132335-44-5

• 常用中文名：(S)-(-)-N,N-二甲基-3-羟基-3-(2-噻吩基)丙胺
• 常用英文名：(1S)-3-(Dimethylamino)-1-(2-thienyl)-1-propanol
• CAS号：132335-44-5
• 分子式：C₉H₁₅NOS
• 分子量：185.286
• 发布时间：2018-12-24 17:00:08
• 更新时间：2024-01-02 15:47:21

名称

• 中文名: S-(-)-N,N-二甲基-3-羟基-3-(2-噻吩)丙胺
• 英文名: (S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)propanamine
• 中文别名: (s)-(-)-N,N-二甲基-3-羟基-2-噻吩基丙胺; (S)-(-)-N,N-二甲基-3-羟基-2-噻吩基丙胺; (S)-(-)-3-(二甲氨基)-1-(2-噻吩基)-1-丙醇; 6 (S)-(-)-N,N-二甲基-3-羟基-3-(2-噻吩)丙胺; (S)-3-(二甲氨基)-1-(2-噻吩基)-1-丙醇
• 英文别名: (1S)-3-(Dimethylamino)-1-(2-thienyl)propan-1-ol; (1S)-3-(dimethylamino)-1-thiophen-2-ylpropan-1-ol; (S)-2-[3-(Dimethylamino)-1-hydroxypropyl]thiophene; (S)-3-(Dimethylamino)-1-(2-thienyl)-1-propanol; (S)-(-)-N,N-dimethyl-3-hydroxy-3-(2-thienyl)propanamine; MFCD07782107; (1S)-3-(Dimethylamino)-1-(2-thienyl)-1-propanol; 2-Thiophenemethanol, α-[2-(dimethylamino)ethyl]-, (αS)-; T5SJ BYQ2N1&1 &&S Form; (S)-N,N-DIMETHYL-3- (2-THIENYL)-3-HYDROXYPROPANAMINE

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 290.1±30.0 °C at 760 mmHg
• 熔点: 78-80ºC
• 分子式: C₉H₁₅NOS
• 分子量: 185.286
• 闪点: 129.3±24.6 °C
• 精确质量: 185.087433
• PSA: 51.71000
• LogP: 0.97
• 外观性状: 固体;White to Almost white powder to crystal
• 蒸汽压: 0.0±0.6 mmHg at 25°C
• 折射率: 1.553
• 储存条件: -20°C Freezer
• 水溶解性: 可溶于：甲醇

MSDS

Section I.Chemical Product and Company Identification Chemical Name (S)-3-(Dimethylamino)-1-(2-thienyl)-1-propanol Portland OR Synonym2-Thiophenemethanol, α-[2-(dimethylamino)ethyl]-, (αS)- (CA INDEX NAME) (S)-2-[3-(Dimethylamino)-1-hydroxy-1-propyl]thiophene Chemical FormulaC9H15NOS 132335-44-5 CAS Number Section II.Composition and Information on Ingredients Chemical NameCAS Number Percent (%)TLV/PELToxicology Data (S)-3-(Dimethylamino)-1-(2-thienyl)-1-propanol132335-44-5 Min. 98.0 (GC, Not available.Not available. T) Section III. Hazards Identification Irritating to eyes and skin on contact. Inhalation causes irritation of the lungs and respiratory system. Inflammation of the Acute Health Effects eye is characterized by redness, watering, and itching. Skin inflammation is characterized by itching, scaling, reddening, or, occasionally, blistering. Follow safe industrial hygiene practices and always wear proper protective equipment when handling this compound. CARCINOGENIC EFFECTS : Not available. Chronic Health Effects MUTAGENIC EFFECTS : Not available. TERATOGENIC EFFECTS : Not available. DEVELOPMENTAL TOXICITY: Not available. Repeated or prolonged exposure to this compound is not known to aggravate existing medical conditions. Section IV.First Aid Measures Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 Eye Contact minutes. Get medical attention. Skin ContactIn case of contact, immediately flush skin with plenty of water. Remove contaminated clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention. InhalationIf the victim is not breathing, perform mouth-to-mouth resuscitation. Loosen tight clothing such as a collar, tie, belt or waistband. If breathing is difficult, oxygen can be administered. Seek medical attention if respiration problems do not improve. IngestionINDUCE VOMITING by sticking finger in throat. Lower the head so that the vomit will not reenter the mouth and throat. Loosen tight clothing such as a collar, tie, belt or waistband. If the victim is not breathing, perform mouth-to-mouth resuscitation. Examine the lips and mouth to ascertain whether the tissues are damaged, a possible indication that the toxic material was ingested; the absence of such signs, however, is not conclusive. Section V.Fire and Explosion Data Not available. Auto-Ignition FlammabilityMay be combustible at high temperature. Flammable LimitsNot available. Flash PointsNot available. Combustion ProductsThese products are toxic carbon oxides (CO, CO2), nitrogen oxides (NO, NO2), sulfur oxides (SOx). Fire Hazards Not available. Risks of explosion of the product in presence of mechanical impact: Not available. Explosion Hazards Risks of explosion of the product in presence of static discharge: Not available. Fire Fighting Media SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray, fog or foam. DO NOT use water jet. and Instructions Consult with local fire authorities before attempting large scale fire-fighting operations. Continued on Next Page (S)-3-(Dimethylamino)-1-(2-thienyl)-1-propanol Section VI.Accidental Release Measures Spill CleanupIrritating material. Use a shovel to put the material into a convenient waste disposal container. Consult federal, state, and/or local authorities for Instructions assistance on disposal. Section VII. Handling and Storage Handling and StorageIRRITANT. Keep away from heat. Mechanical exhaust required. When not in use, tightly seal the container and store in a dry, cool place. Avoid excessive heat and light. Do not breathe dust. Information Always store away from incompatible compounds such as oxidizing agents, acids. Section VIII. Exposure Controls/Personal Protection Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended Engineering Controls exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit. Splash goggles. Lab coat. Dust respirator. Boots. Gloves. Suggested protective clothing might not be sufficient; consult a Personal Protection specialist BEFORE handling this product. Be sure to use a MSHA/NIOSH approved respirator or equivalent. Exposure LimitsNot available. Section IX. Physical and Chemical Properties Solid. (Crystal, powder. White - almostSolubility Physical state @ 20°CSoluble in methanol. white.) Not available. Specific Gravity Molecular Weight185.29Partition CoefficientNot available. Boiling PointNot available.Not applicable. Vapor Pressure Melting Point77 to 81°C (170.6 to 177.8°F)Vapor DensityNot available. Not available.Not available. Refractive IndexVolatility Critical TemperatureNot available.OdorNot available. Not available.Not available. ViscosityTaste Section X.Stability and Reactivity Data This material is stable if stored under proper conditions. (See Section VII for instructions) Stability Conditions of InstabilityAvoid excessive heat and light. IncompatibilitiesReactive with oxidizing agents, strong acids. Section XI. Toxicological Information RTECS NumberNot available. Eye Contact. Ingestion. Inhalation. Routes of Exposure Not available. Toxicity Data CARCINOGENIC EFFECTS : Not available. Chronic Toxic Effects MUTAGENIC EFFECTS : Not available. TERATOGENIC EFFECTS : Not available. DEVELOPMENTAL TOXICITY: Not available. Repeated or prolonged exposure to this compound is not known to aggravate existing medical conditions. Irritating to eyes and skin on contact. Inhalation causes irritation of the lungs and respiratory system. Inflammation of the eye Acute Toxic Effects is characterized by redness, watering, and itching. Skin inflammation is characterized by itching, scaling, reddening, or, occasionally, blistering. Follow safe industrial hygiene practices and always wear proper protective equipment when handling this compound. Section XII.Ecological Information EcotoxicityNot available. Environmental FateNot available. Continued on Next Page (S)-3-(Dimethylamino)-1-(2-thienyl)-1-propanol Section XIII. Disposal Considerations Waste DisposalRecycle to process, if possible. Consult your local regional authorities. You may be able to dissolve or mix material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system. Observe all federal, state and local regulations when disposing of the substance. Section XIV. Transport Information DOT ClassificationNot a DOT controlled material (United States). PIN NumberNot applicable. Proper Shipping NameNot applicable. Packing Group (PG)Not applicable. DOT Pictograms Section XV. Other Regulatory Information and Pictograms TSCA Chemical InventoryThis product is NOT on the EPA Toxic Substances Control Act (TSCA) inventory. The following notices are required by 40 CFR 720.36 (C) for those products not on the inventory list: (EPA) (i) These products are supplied solely for use in research and development by or under the supervision of a technically qualified individual as defined in 40 CFR 720.0 et sec. (ii) The health risks of these products have not been fully determined. Any information that is or becomes available will be supplied on an MSDS sheet. WHMIS ClassificationNot available. (Canada) EINECS Number (EEC) 603-565-7 EEC Risk StatementsR36/37/38- Irritating to eyes, respiratory system and skin. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 危害码 (欧洲): Xi
• 海关编码: 2942000000

合成路线

13196-35-5 ~81% 132335-44-5

文献：Mitsubishi Rayon Co., Ltd. Patent: EP1506965 A1, 2005 ; Location in patent: Page/Page column 35 ;

5424-47-5 ~% 132335-44-5

文献：US2005/197503 A1, ; Page/Page column 4 ;

13196-35-5 ~67% 132335-49-0 132335-44-5

文献：Lonza AG Patent: WO2004/31168 A2, 2004 ; Location in patent: Page 15-16 ;

959392-20-2 ~% 132335-44-5

文献：WO2007/77580 A2, ; Page/Page column 16; 17 ;

287737-72-8 ~% 132335-44-5

文献：US2008/15363 A1, ; Page/Page column 6 ;

5424-47-5 ~% 132335-49-0 132335-44-5

文献：Tetrahedron Letters, , vol. 31, # 45 p. 7101 - 7104

88-15-3 ~% 132335-44-5

文献：Tetrahedron Letters, , vol. 31, # 45 p. 7101 - 7104

132335-49-0 ~% 132335-44-5

文献：Organic Process Research and Development, , vol. 10, # 5 p. 905 - 913

13636-02-7 ~% 132335-44-5

文献：Organic Process Research and Development, , vol. 10, # 5 p. 905 - 913

上下游产品

上游产品  6
13196-35-5 5424-47-5 287737-72-8 88-15-3
132335-49-0 13636-02-7
下游产品  8
116539-60-7 116539-58-3 132335-46-7 878757-08-5
132335-47-8 136434-34-9 116539-55-0 161005-84-1

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%