2438-38-2

• 常用中文名：环己基磺酰胺
• 常用英文名：Cyclohexane sulfonamide(7CI,8CI,9CI)
• CAS号：2438-38-2
• 分子式：C₆H₁₃NO₂S
• 分子量：163.238
• 发布时间：2018-04-16 08:00:00
• 更新时间：2024-01-09 18:09:48

名称

• 中文名: 环己基磺酰胺
• 英文名: Cyclohexanesulfonamide
• 中文别名: 环己烷磺酰胺(7CI,9CI)
• 英文别名: Zyklohexansulfamid; Cyclohexansulfonamid; WLN: L6TJ ASZW; Cyclohexanesulfonamide; cyclohexylamidosulfonic acid; Zyklohexansulfamid [German]; cyclohexylsulfonamide; Cyclohexane sulfonamide(7CI,8CI,9CI)

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 299.8±23.0 °C at 760 mmHg
• 熔点: 94-95ºC
• 分子式: C₆H₁₃NO₂S
• 分子量: 163.238
• 闪点: 135.1±22.6 °C
• 精确质量: 163.066696
• PSA: 68.54000
• LogP: 0.77
• 蒸汽压: 0.0±0.6 mmHg at 25°C
• 折射率: 1.513
• 储存条件: 2-8°C

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : GV7450000 CHEMICAL NAME : Cyclohexanesulfonamide CAS REGISTRY NUMBER : 2438-38-2 BEILSTEIN REFERENCE NO. : 2716566 LAST UPDATED : 199612 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C6-H13-N-O2-S MOLECULAR WEIGHT : 163.26 WISWESSER LINE NOTATION : L6TJ ASZW HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 80 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 90,260,1947 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 79 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold REFERENCE : ABMGAJ Acta Biologica et Medica Germanica. (Berlin, Ger. Dem. Rep.) V.1-41, 1958-82. For publisher information, see BBIADT. Volume(issue)/page/year: 13,55,1964 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 51 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia REFERENCE : ABMGAJ Acta Biologica et Medica Germanica. (Berlin, Ger. Dem. Rep.) V.1-41, 1958-82. For publisher information, see BBIADT. Volume(issue)/page/year: 20,641,1968 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 85 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold REFERENCE : ABMGAJ Acta Biologica et Medica Germanica. (Berlin, Ger. Dem. Rep.) V.1-41, 1958-82. For publisher information, see BBIADT. Volume(issue)/page/year: 13,55,1964

安全

• 危害码 (欧洲): Xi
• 海关编码: 2935009090

合成路线

4837-38-1 ~91% 2438-38-2

文献：Egleton, James E.; Thinnes, Cyrille C.; Seden, Peter T.; Laurieri, Nicola; Lee, Siu Po; Hadavizadeh, Kate S.; Measures, Angelina R.; Jones, Alan M.; Thompson, Sam; Varney, Amy; Wynne, Graham M.; Ryan, Ali; Sim, Edith; Russell, Angela J. Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 11 p. 3030 - 3054

931-51-1 ~30% 2438-38-2

文献：BRISTOL-MYERS SQUIBB COMPANY Patent: WO2005/51410 A1, 2005 ; Location in patent: Page/Page column 80 ;

88304-20-5 ~95% 2438-38-2

文献：BASF Aktiengesellschaft Patent: US4097521 A1, 1978 ;

7664-41-7 4837-38-1 ~91% 2438-38-2

文献：LABORATOIRES SERONO SA Patent: WO2008/101979 A1, 2008 ; Location in patent: Page/Page column 88 ;

2387-23-7 ~% 2438-38-2

文献：BASF Aktiengesellschaft Patent: US4117004 A1, 1978 ;

上下游产品

上游产品  5
4837-38-1 931-51-1 88304-20-5 7664-41-7
2387-23-7
下游产品  0

海关

海关编码	2935009090
中文概述	2935009090 其他磺（酰）胺. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:35.0%
申报要素	品名, 成分含量, 用途
Summary	2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%