168828-81-7

• 常用中文名：(3-氟-4-吗啉-4-基苯基)氨基甲酸苄酯
• 常用英文名：(3-Fluoro-4-morpholin-4-ylphenyl)carbamic acid benzyl ester
• CAS号：168828-81-7
• 分子式：C₁₈H₁₉FN₂O₃
• 分子量：330.353
• 相关类别： 原料药 抑制剂
• 发布时间：2018-12-28 16:23:49
• 更新时间：2026-07-12 11:38:52

名称

• 中文名: (3-氟-4-吗啉-4-基苯基)氨基甲酸苄酯
• 英文名: N-Benzyloxycarbonyl-3-Fluoro-4-Morpholinoaniline
• 中文别名: 苄基3-氟-4-(4-吗啉基)苯基)氨基甲酸酯; N-(3-氟-4-吗啉基)氨基甲酸苄酯; (3-氟-4-吗啉-4-基苯基)氨基甲酸苄酯(利萘唑酮中间体); 苄基3-氟-4-(4-吗啉基)苯基)氨基甲酸叔丁酯; 3-氟-4-吗啉苯氨基甲酸苄酯; 3-氟-N-CBZ-4-(4-吗啉基)苯胺; (3-氟-4-吗啉代苯基)氨基甲酸苯甲酯; 利奈唑胺苯杂质; N-苄氧羰基-3-氟-4-吗啉基苯胺; N-苄氧羰基-3-氟-4-吗啉基苯; 3(3-氟-4-吗啉-4-基苯基)氨基甲酸苄酯; N-苄氧羰基-3-氧-4-吗啉基苯胺(中四); 利奈唑胺苄基杂质; 利奈唑胺杂质F; (3-氟-4-吗啉代苯基)氨基甲酸苄酯; 利奈唑烷中间体(中四); 利奈唑胺中间体1; (3-氟-4-吗啉-4-基苯基)氨基甲酸苄酯(利奈唑胺杂质); 利奈唑胺杂质; 利奈唑胺中间体YB-11; (3-氟-4-吗啉-4-基苯基)氨甲酸苄酯; 3-氟-4-吗啉基苯基氨基甲酸苄酯; 利奈唑胺中间体B; N-苄氧羰基-3-氧-4-吗啉基苯胺; 利奈唑胺苄杂质
• 英文别名: 3-Fluoro-N-Cbz-4-morpholinoaniline; N-BENZYLOXYCBONYL-3-FLUORO-4-MORPHOLINOANILINE; Benzyl(3-fluoro-4-morpholin-4-yl-phenyl) cbamate; N-CBOBENZOXY-3-FLUORO-4-MORPHOLINYL-ANILINE; (3-Fluoro-4-morpholin-4-ylphenyl)cbamic acid benzyl ester; (3-Fluoro-4-morpholinophenyl)cbamic Acid Benzyl Ester; N-benzyloxycarbonyl-3-fluoro-4-morpholinoaniline; Benzyl (3-Fluoro-4-morpholinophenyl)carbamate; Linezolid Benzyl IMpurity; benzyl N-(3-fluoro-4-morpholin-4-ylphenyl)carbamate; Linezolid-10; CbaMic acid, N-[3-fluoro-4-(4-Morpholinyl)phenyl]-, phenylMethyl ester; Carbamic acid, N-[3-fluoro-4-(4-morpholinyl)phenyl]-, phenylmethyl ester; Linezolid impurity F; Benzyl (3-Fluoro-4-morpholinophenyl)cbamate >; Benzyl3-(3-Fluoro-4-(morpholin-4-yl)phenyl)cbamate; N-benzyloxycbonyl-3-fluoro-4-morpholinoaniline (Linezolid Impurity); [3-Fluoro-4-(4-morpholin-4-yl)phenyl]cbamic acid benzyl ester; 3-Fluoro-4-morpholin-4-ylphenyl]cbamic acid phenylmethyl ester; (3-Fluoro-4-morpholin-4-ylphenyl) benzyl cbamate; Benzyl (3-fluoro-4-Morpholinophenyl)cbaMate; Benzyl N-(3-fluoro-4-morpholino-phenyl)cbamate; (3-Fluoro-4-morpholinophenyl)carbamic Acid Benzyl Ester; Benzyl [3-fluoro-4-(4-morpholinyl)phenyl]carbamate; [3-Fluoro-4-(4-Morpholinyl)phenyl]cbaMic Acid PhenylMethyl Ester; N-BENZYLOXYCBONYL-3-FLUORO-4-MORPHOLINOANILINE //BP; Benzyl (3-fluoro-4-morpholin-4-yl)cbamate; [3-Fluoro-4-(4-morpholinyl)phenyl]cbamic Acid; (3 - fluoro - 4 - - 4 - base phenyl) Morpholine cbaMic acid benzyl ester; Linezolid int; Benzyl 3-Fluoro-4-(4-Morpholinyl)phenyl)cbaMate; Benzyl (3-fluoro-4-morpholine-4-ylphenyl) cbamate; Linezolid Impurity 6; Linezolid intermediate Benzyl (3-fluoro-4-morpholinophenyl)cbamate; benzyl [3-fluoro-4-(morpholin-4-yl)phenyl]carbamate; Fluoro-4-(4-Morpholinyl) Benzeamine; Linezolid Impurity212; N-[3-fluoro-4-(4-morpholinyl)phenyl]cbamic acid (phenylmethyl) ester

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 451.8±45.0 °C at 760 mmHg
• 熔点: 123.0 to 127.0 °C
• 分子式: C₁₈H₁₉FN₂O₃
• 分子量: 330.353
• 闪点: 227.0±28.7 °C
• 精确质量: 330.137970
• PSA: 50.80000
• LogP: 2.87
• 外观性状: 固体;White to Almost white powder to crystal
• 蒸汽压: 0.0±1.1 mmHg at 25°C
• 折射率: 1.605
• 储存条件: 室温，密封

安全

• 危害码 (欧洲): Xi

合成路线

501-53-1 93246-53-8 ~98% 168828-81-7

文献：Yang, Bo; Shi, Luyan; Wu, Jingjing; Fang, Xiang; Yang, Xueyan; Wu, Fanhong Tetrahedron, 2013 , vol. 69, # 15 p. 3331 - 3337

501-53-1 ~91% 168828-81-7

文献：LIANHE CHEMICAL TECHNOLOGY CO., LTD. Patent: US2011/275805 A1, 2011 ; Location in patent: Page/Page column 7 ;

369-34-6 ~% 168828-81-7

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 6 p. 857 - 859

2689-39-6 ~% 168828-81-7

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 6 p. 857 - 859

350-31-2 ~% 168828-81-7

文献：WO2011/137222 A1, ;

100-00-5 ~% 168828-81-7

文献：WO2011/137222 A1, ;

上下游产品

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下游产品  6
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