168828-82-8

• 常用中文名：(5R)-3-[3-氟-4-(4-吗啡啉基)苯基]-5-羟甲基-2-恶唑烷酮
• 常用英文名：(R)-3-(3-Fluoro-4-morpholinophenyl)-5-(hydroxymethyl)oxazolidin-2-one
• CAS号：168828-82-8
• 分子式：C₁₄H₁₇FN₂O₄
• 分子量：296.294
• 发布时间：2019-01-04 07:29:57
• 更新时间：2026-07-01 06:29:54

名称

• 中文名: (5R)-3-[3-氟-4-(4-吗啡啉基)苯基]-5-羟甲基-2-恶唑烷酮
• 英文名: (R)-3-(3-Fluoro-4-morpholinophenyl)-5-(hydroxymethyl)oxazolidin-2-one
• 中文别名: 利奈唑胺DESACETAMIDE羟基杂质; 利奈唑胺标准品3-R; 3-[3-氟-4-(4-吗啉基)苯基]-5-羟甲基-(5R)-2-恶唑烷酮; 利奈唑烷杂质C; 利奈唑类脱乙酰胺羟基杂质; 5-羟甲基-2-恶唑烷酮; 利奈唑胺中间体02; (R)-N-[[3-(3-氟-4-吗啉基)苯基]-2-氧代-5-噁唑烷基]甲醇; 利奈唑胺杂质46; (R)-3-[3-氟-4-(4-吗啉基)苯基]-5-(羟甲基)噁唑烷-2-酮; 利奈唑胺去乙酰氨基羟基杂质; 利奈唑胺杂质PNU100440; 利奈唑胺中间体; (R)-3-[3-氟-4-(4-吗啡啉基)苯基]-5-羟甲基-2-恶唑烷酮; 利奈唑胺乙酰胺羟基杂质; 利奈唑胺脱乙酰胺羟基杂质; 利奈唑胺羟甲基杂质; 利奈唑烷杂质((5R)-3- [3-氟-4-(4-吗啉基)苯基] -5-羟基甲基-2-恶唑烷酮); 利奈唑胺杂质4-(提供图谱、合成路线等); (R)-3-[3-氟-4-(4-吗啡啉基)苯基]-5-羟甲基-2-噁唑烷酮; (R)-(3-(3-氟-4-吗啉基)苯基-2-氧代-5-噁唑烷基)甲醇; (5R)-3-[3-氟-4-(4-吗啡啉基)苯基]-5-羟甲基-2-噁唑烷酮; 利奈唑胺去乙酰酰胺羟基杂质; 利奈唑胺中间体,(5R)-3-[3-氟-4-(4-吗啡啉基)苯基]-5-羟甲基-2-恶唑烷酮; 利奈唑胺杂质E; (R)-3-[3-氟-4-(4-吗啡啉基)苯基]-5-羟甲基-2-噁唑烷酮(利奈唑胺杂质); (5R)-3-[3-氟-4-(4-吗啡啉基)苯基]-5-羟甲基-2-恶唑烷酮/(5R)-3-(3-Fluoro-4-(4-morpholinyl)phenyl)-5-hydroxymethyl-2-oxazolidione; (5R)-3-[3-氟-4-(4-吗啡啉基)苯基]-5-羟甲基-2-恶唑烷酮,10 MM DMSO 溶液; (R)-[3-(3-氟-4-吗啉苯基)-2-氧-5-噁唑烷基]甲醇; 利奈唑胺杂质
• 英文别名: R-N-[[3-[3-FLUORO-4-MORPHOLINYL]PHENYL]-2-OXO-5-OXAZOLIDINYL]METHANOL; (R) - (3 - (3 -flour o - 4 - morph olinophenyl) - 2 - o xo - 5 - ox a zo lidinyl)methyl; Linezolid impurity PNU100440; (R)-3-(3-Fluoro-4-(4-morpholinyl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one; R)-5-(Hydroxymethyl)-3-(3-fluoro-4-morpholinopheny; 3-[3-fluoro-4-(4-Morpholinyl)phenyl]-5-(hydroxyMethyl)- (5R)-2-Oxazolidinone; Linezolid InterMediate; R-N-(3-FLUORO-4-MORPHOLINYLPHENYL)-2-OXO-5-OXAZOLIDINYLMETHANOL; Linezolid Impurity 15; PNU-100440, 10 mM in DMSO; (R)-3-(3-FLUORO-4-MORPHOLINOPHENYL)-5-(HYDROXYMETHYL)OXAZOLIDIN-2-ONE; (5R)-3-[3-fluoro-4 -(4-morphinyl) phenyl] -5-hydroxymethyl-2-oxazolidinone; [(R)-3-(3-Fluoro-4-Morpholinophenyl)-2-oxo-5-oxazolidinyl]Methanol; 2-Oxazolidinone, 3-[3-fluoro-4-(4-morpholinyl)phenyl]-5-(hydroxymethyl)-, (5R); (R)-3-(3-fluoro-4-morpholinophenyl); (5R)-3-(3-Fluoro-4-(4-morpholinyl)phenyl)-5-hydroxymethyl-2- 168-8; MFCD06658241; (5R)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-5-(hydroxymethyl)-1,3-oxazolidin-2-one; (5R)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-5-(hydroxymethyl)-2-oxazolindinone; Unezolld Desacetamlde Hydroxy; (5R)-3-[3-fluoro-4-(Morpholin-4-yl)phenyl]-5-(hydroxyMethyl)-1,3-oxazolidin-2-one; Linezolid Hydroxymethyl Impurity (Linezolid Desacetamide Hydroxy Impurity); (5R)-3-(3-Fluoro-4- morpholin-4-yl-phenyl)-(5R) -hydroxymethyl- oxazolidin-2-one; PNU100440,PNU; 5(R)-Hydroxymethyl-3-[3-fluoro-4-(4-morpholinyl)phenyl]oxazolidin-2-one; (5R)-3-(3-fluoro-4-morpholin-4-ylphenyl)-5-(hydroxymethyl)-1,3-oxazolidin-2-one; 2-Oxazolidinone,3-[3-fluoro-4-(4-morpholinyl)phen; Linezolid Impurity210; Linezolid Impurity ((5R)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-5-hydroxymethyl-2-oxazolidinone); PNU100440; Linezolid Hydroxy Impurity; (5R)-3-(3-Fluoro-4-Morpholin-4-yl-phenyl)-5-hydroxyMethyl-oxazolidin-2-one; (5R)-3-(3-fluoro-4-Morpholinophenyl)-5-(hydroxyMethyl)oxazolidin-2-one; (R)-3-(3-Fluoro-4-Morpholin-4-ylphenyl)-5-(hydroxyMethyl)oxazolidine-2,4-dione; (5R)-3-(3-FLUORO-4-(4-MORPHOLINYL)PHENYL)-5-HYDROXYMETHYL-2-OXAZOLIDIONE; Linezolid-003-R; Linezolid-12; (R)-3-(3-Fluoro-4-morpholinophenyl)-5-(hydroxymethyl)oxazolidin-2-one (Linezolid Impurity); (R)-N-(3-(3-FLuORO-(4-MORPHOLINYL)PHENYL)-2-OXO-5-OXAZOLIDINYL)METHANAOL MESYLATE; 3-[3-fluoro-4-(4-morpholinyl)phenyl]-5-(hydroxymethyl)oxazolidine-2,4-dione; Linezolid impurity E; (5R)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-5-(hydroxymethyl)-1,3-oxazolidin-2-one; (5R)-3-[3-FLUORO-4-(4-MORPHOLINYL)PHENYL]-5-(HYDROXYMETHYL)-2-OXAZOLIDINONE; (5R)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-5-(hydroxymethyl)-oxazolidione; 3-(3-FLUORO-4-(4-MORPHOLINYL)PHENYL)-5-HYDROXYMETHYL-(5R)-2-OXAZOLIDIONE; (5R)-3-(3-Fluoro-4-(4-morpholinyl)phenyl)-5-hydroxymethyl-2-oxazolidione; Linezolid Impurity 46; S-5-azidomethyl-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxazolidinone; Linezolid Impurity1306; (5R)-3-[3-fluoro-4 -(4-morpholine) phenyl] -5-hydroxymethyl-2-oxazolidone; (5R)-3-[3-Fluor-4-(morpholin-4-yl)phenyl]-5-(hydroxymethyl)-1,3-oxazolidin-2-on; Linezolid impurity 12/(5R)-3-(3-Fluoro-4-(4-morpholinyl)phenyl)-5-hydroxymethyl-2-oxazolidione; (5R)-3-[3-Fluoro-4-(morpholin-4-yl)phenyl]-5-(hydroxymethyl)-1,3-oxazolidin-2-one; Linezolid Hydroxymethyl Impurity; PNU-100440; (R)-[3-(3-Fluoro-4-morpholin-4-ylphenyl)-2-oxo-5-oxazolidinyl]methanol; (5R)-3-(3-Fluoro-4-(4-morpholinyl)phenyl)-5-hydroxymethyl-2; Linezolid DesacetaMide Hydroxy IMpurity; (R)-5-( hydroxy)-3(3-fluoro-4-Morpholinphenyl)oxazolidin-2-one; Linezolid hydroxymethyl imp(R-isomer); 5-hydroxymethyl-2-ox azolidione

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 494.2±45.0 °C at 760 mmHg
• 分子式: C₁₄H₁₇FN₂O₄
• 分子量: 296.294
• 闪点: 252.7±28.7 °C
• 精确质量: 296.117249
• PSA: 62.24000
• LogP: 0.63
• 外观性状: 固体
• 蒸汽压: 0.0±1.3 mmHg at 25°C
• 折射率: 1.572
• 储存条件: 2~8℃

安全

• 危害码 (欧洲): Xi
• 海关编码: 2934999090

合成路线

上下游产品

上游产品  7
60456-26-0 168828-81-7 369-34-6 2689-39-6
565176-83-2 93246-53-8 32315-10-9
下游产品  5
168828-90-8 165800-03-3 168828-84-0 168828-89-5
174649-09-3

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%