20320-59-6

• 常用中文名：苯乙酰丙二酸二乙酯
• 常用英文名：Diethyl(phenylacetyl)malonate
• CAS号：20320-59-6
• 分子式：C₁₅H₁₈O₅
• 分子量：278.30000
• 发布时间：2018-03-23 08:00:00
• 更新时间：2026-07-01 10:20:57
• 有机合成中间体。
   

名称

• 中文名: 苯乙酰丙二酸二乙酯
• 英文名: diethyl 2-(2-phenylacetyl)propanedioate
• 中文别名: 二乙基丙二酸酯(苯乙酰); BMK淡黄色油; 丙二酸二乙酯(苯乙酰基); 2 -二乙酯(2-PHENYLACETYL); BMK 液体; 二乙基(苯乙酰)丙二酸酯; BMK 苯乙酰丙二酸二乙酯; 丙二酸(苯基乙酰基)二乙酯
• 英文别名: phenylacetyl-malonic acid diethyl ester; 20320 59 6; Diethyl(phenylacetyl)malonate(BMK Oil); Phmaceutical intermediates Diethyl(phenylacetyl); Diethyl(phenylacetyl)malonate,new bmk 20-6 Wickr jane8886; phenylacetyl)malonate, new bmk oil; Phmaceutical Intermediate BMK OIL; diethyl 2-(2-phenylacetyl)propanedioate wickr bettyml; Diethyi(phenylacetyl)malonate; BMK Diethyl(phenylacetyl)malonate; new p; BMK Glycidic Acid Diethyl(phenylacetyl)malonate; Diethyl(phenylacetyl)malonate bmk oil pmk oil; White Powder New P Phmaceutical ade; Diethyl(phenylacetyl)malonate china; 2-(2-phenylacetyl)propanedioate; Phenylacetylmalonic acid ethylester; New BMK Oil; BMK Oil/powder; White Powder Diethyl(phenylacetyl)malonate; New BMK Oil Diethyl(phenylacetyl)malonate; BMK Oil Diethyl( phenylacetyl) Malonate; Propanedioic; Diethyl 2-(2-phenylacetyl)propanedioate Phmaceutical ade; Phmaceutical intermediates Diethyl(phenylacetyl)malonate; High Purity Propanedioic acid, 2-(2-phenylacetyl)-, 1,3-diethyl ester; Propanedioic acid, 2-(2-phenylacetyl)-, 1,3-diethyl ester; iethyl2-(2-phenylacetyl)propanedioate; diethyl 2-(2-phenylacetyl)propanedioatec; Phenylacetylmalonsaeurediethylester; new bmk 20-6; Diethyl(phenylacetyl)malonate Oil Powder; bmk Lliquid oil; Cas 20-6; Diethyl 2-(2-phenylacetyl)propanedioate Purity; Diethyl(phenylacetyl)malonate(new bmk); Phenylacetyl-malonsaeure-diaethylester; Diethyl(phenylacetyl)malonate White Powder; bmk oil wickr:bellakmbk; Diethyl(phenylacetyl)malonate stocks; Diethyl(phenylacetyl)malonate(BMK); Propanedioic acid, (phenylacetyl)-, diethyl ester; Diethyl(phenylacetyl)malonate lge stock; Diethyl(phenylacetyl)malonate (New BMK oil )

物化性质

• 分子式: C₁₅H₁₈O₅
• 分子量: 278.30000
• 精确质量: 278.11500
• PSA: 69.67000
• LogP: 1.54060

安全

• 海关编码: 2918300090

合成路线

103-80-0 105-53-3 ~91% 20320-59-6

文献：Jung, Jae C.; Watkins, E Blake; Avery, Mitchell A. Synthetic Communications, 2002 , vol. 32, # 24 p. 3767 - 3777

64-17-5 74965-87-0 ~% 20320-59-6

文献：ANNJI PHARMACEUTICAL CO., LTD.; Chern, Ji-Wang; Jagtap, Ajit Dhananjay; Wang, Hsiao-Chun; Chen, Grace Shiahuy Patent: US2013/281451 A1, 2013 ; Location in patent: Paragraph 0283 ;

570-08-1 ~% 20320-59-6

文献：Jung, Jae C.; Watkins, E Blake; Avery, Mitchell A. Synthetic Communications, 2002 , vol. 32, # 24 p. 3767 - 3777

137786-67-5 ~% 20320-59-6

文献：Jung, Jae C.; Watkins, E Blake; Avery, Mitchell A. Synthetic Communications, 2002 , vol. 32, # 24 p. 3767 - 3777

2033-24-1 ~% 20320-59-6

文献：ANNJI PHARMACEUTICAL CO., LTD.; Chern, Ji-Wang; Jagtap, Ajit Dhananjay; Wang, Hsiao-Chun; Chen, Grace Shiahuy Patent: US2013/281451 A1, 2013 ;

103-80-0 ~% 20320-59-6

文献：ANNJI PHARMACEUTICAL CO., LTD.; Chern, Ji-Wang; Jagtap, Ajit Dhananjay; Wang, Hsiao-Chun; Chen, Grace Shiahuy Patent: US2013/281451 A1, 2013 ;

105-53-3 ~% 20320-59-6

文献：Metzner Justus Liebigs Annalen der Chemie, 1897 , vol. 298, p. 379

上下游产品

上游产品  7
103-80-0 105-53-3 64-17-5 74965-87-0
570-08-1 137786-67-5 2033-24-1
下游产品  6
103-82-2 141-82-2 105-53-3 103-79-7
6843-89-6 621-06-7

制备

将邻苯二甲酸二乙酯和金属钠共蒸的无水乙醇，滴加到丙二酸二乙酯、四氯化碳和镁的混合物中，加热使反应开始，控制温度使反应平缓。然后加入无水乙醚，加热1h，将苯乙酰氯的乙醚溶液加入（缓缓加入，不使反应过于激烈）。反应毕，冷却加水，分出油层，减压蒸去乙醚，得苯乙酰丙二酸二乙酯。 

海关

海关编码	2918300090
中文概述	2918300090 其他含醛基或酮基不含其他含氧基羧酸（包括酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%