57113-90-3

• 常用中文名：2-(叔丁氧羰基氨基)-3-硝基苯甲酸甲酯
• 常用英文名：Methyl 2-(tert-Butoxycarbonylamino)-3-nitrobenzoate
• CAS号：57113-90-3
• 分子式：C₁₃H₁₆N₂O₆
• 分子量：296.27600
• 发布时间：2018-03-23 08:00:00
• 更新时间：2026-07-10 13:01:19

名称

• 中文名: 阿奇沙坦沙坦中间体甲酯C3
• 英文名: Methyl 2-(tert-Butoxycarbonylamino)-3-nitrobenzoate
• 中文别名: 2-(叔丁氧基甲酰胺)-3-硝基苯甲酸甲酯; 甲酯C3; 阿齐沙坦杂质; 2-叔丁氧酰氨基-3-硝基苯甲酸甲酯; 阿齐沙坦杂质95; 阿齐沙坦INT J 阿齐沙坦-A10; 坎地沙坦酯(甲酯C3); 坎地沙坦中间体 C3 甲酯; 2-(n-叔丁氧基羰基氨基)-3-硝基苯甲酸甲酯; 2-叔丁氧酰基-3-硝基苯甲酸甲酯; 2-(叔丁氧基-2-甲酰胺)-3-硝基苯甲酸甲酯; 阿齐沙坦杂质 51; 坎地沙坦酯中间体 (甲酯C3)
• 英文别名: METHYL 2-([(1,1-DIMETHYLETHOXY)carbonyl]AMINO)-3-NITROBENZOATE; Methyl 2-[(tert-butoxycbonyl)amino]-3-nitroben; Methyl 2-(tert-Butoxycbonylamino)-3-nitrobenzoate; 2-[[(1,1-DiMethylethoxy)carbonyl]amino]-3-nitrobenzoic Acid Methyl Ester; 2-([(1,1-Dimethylethoxy)carbonyl]Amino)-3-Nitrobenzoate; METHYL-2-[(T-BOC)-AMINO]-3-NITROBENZOATE; Azilstan Impurity; 2-(Boc-amino)-3-nitrobenzoic Acid Methyl Ester; Methyl 2-(Boc-amino)-3-nitrobenzoate; Methyl 2-[(2-methylpropan-2-yl)oxycbonylamino]-3-nitrobenzoate; BENZOIC ACID, 2-[[(1,1-DIMETHYLETHOXY)carbonyl]AMINO]-3-NITRO-METHYL ESTER; methyl 2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-nitrobenzoate; 2-tertbutoxycbonylmino-3-nitrobenzoate methyl; TIANFU-CHEM - BENZOIC ACID, 2-[[(1,1-DIMETHYLETHOXY)carbonyl]AMINO]-3-NITRO-METHYL ESTER; Methyl 2- (tert butoxy-2-formamide) -3-nitrobenzoate; methyl 2-(N-tert-butoxycbonylamino)-3-nitrobenzoate; Azilstan Impurity 51; Azilstan Impurity 95; Methyl 2- (1,1-diMethylethoxy)carbonyl -3-nitrobenzoate; Methyl-2-[Tert-butoxycbonyl amino-3-nitrobenzoate]- (CAN2); 3-nitro-, methyl ester; 2-(tert-Butoxycbonylamino)-3-nitrobenzoic Acid Methyl Ester; Methyl-2-(tert-butoxy carbonyl amino)-3-nitro benzoate; Benzoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]; Methyl2-(tert-butoxy-2-cboxamido)-3-nitrobenzoate; methyl 2-(tert-butoxycbonyl)-3-nitrobenzoate

物化性质

• 密度: 1.298 g/cm3
• 沸点: 376.924ºC at 760 mmHg
• 熔点: 106 °C
• 分子式: C₁₃H₁₆N₂O₆
• 分子量: 296.27600
• 闪点: 181.758ºC
• 精确质量: 296.10100
• PSA: 110.45000
• LogP: 3.32460
• 外观性状: 固体;White to Yellow to Green powder to crystal
• 折射率: 1.566
• 储存条件: 室温

安全

• 海关编码: 2924299090

合成路线

21606-04-2 121-44-8 75-65-0 ~84% 57113-90-3

文献：Takeda Chemical Industries, Ltd. Patent: EP1420016 A1, 2004 ; Location in patent: Page 31-32 ;

21606-04-2 75-65-0 ~72% 57113-90-3

文献：MITSUBISHI TANABE PHARMA CORPORATION Patent: US2012/232283 A1, 2012 ; Location in patent: Page/Page column 43 ;

73833-13-3 68-12-2 75-65-0 ~% 57113-90-3

文献：WO2011/145100 A1, ; Page/Page column 5 ;

21606-04-2 ~% 57113-90-3

文献：Journal of Medicinal Chemistry, , vol. 36, # 15 p. 2182 - 2195

603-11-2 ~% 57113-90-3

文献：Journal of Medicinal Chemistry, , vol. 36, # 15 p. 2182 - 2195

73833-13-3 ~% 57113-90-3

文献：Journal of Medicinal Chemistry, , vol. 36, # 15 p. 2182 - 2195

856414-36-3 75-65-0 ~% 57113-90-3

文献：Journal of Medicinal Chemistry, , vol. 36, # 15 p. 2182 - 2195

上下游产品

上游产品  7
21606-04-2 121-44-8 75-65-0 73833-13-3
68-12-2 603-11-2 856414-36-3
下游产品  10
139481-38-2 136285-69-3 139481-59-7 139481-28-0
139481-72-4 145040-37-5 139481-44-0 139481-69-9
136304-78-4 474708-09-3

海关

海关编码	2924299090
中文概述	2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 包装
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%