiratory system and skin. R42/43May cause sensitization by inhalation and skin contact. R52/53Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R40Limited evidence of a carcinogenic effect. S-phrase(s) S23Do not breathe vapour. S36/37Wear suitable protective clothing and gloves. S45In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). S61Avoid release to the environment. Refer to special instructions/ Safety data sheets. Other hazards Lachrymator. Section3. COMPOSITION/INFORMATION ON INGREDIENTS Substances Formula: C9H6N2O2 Molecular Weight: 174,16 g/mol ComponentConcentration Tolylene-α ,4-diisocyanate CAS-No.99741-73-8- Section4. FIRST AID MEASURES Description of first aid measures General advice Consult a physician. Show this safety data sheet to the doctor in attendance. If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. Most important symptoms and effects, both acute and delayed burning sensation, Cough, wheezing, laryngitis, Shortness of breath, Headache, Nausea, Vomiting, spasm, inflammation and edema of the larynx, spasm, inflammation and edema of the bronchi, pneumonitis, pulmonary edema Indication of any immediate medical attention and special treatment needed no data available Section5. FIREFIGHTING MEASURES Extinguishing media Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Special hazards arising from the substance or mixture Carbon oxides, nitrogen oxides (NOx) Advice for firefighters Wear self contained breathing apparatus for fire fighting if necessary. Further information no data available Section6. ACCIDENTAL RELEASE MEASURES Personal precautions, protective equipment and emergency procedures Wear respiratory protection. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Methods and materials for containment and cleaning up Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed containers for disposal. Reference to other sections For disposal see section 13. Section7. HANDLING AND STORAGE Precautions for safe handling Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. Normal measures for preventive fire protection. Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Recommended storage temperature: 2 - 8 °C Specific end uses no data available Section8. EXPOSURE CONTROLS/PERSONAL PROTECTION Control parameters Components with workplace control parameters Exposure controls Appropriate engineering controls Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product. Personal protective equipment Eye/face protection Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Body Protection Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Section9. PHYSICAL AND CHEMICAL PROPERTIES Information on basic physical and chemical properties a) AppearanceForm: clear, liquid Colour: colourless b) Odourno data available c) Odour Thresholdno data available d) pHno data available e) Melting point/freezingMelting point/range: 20 °C point f) Initial boiling point and 152 °C at 25 hPa boiling range g) Flash point110 °C - closed cup h) Evaporation rateno data available i) Flammability (solid, gas) no data available j) Upper/lowerLower explosion limit: 9 %(V) flammability or explosive limits k) Vapour pressure0,04 hPa at 25 °C l) Vapour density6,01 - (Air = 1.0) m) Relative density1,226 g/cm31,218 g/cm3 n) Water solubilityno data available o) Partition coefficient: n-no data available octanol/water p) Autoignitionno data available temperature q) Decompositionno data available temperature r) Viscosityno data available s) Explosive propertiesno data available t) Oxidizing propertiesno data available Other safety information no data available Section10. STABILITY AND REACTIVITY Reactivity no data available Chemical stability no data available Possibility of hazardous reactions no data available Conditions to avoid Heat. Incompatible materials Strong oxidizing agentsAlcohols, Strong bases, Amines, acids, Strong oxidizing agents Hazardous decomposition products Other decomposition products - no data available Section11. TOXICOLOGICAL INFORMATION Information on toxicological effects Acute toxicity no data available Skin corrosion/irritation no data available Serious eye damage/eye irritation no data available Respiratory or skin sensitization May cause allergic skin reaction. Germ cell mutagenicity no data available Carcinogenicity Limited evidence of carcinogenicity in animal studies IARC:No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC. Reproductive toxicity no data available Specific target organ toxicity - single exposure Inhalation - May cause respiratory irritation. Specific target organ toxicity - repeated exposure no data available Aspiration hazard no data available Potential health effects InhalationMay be fatal if inhaled. Causes respiratory tract irritation. IngestionMay be harmful if swallowed. SkinMay be harmful if absorbed through skin. Causes skin irritation. EyesCauses serious eye irritation. Signs and Symptoms of Exposure burning sensation, Cough, wheezing, laryngitis, Shortness of breath, Headache, Nausea, Vomiting, spasm, inflammation and edema of the larynx, spasm, inflammation and edema of the bronchi, pneumonitis, pulmonary edema Additional Information RTECS: Not available Section12. ECOLOGICAL INFORMATION Toxicity no data available Persistence and degradability no data available Bioaccumulative potential no data available Mobility in soil no data available Results of PBT and vPvB assessment no data available Other adverse effects Harmful to aquatic life. Section13. DISPOSAL CONSIDERATIONS Waste treatment methods Product Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed professional waste disposal service to dispose of this material. Contaminated packaging Dispose of as unused product. Section14. TRANSPORT INFORMATION UN number ADR/RID: 2078IMDG: 2078IATA: 2078 UN proper shipping name ADR/RID: TOLUENE DIISOCYANATE IMDG: TOLUENE DIISOCYANATE IATA:Toluene diisocyanate Transport hazard class(es) ADR/RID: 6.1IMDG: 6.1IATA: 6.1 Packaging group ADR/RID: IIIMDG: IIIATA: II Environmental hazards ADR/RID: noIMDG Marine pollutant: noIATA: no Special precautions for user no data available Section15. REGULATORY INFORMATION This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006. Safety, health and environmental regulations/legislation specific for the substance or mixture no data available Chemical Safety Assessment SECTION 16 - ADDITIONAL INFORMATION N/A |
| 危害码 (欧洲) | T+ |
|---|---|
| 危险品运输编码 | UN 2078 6.1/PG 2 |
| 海关编码 | 2929109000 |
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99741-73-8 |
| 文献：Siefken Justus Liebigs Annalen der Chemie, 1949 , vol. 562, p. 75,1114 |
| 海关编码 | 2929109000 |
|---|---|
| 中文概述 | 2929109000. 其他异氰酸酯. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0% |
| 申报要素 | 品名, 成分含量, 用途 |
| Summary | 2929109000. other isocyanates. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |