849727-63-5

• 常用中文名：3-(2-氯乙基)-2-甲基-9-羟基-6, 7,8,9-四氢-4H-吡啶[1,2-A]嘧啶-4-酮盐酸盐
• 常用英文名：3-(2-Chloroethyl)-2-methyl-9-hydroxy--6, 7,8,9-tetrahydro-4H-pyrido [1,2-a] pyrimidin-4-one Hcl
• CAS号：849727-63-5
• 分子式：C₁₁H₁₆Cl₂N₂O₂
• 分子量：279.16300
• 相关类别： 医药中间体 杂环化合物 吡啶类化合物 乙基吡啶
• 发布时间：2018-12-24 19:09:35
• 更新时间：2024-01-28 18:55:19

名称

• 中文名: 3-(2-氯乙基)-2-甲基-9-羟基-6, 7,8,9-四氢-4H-吡啶[1,2-A]嘧啶-4-酮盐酸盐
• 英文名: 3-(2-chloroethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one,hydrochloride
• 中文别名: 4H-吡啶并[1,2-A]嘧啶-4-酮,3-(2-氯乙基)-6,7,8,9-四氢-9-羟基-2-甲基-,单盐酸盐
• 英文别名: 3-(2-chloroethyl)-9-hydroxy-2-methyI-6,7,8,9-tetrahydro-4H-pyrido [1,2-a]pyrimidin-4-one hydrochloride; 3-(2-Chloroethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one hydrochloride; 3-(2-chloroethyl)-6,7,8,9-tetrahydro-2-methyl-9-hydroxy-4H-pyrido[1,2-a]pyrimidin-4-one hydrochloride

物化性质

• 分子式: C₁₁H₁₆Cl₂N₂O₂
• 分子量: 279.16300
• 精确质量: 278.05900
• PSA: 55.12000
• LogP: 1.96220

合成路线

849727-62-4 ~68% 849727-63-5

文献：De Smet, Koen; Van Dun, Jan; Stokbroekx, Bard; Spittaels, Tom; Schroyen, Christine; Van Broeck, Peter; Lambrechts, Julien; Van Cleuvenbergen, Dirk; Smout, Guy; Dubois, Jeroen; Horvath, Andras; Verbraeken, Jurgen; Cuypers, Jef Organic Process Research and Development, 2005 , vol. 9, # 3 p. 344 - 347

147687-17-0 ~87% 849727-63-5

文献：Xu, Weichu; Wright, George E.; Yanachkova, Milka; Yanachkov, Ivan B. Letters in Organic Chemistry, 2014 , vol. 11, # 6 p. 470 - 473

517-23-7 ~% 849727-63-5

文献：Xu, Weichu; Wright, George E.; Yanachkova, Milka; Yanachkov, Ivan B. Letters in Organic Chemistry, 2014 , vol. 11, # 6 p. 470 - 473

24016-03-3 ~% 849727-63-5

文献：Xu, Weichu; Wright, George E.; Yanachkova, Milka; Yanachkov, Ivan B. Letters in Organic Chemistry, 2014 , vol. 11, # 6 p. 470 - 473

130049-82-0 ~44% 849727-63-5

文献：INKE, S.A. Patent: WO2009/144288 A1, 2009 ; Location in patent: Page/Page column 12-13 ;