380380-64-3

• 常用中文名：2-(2-甲基-四氮唑)-5-溴吡啶
• 常用英文名：5-Bromo-2-(2-methyl-2H-tetrazol-5-yl)-pyridine
• CAS号：380380-64-3
• 分子式：C₇H₆BrN₅
• 分子量：240.060
• 相关类别： 医药中间体 杂环化合物 吡啶类化合物 溴吡啶
• 发布时间：2018-11-25 20:51:10
• 更新时间：2026-07-23 16:51:48

名称

• 中文名: 2-甲基-5-(5-溴吡啶-2-基)四氮唑
• 英文名: 5-Bromo-2-(2-methyl-2H-tetrazol-5-yl)pyridine
• 中文别名: 特地唑胺杂质2; 泰地唑胺杂质54; 泰地唑胺中间体 A; 特地唑胺杂质12; 特地唑胺杂质50; 2-(2-甲基-四氮唑)-5-溴吡啶(特地唑胺杂质); 2-甲基-5-(5-溴吡啶-2-基)四氮唑 特地唑胺中间体(特地唑胺中间体); 5-溴-2-(2-甲基-2H-1,2,3,4-四唑-5-基)吡啶; 5-溴-2-(2-甲基-2H-四氮唑-5-基)吡啶; 磷酸泰地唑胺中间体; 2-甲基-5-(5-溴吡啶-2-基)四氮唑,奥拉西坦中间体; 5-溴-2-(2-甲基-2H-四唑-5-基)-吡啶; 2-甲基-5-(5-溴吡啶-2-基)四氮唑 , 5-bromo-2-(2-methyl-2H-tetrazol-5-yl)pyridine; 磷酸特地唑胺中间体3/2-甲基-5-(5-溴吡啶-2-基)四氮唑; 2-甲基-5-(5-溴吡啶-2-基); 5-溴-2-(2-甲基-2H-四唑-5-基)吡啶; 5-溴-2-(2-甲基四唑-5-基)吡啶; 2-(2-甲基-2H-四唑-5-基)-5-溴吡啶; 特地唑胺杂质; 2-甲基-5-(5-溴吡啶-2-基)四氮唑 特地唑胺中间体(泰地唑胺); 特地唑胺四氮唑中间体; 2-(2-甲基-四氮唑)-5-溴吡啶特地唑胺四氮唑中间体; 磷酸特地唑胺中间体3; 磷酸特地唑胺中间体; 磷酸泰地唑胺中间体3
• 英文别名: 5-bromo-2-(2-methyl-2H-tetrazol-5-yl)pyridine380-3; 5-bromo-2-(2-methyl-2H-1,2,3,4-tetrazol-5-yl)pyridine; 5-bromo-2-(2-methyl-2H-tetrazole-5-yl)pyridine(Telizolid KRM); Torezolid-11; Tedizolid Impurity 67; 2-methyl-5-(5-bromopyridine-2-yl) tetrazolium; Ethanedioicacid,monomethylester,potassiumsalt(1:3); 2-(2-Methyl-5-tetrazolyl)-5-bromopyridine; Tedizolid impurity588; Thiazole,2-bromo-10-(bromomethyl); Piperazine,6-(methylsulfonyl); 5-bromo-2-(2-methyltetrazol-5-yl)pyridine; Methyl-5- (5-bromo-2-yl) tetrazole; 5-Bromo-2-(2-methyl-2H-tetrazol-5-yl)pyridine (Torezolid Impurity); 5-Bromo-2-(2-methyl-2H-tetrazole-5-yl)pyridine; Torezolid Intermediate2; 5-BROMO-2-(2-METHYL-2H-TETRAZOL-5-YL)-PYRIDINE ISO 9001：2015 REACH; 2-Methyl-5-(5-bromopyridin-2-yl)tetrazole; Pyridine, 5-broMo-2-(2-Methyl-2H-tetrazol-5-yl); Tedizolid interMediate; 5-broMo-2-(2-Methyl-2H-tetrazol-5-yl)pyridine (c); Terazolamide impurity 12

物化性质

• 密度: 1.9±0.1 g/cm3
• 沸点: 375.2±52.0 °C at 760 mmHg
• 分子式: C₇H₆BrN₅
• 分子量: 240.060
• 闪点: 180.7±30.7 °C
• 精确质量: 238.980652
• PSA: 56.49000
• LogP: 1.51
• 蒸汽压: 0.0±0.8 mmHg at 25°C
• 折射率: 1.759
• 储存条件: 室温，干燥

安全

• 危害码 (欧洲): Xi
• 海关编码: 2933990090

合成路线

380380-60-9 74-88-4 ~% 380380-64-3 380380-63-2

文献：ASTRAZENECA AB; ASTRAZENECA UK LIMITED Patent: WO2004/56818 A1, 2004 ; Location in patent: Page 52-53 ; WO 2004/056818 A1

1374651-37-2 ~32% 380380-64-3

文献：TRIUS THERAPEUTICS; COSTELLO, Carrie, A.; SIMSON, Jaqueline, A.; DUGUID, Robert, J.; PHILLIPSON, Douglas Patent: WO2010/42887 A2, 2010 ; Location in patent: Page/Page column 15-16 ;

74-88-4 380380-60-9 ~43% 380380-64-3 380380-63-2

文献：Im, Weon Bin; Choi, Sun Ho; Park, Ju-Young; Choi, Sung Hak; Finn, John; Yoon, Sung-Hwa European Journal of Medicinal Chemistry, 2011 , vol. 46, # 4 p. 1027 - 1039

97483-77-7 ~% 380380-64-3

文献：ASTRAZENECA UK LIMITED Patent: WO2005/116023 A1, 2005 ; Location in patent: Page/Page column 67 ; WO 2005/116023 A1

18107-18-1 380380-60-9 ~% 380380-64-3 380380-63-2

文献：Clark, Richard F.; Djuric, Stevan; Ma, Zhenkun; Phan, Ly; Rupp, Michael Patent: US2004/33970 A1, 2004 ; Location in patent: Page/Page column 9 ;

624-28-2 ~% 380380-64-3

文献：Jo, Yeong Woo; Im, Weon Bin; Rhee, Jae Keol; Shim, Mi Ja; Kim, Won Bae; Choi, Eung Chil Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 22 p. 5909 - 5915

624-28-2 ~% 380380-64-3 380380-63-2

文献：Im, Weon Bin; Choi, Sun Ho; Park, Ju-Young; Choi, Sung Hak; Finn, John; Yoon, Sung-Hwa European Journal of Medicinal Chemistry, 2011 , vol. 46, # 4 p. 1027 - 1039

97483-77-7 ~% 380380-64-3 380380-63-2

文献：Im, Weon Bin; Choi, Sun Ho; Park, Ju-Young; Choi, Sung Hak; Finn, John; Yoon, Sung-Hwa European Journal of Medicinal Chemistry, 2011 , vol. 46, # 4 p. 1027 - 1039

上下游产品

上游产品  6
380380-60-9 74-88-4 1374651-37-2 97483-77-7
18107-18-1 624-28-2
下游产品  1
1220910-89-3

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%