139481-72-4

• 常用中文名：三苯甲基坎地沙坦
• 常用英文名：Trityl candesartan
• CAS号：139481-72-4
• 分子式：C₄₃H₃₄N₆O₃
• 分子量：682.768
• 相关类别： 原料药 循环系统用药 抗高血压病药
• 发布时间：2018-02-24 08:00:00
• 更新时间：2026-07-10 17:30:09

名称

• 中文名: 三苯甲基坎地沙坦
• 英文名: N-Trityl Candesartan
• 中文别名: 三苯基坎地沙坦; 坎地沙坦N1-三苯甲基杂质; 三苯基坎地沙坦 C9; 基-4基 ]甲基 ]苯并咪唑-7-羧酸; N-三甲基坎地沙坦; 三基坎地坎地沙坦(C9); 2-乙氧基-1-((2'-(1-三苯甲基-1H-四唑-5-基)-[1,1'-联苯]-4-基)甲基)-1H-苯并[D]咪唑-7-羧酸; 三苯甲基坎地沙坦 中间体; N-三苯甲基坎地沙坦甲基酯甲氧基类似物; 坎地沙坦酯中间体(C9)三苯甲基坎地沙坦; 三苯甲基坎地沙坦(TCDS); 三苯甲基坎地沙坦 C9; 坎地沙坦氮三苯甲基 同系物; N-三苯甲基坎地沙坦; 三基坎地沙坦(C9); 三苯甲基坎地沙坦(坎地沙坦酯杂质); 坎地沙坦酯中间体6; 2-乙氧基-1-[[2'-(N-三苯基甲基四唑-5-基)-双苯-4-甲基]甲基]苯并咪唑-7-羧酸; 2-乙氧基-3-[[4-[2-(1-三苯甲基-1H-四唑-5-基)苯基]苯基]甲基]-3H-苯并咪唑-4-羧酸; 三丁基坎地沙坦; 三苯基坎地沙坦酯 C10; 坎地沙坦杂质 8; 氮位N-三苯基坎地沙坦; 坎地沙坦酯中间体C9; 2-乙氧基-1-((2'-(1-三苯甲基-1H-四唑-5-基)-联苯基-4-基)甲基)-1H-苯并咪唑-7-羧酸; 坎地沙坦酯杂质9
• 英文别名: Tricycliccandestan(C9); 2-ethoxy-3-[[4-[2-[1-(triphenylmethyl)-5-tetrazolyl]phenyl]phenyl]methyl]-4-benzimidazolecboxylic acid; 2-ethoxy-1-[[(2-(1-triphenylmethyl-1Htetrazol-5-yl)biphenyl-4-yl-); Trityl candestan //BP; Candestan Cilexetil Intermediate 5; Trityl candestan/2-Ethoxy-1-[[(2'-(1-triphenylmethyl-1H-tetrazol-5-yl)biphenyl-4-yl)methyl]benzimidazole-7-cboxylic acid; 2-ethoxy-1-[[(2'-(1-triphenylmethyl-1h-tetrazol-5-yl)biphenyl-4-yl)methyl]benzimidazole-7-cboxylic acid; 2-Ethoxy-1-{[2'-(1-trityl-1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylic acid; 1H-Benzimidazole-7-cboxylic acid, 2-ethoxy-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]; Trityl Candestan (C9); 2-Ethoxy-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-cboxylic Acid DISCONTINUED; 2-ETHOXY-1-[[(2-(1-TRIPHENYLMETHYL-1H-TETRAZOL-5-YL)BIPHENYL)METHYL] BENZIMIDAZOLE-7-CARBOXYLIC ACID; 2-Ethoxy-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-cboxylic acid; 2-Ethoxy-1-[[(2’-(1-triphenylmethyl-1H-tetrazol-5-yl)biphenyl-4-yl-)methyl]benzimidazole-7-cboxylicacid; TRITYL CANDESTAN ( FOR CANDESTAN CILEXETIL ); 2-Ethoxy-1-[[2-(2-Triphenylmethyl)-2H-Tetrazole-5-Yl](1,1-Biphenyl)-4-Yl]-Methyl]Benzimidazole-7-Cboylicacid; (Trityl candestan)2-Ethoxy-1-[[2-(2-Triphenyl Methyl)-2H-Tetrazole-5-YL](1,1-Biphenyl)-4-YL]Methyl]Benzimidazole-2-Cboxylic Acid; N-tityl candestan; Candesartan Cilexetil Impurity 14; 2-Ethoxy-1-[[2-[2-(Triphenylmethyl)-2H-Tetrazol-5- Yl][1,1-Biphenyl]-4-Yl]Methyl]-1H-Benzimidazole-7- Cboxylic Acid [N-Trityl Candestan]; Trityl Candesatan; Triphenyl Candestan; 2-Ethoxy-1-{[2'-(1-trityl-1H-tetrazol-5-yl)-4-biphenylyl]methyl}-1H-benzimidazole-7-carboxylic acid; 2-ETHOXY-1-[[(2-(1-TRIPHENYLMETHYL-1H-TETRAZOL-5-YL)BIPHENYL)METHYL] BENZIMIDAZOLE-7-CBOXYLIC ACID; Candestan Cilexetil Impurity 9; Candestan Impurity 8; Candestan N1-Trityl IMpurity; TritylCandestan[CandestabCilexetilIntermediates]; CANDESTAN INTERMEDIATE A; 1H-benzimidazole-7-cboxylic acid, 1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-2-ethoxy; N-Trityl Candestan; Candestan Cilexetil Impurity 14; Triphenyl candestan ester; Trityl candestan (Candestan Cilexetil Impurity); TRITYL CANDESTAN; N-trimethylcandestan; (1H)-Benzimidazole-7-cboxylicacid; 2-Ethoxy-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-c; TritylCandestan,CandestanCilexetil; 2-Ethoxy-1-[[2'-(N-triphenylmethyltetrazol-5-yl)-biphenyl-4-yl]methyl]benzimidazole-7-cboxylic acid; 2-Ethoxy-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 908.6±75.0 °C at 760 mmHg
• 熔点: 163-165ºC
• 分子式: C₄₃H₃₄N₆O₃
• 分子量: 682.768
• 闪点: 503.3±37.1 °C
• 精确质量: 682.269226
• PSA: 107.95000
• LogP: 10.15
• 蒸汽压: 0.0±0.3 mmHg at 25°C
• 折射率: 1.678
• 储存条件: Refrigerator

安全

• 危害码 (欧洲): Xi
• 海关编码: 2933990090

合成路线

76-83-5 139481-59-7 ~88% 139481-72-4

文献：Alembic Limited Patent: US2010/210852 A1, 2010 ; Location in patent: Page/Page column 5 ;

821-25-0 76-83-5 139481-59-7 ~% 139481-72-4

文献：US6177587 B1, ;

21606-04-2 ~% 139481-72-4

文献：WO2011/145100 A1, ;

57113-90-3 ~% 139481-72-4

文献：WO2011/145100 A1, ;

139481-69-9 ~% 139481-72-4

文献：WO2011/145100 A1, ;

136304-78-4 ~% 139481-72-4

文献：WO2011/145100 A1, ;

603-11-2 ~% 139481-72-4

文献：WO2011/145100 A1, ;

139481-28-0 ~% 139481-72-4

文献：WO2011/145100 A1, ;

73833-13-3 ~% 139481-72-4

文献：WO2011/145100 A1, ;

上下游产品

上游产品  10
76-83-5 139481-59-7 821-25-0 21606-04-2
57113-90-3 139481-69-9 136304-78-4 603-11-2
139481-28-0 73833-13-3
下游产品  2
145040-37-5 170791-09-0

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%