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70-54-2生产厂家

70-54-2价格

70-54-2

70-54-2结构式
70-54-2结构式

化源商城直购

中文名 DL-赖氨酸
英文名 lysine
中文别名 (±)2,6-二氨基己酸
DL-2,6-二氨基己酸
英文别名 Lysine, DL-
MFCD00064432
(±)-Lysine
Lys
H-DL-Lys-OH
EINECS 200-740-6
[1R-(2-endo,3-exo)]-8-Methyl-3-phenyl-8-azabicyclo[3.2.1]octane-2-carboxylic Acid Methyl Ester
(±)-2,6-Diaminohexanoic Acid
DL-Lysine
LYSINE (DL)
DL-α,ε-Diaminocaproic Acid
Benzonitrile,2,6-diamino
Lysine
H-Lys-OH
描述 DL-Lysine (Lysine) 是一种合成蛋白质的 α 氨基酸。
相关类别
靶点

Km: 100-400 μM (amino acid transporter b0,+)[1]

体外研究 DL-赖氨酸(Lys)是氨基酸转运蛋白b0的高亲和力碱性氨基酸底物,其Km值范围为100-400μM[1]。
参考文献

[1]. Nguyen TV, et al. PEPT1 enhances the uptake of gabapentin via trans-stimulation of b0,+ exchange. Pharm Res. 2007 Feb;24(2):353-60.

密度 1.1±0.1 g/cm3
沸点 311.5±32.0 °C at 760 mmHg
熔点 170ºC (dec.)
分子式 C6H14N2O2
分子量 146.188
闪点 142.2±25.1 °C
精确质量 146.105530
PSA 89.34000
LogP -1.04
蒸汽压 0.0±1.4 mmHg at 25°C
折射率 1.503
储存条件

本品应密封阴凉干燥保存。

分子结构

1、 摩尔折射率:38.43

2、 摩尔体积(cm3/mol):129.9

3、 等张比容(90.2K):348.1

4、 表面张力(dyne/cm):51.5

5、 极化率(10-24cm3):15.23

计算化学

1.疏水参数计算参考值(XlogP):无

2.氢键供体数量:3

3.氢键受体数量:4

4.可旋转化学键数量:5

5.互变异构体数量:无

6.拓扑分子极性表面积89.3

7.重原子数量:10

8.表面电荷:0

9.复杂度:106

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:1

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:1

更多

1. 性状:无色结晶物

2. 密度(g/mL,25/4℃):1.12

3. 相对蒸汽密度(g/mL,空气=1):不确定

4. 熔点(ºC):170 (dec.)(lit.)

5. 沸点(ºC,常压):不确定

6. 沸点(ºC, 5.2kPa):不确定

7. 折射率:不确定

8. 闪点(ºC):不确定

9. 比旋光度(º):不确定

10. 自燃点或引燃温度(ºC):不确定

11. 蒸气压(kPa,25ºC):不确定

12. 饱和蒸气压(kPa,60ºC):不确定

13. 燃烧热(KJ/mol):不确定

14. 临界温度(ºC):不确定

15. 临界压力(KPa):不确定

16. 油水(辛醇/水)分配系数的对数值:不确定

17. 爆炸上限(%,V/V):不确定

18. 爆炸下限(%,V/V):不确定

19. 溶解性:溶于水,微溶于乙醇,不溶于乙醚

Name: DL-Lysine 98% Material Safety Data Sheet
Synonym: None known
CAS: 70-54-2
Section 1 - Chemical Product MSDS Name:DL-Lysine 98% Material Safety Data Sheet
Synonym:None known

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
70-54-2 DL-Lysine 98.0 200-740-6
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
No information found.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Non-combustible, substance itself does not burn but may decompose upon heating to produce irritating, corrosive and/or toxic fumes.
Extinguishing Media:
Substance is noncombustible; use agent most appropriate to extinguish surrounding fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.

Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Use with adequate ventilation.
Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 70-54-2: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: white
Odor: none reported
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 170 deg C
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: > 170 deg C
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C6H14N2O2
Molecular Weight: 146.19

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 70-54-2 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
DL-Lysine - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing group:

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
S 28A After contact with skin, wash immediately with
plenty of water.
S 37 Wear suitable gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 70-54-2: 0
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 70-54-2 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 70-54-2 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A
个人防护装备 Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
危害码 (欧洲) T+:Very toxic
安全声明 (欧洲) S1-S28-S45
危险品运输编码 NONH for all modes of transport
WGK德国 3
海关编码 2922411000

可通过蛋白质与碱共热所产生的蛋白质水解液中提取或用二氢吡喃为原料进行有机合成方法生产时,所得产物才为DL-赖氨酸,实际上它是等量的D-赖氨酸分子和L-赖氨酸分子混合物,两者互为光学异构体(optical isomer)。

海关编码 2922411000
中文概述 HS: 2922411000. 赖氨酸. 增值税率:17.0%. 退税率:9.0%. 监管条件:AB(入境货物通关单,出境货物通关单). 最低关税:5.0%. 普通关税:20.0%
申报要素 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装
监管条件 A.入境货物通关单 B.出境货物通关单
检验检疫 P.进境动植物、动植物产品检疫 Q.出境动植物、动植物产品检疫 M.进口商品检验
Summary HS: 2922411000. 2,6-diaminohexanoic acid. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:ab(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tarrif:5.0%. general tariff:20.0%