139481-69-9

• 常用中文名：坎地沙坦甲酯
• 常用英文名：Candesartan Methyl Ester
• CAS号：139481-69-9
• 分子式：C₂₅H₂₂N₆O₃
• 分子量：454.5
• 发布时间：2018-07-25 11:19:38
• 更新时间：2026-07-09 14:22:42

名称

• 中文名: 2-乙氧基-1-[[(2’-(1H-四唑-5-基)联苯-4-基)甲基]苯并咪唑]-7-甲酸乙酯
• 英文名: Methyl 1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate
• 中文别名: (1H-四唑-5-基)联苯-4-基)甲基]苯并咪唑]-7-甲酸乙酯; 2-乙氧基-1-[[(2'-(1H-四唑-5-基)联苯-4-基)甲基]苯并咪唑]-7-甲酸甲酯(坎地沙坦酯杂质); 2-乙氧基-1-[[(2'-(1H-四唑-5-基)联苯-4-基)甲基]苯并咪唑]-7-甲酸甲酯; 坎地沙坦中间体甲酯C7; 1-[[2'-(5-四唑基)-4-联苯基]甲基]-2-乙氧基苯并咪唑-7-甲酸甲酯; 坎地沙坦酯中间体(甲酯C7); 坎地沙坦CILEXETIL 杂质I; 坎地沙坦酯杂质; 2-乙氧基-1-[[(2'-(1H-四唑-5-基)联苯-4-基)甲基]苯并咪唑]-7-甲酸乙酯; 坎地沙坦C7甲酯; 坎地沙坦酯中间体甲酯C7; 坎地沙坦酯杂质I; 2-乙氧基-1-[[(2`-(1H-四唑-5-基)联苯-4-基)甲基]苯并咪唑]-7-甲酸乙酯; 坎地沙坦杂质 7; 坎地沙坦西拉替尔杂质I; 坎地沙坦酯中间体C7; 坎地沙坦西酯 杂质 I; 坎地沙坦酯杂质9(坎地沙坦酯杂质I); 2-乙氧基-1-[[(2'; 甲酯C7; 坎地沙坦酯中间体 C7; 2-乙氧基-1-[[(2-(1H-四唑-5-基)甲基]苯并咪唑]-7-羧酸乙酯; 2-乙氧基-1-[[(2'-(1H-四唑-5-基)联苯-4-基)甲基]苯并咪唑]-7-甲酸乙酯、坎地沙坦酯中间体(C8)
• 英文别名: Methyl 1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)-methyl)-2-ethoxy-1H-benzo[d]imidazole-7; Candestan Cilexetil Impurity 9(Candestan Cilexetil Impurity I); Candestan Impurity-I (methyl ester); Candestan Cilexetil Impurity I (Candestan Methyl Ester); Methyl 2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-cboxylate (Candestan Methyl Ester); Methyl-2-Ethoxy-1-[[(2'-(1h-Tetrazol-5-Yl)Biphenyl-4-Yl)Meth; 1H-Benzimidazole-7-cboxylic acid, 2-ethoxy-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, methyl ester; thyl-2-ethoxy-1-[[2'-(1Htetrazol-5-yl-)methyl]benzimidazole]-7-cboxylate; methyl 1-((2,-(1H-tetrazol-5-yl)-[1,1,-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-cboxylate; Methyl 1-[[2’-(5-Tetrazolyl)-4-biphenylyl]methyl]-2-ethoxybenzimidazole-7-cboxylate; Candesartan Cilexetil Impurity 9; Candestan Methyl Ester; ETHYL2-ETHOXY-1-[[2'-(1H-TETRAZOL-5-YL)METHYL]BENZIMIDAZOLE-7-CBOXYLATE; Ethyl-2-Ethoxy-1-[[(2'-(1h-Tetrazol-5-Yl)Biphenyl-4-Yl)Methyl]Benzimidazole]-7-Cboxylate; Candestan methyl ester impurity; thyl-2-ethoxy-1-[[2’-(1Htetrazol-5-yl-)methyl]benzimidazole]-7-cboxylate; Methyl 1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)-methyl)-2-ethoxy-1H-benzo[d]imidazole-7-ca; 2-ethoxy-4-ethyl-1-{[4-phenyl-3-(1H-1,2,3,4-tetrazol-5-yl)phenyl]Methyl}-1H-1,3-benzodiazole-7-cboxylate; Methyl 1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-cboxylate; Candestan Cilexetil IMpurity I; Methyl 2-ethoxy-1-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]benzoimidazole-7-cboxylate; candestan cilexetil impurity1361; candestan methyl ester imp; Candestan Impurity 7; 2-Ethoxy-1-[[2'-(2H-Tetrazol-5-yl)[1,1'-Biphenyl]-4-yl]methyl]-1H-Benzimidazole-7-cboxylicacidMethylEster; Candestan Cilexetil Impurity IQ: What is Candestan Cilexetil Impurity I Q: What is the CAS Number of Candestan Cilexetil Impurity I Q: What is the storage condition of Candestan Cilexetil Impurity I Q: What e the applications of Candestan Cilexetil Impurity I; Methyl 1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-cboxylate (Candestan Cilexetil Impurity); Methyl 2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-cboxylate (Cande; CANDESTAN INTERMEDIATES(METHYL ESTER C7); Candestan Cilexetil Impurity 9 Impurity I); 2-Ethoxy-1-[[2-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-cboxylic acid methyl ester; methyl 2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-cboxylate; 2-Ethoxy-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]Methyl]-1H-benziMidazole-7-cboxylic Acid Methyl Ester

物化性质

• 密度: 1.357g/cm3
• 沸点: 704.488ºC at 760 mmHg
• 分子式: C₂₅H₂₂N₆O₃
• 分子量: 454.5
• 闪点: 379.861ºC
• 精确质量: 454.17533859
• PSA: 107.81000
• LogP: 4.50710
• 外观性状: 粉末
• 蒸汽压: 0mmHg at 25°C
• 折射率: 1.687
• 储存条件: 2-8℃，避光，惰性气体

安全

• 危害码 (欧洲): Xi

合成路线

139481-44-0 ~99% 139481-69-9

文献：Kubo, Keiji; Kohara, Yasuhisa; Imamiya, Eiko; Sugiura, Yoshihiro; Inada, Yoshiyuki; et al. Journal of Medicinal Chemistry, 1993 , vol. 36, # 15 p. 2182 - 2195

21606-04-2 ~% 139481-69-9

文献：Journal of Medicinal Chemistry, , vol. 36, # 15 p. 2182 - 2195

73833-13-3 ~% 139481-69-9

文献：Journal of Medicinal Chemistry, , vol. 36, # 15 p. 2182 - 2195

603-11-2 ~% 139481-69-9

文献：Journal of Medicinal Chemistry, , vol. 36, # 15 p. 2182 - 2195

57113-90-3 ~% 139481-69-9

文献：Journal of Medicinal Chemistry, , vol. 36, # 15 p. 2182 - 2195

136304-78-4 ~% 139481-69-9

文献：Journal of Medicinal Chemistry, , vol. 36, # 15 p. 2182 - 2195

139481-28-0 ~% 139481-69-9

文献：Journal of Medicinal Chemistry, , vol. 36, # 15 p. 2182 - 2195

856414-36-3 ~% 139481-69-9

文献：Journal of Medicinal Chemistry, , vol. 36, # 15 p. 2182 - 2195

139481-38-2 ~% 139481-69-9

文献：Journal of Medicinal Chemistry, , vol. 36, # 15 p. 2182 - 2195