57238-75-2

• 常用中文名：5-氯甲基-3-(4-氯苯基)-1,2,4-氧二唑
• 常用英文名：5-(Chloromethyl)-3-(4-chlorophenyl)-1,2,4-oxadiazole
• CAS号：57238-75-2
• 分子式：C₉H₆Cl₂N₂O
• 分子量：229.06300
• 发布时间：2019-01-02 10:24:15
• 更新时间：2024-01-09 19:29:52

名称

• 中文名: 5-氯甲基-3-(4-氯苯基)-1,2,4-氧二唑
• 英文名: 5-(Chloromethyl)-3-(4-chlorophenyl)-1,2,4-oxadiazole
• 英文别名: MFCD00119077; 5-(chloromethyl)-3-(4-chlorophenyl)-1,2,4-oxadiazole

物化性质

• 密度: 1.4 g/cm3
• 沸点: 343.8ºC at 760 mmHg
• 熔点: 60ºC
• 分子式: C₉H₆Cl₂N₂O
• 分子量: 229.06300
• 闪点: 161.7ºC
• 精确质量: 227.98600
• PSA: 38.92000
• LogP: 3.12880
• 折射率: 1.574
• 储存条件: 2-8°C， 密封， 干燥

MSDS

Name: 5-(Chloromethyl)-3-(4-chlorophenyl)-1 2 4-oxadiazole 95+% Material Safety Data Sheet Synonym: CAS: 57238-75-2 Section 1 - Chemical Product MSDS Name:5-(Chloromethyl)-3-(4-chlorophenyl)-1 2 4-oxadiazole 95+% Material Safety Data Sheet Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 57238-75-2 5-(Chloromethyl)-3-(4-chlorophenyl)-1, 95+% unlisted Hazard Symbols: C Risk Phrases: 34 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Causes burns. Potential Health Effects Eye: Causes eye burns. Skin: Causes skin burns. Ingestion: Causes gastrointestinal tract burns. Inhalation: Causes chemical burns to the respiratory tract. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Do not induce vomiting. Get medical aid immediately. Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use foam, dry chemical, or carbon dioxide. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood. Storage: Store in a cool, dry place. Store in a tightly closed container. Corrosives area. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 57238-75-2: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: off-white Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 56 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C9H6Cl2N2O Molecular Weight: 229 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Hydrogen chloride, chlorine, hydrogen cyanide, nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 57238-75-2 unlisted. LD50/LC50: Not available. Carcinogenicity: 5-(Chloromethyl)-3-(4-chlorophenyl)-1,2,4-oxadiazole - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S.* Hazard Class: 8 UN Number: 3261 Packing Group: III IMO Shipping Name: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S. Hazard Class: 8 UN Number: 3261 Packing Group: III RID/ADR Shipping Name: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S. Hazard Class: 8 UN Number: 3261 Packing group: III Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: C Risk Phrases: R 34 Causes burns. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 Wear suitable protective clothing, gloves and eye/face protection. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 57238-75-2: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 57238-75-2 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 57238-75-2 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 危害码 (欧洲): C
• 风险声明 (欧洲): 36/37/38
• 安全声明 (欧洲): 26-36/37/39
• 海关编码: 2934999090

合成路线

5033-28-3 79-04-9 ~86% 57238-75-2

文献：Dueruest, Yaar; Karaku, Hamza; Kaiser, Marcel; Tasdemir, Deniz European Journal of Medicinal Chemistry, 2012 , vol. 48, p. 296 - 304

93048-83-0 ~85% 57238-75-2

文献：Ozcan, Sevil; Kazi, Aslamuzzaman; Marsilio, Frank; Fang, Bin; Guida, Wayne C.; Koomen, John; Lawrence, Harshani R.; Sebti, Said M. Journal of Medicinal Chemistry, 2013 , vol. 56, # 10 p. 3783 - 3805

623-03-0 ~% 57238-75-2

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 2 p. 302 - 306

5033-28-3 ~% 57238-75-2

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 3 p. 609 - 612

100-47-0 ~% 57238-75-2

文献：Bioorganic and Medicinal Chemistry, , vol. 12, # 11 p. 2815 - 2824

79-04-9 5033-28-3 ~% 57238-75-2

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 2 p. 302 - 306

22118-09-8 613-92-3 ~% 57238-75-2 721428-29-1

文献：Cottrell, Denise M.; Capers, Jeffrey; Salem, Manar M.; DeLuca-Fradley, Kate; Croft, Simon L.; Werbovetz, Karl A. Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 11 p. 2815 - 2824

上下游产品

上游产品  6
5033-28-3 79-04-9 623-03-0 100-47-0
22118-09-8 613-92-3
下游产品  1
5372-40-7

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%