1421-65-4

• 常用中文名：盐酸左旋多巴甲酯
• 常用英文名：L-3,4-Dihydroxyphenylalanine Methyl ester hydrochloride
• CAS号：1421-65-4
• 分子式：C₁₀H₁₄ClNO₄
• 分子量：247.676
• 发布时间：2018-12-11 16:07:55
• 更新时间：2026-07-03 16:55:46
• Melevodopa hydrochloride is a biochemical.

名称

• 中文名: L-3,4-二羟基苯基丙氨酸甲酯盐酸
• 英文名: L-DOPA Methyl Ester Hydrochloride
• 中文别名: 化合物:L-DOPA methyl ester (hydrochloride); 左旋多巴甲酯盐酸盐; L-3,4-二羟基苯丙氨酸甲酯盐酸盐; 左旋多巴杂质18; 羟基-L-酪氨酸甲酯,3; L-多巴甲酯盐酸盐; 化合物：L-DOPA methyl ester (hydrochloride); 盐酸左旋多巴甲酯R; 甲基 L -多巴 盐酸盐; 3,4-二羟基-L-苯丙氨酸甲酯盐酸盐; (S)-2-氨基-3-(3,4-二羟苯基)丙酸甲酯盐酸盐
• 英文别名: L-3,4-DIHYDROXYPHENYLALANINE METHYLESTER HYDROCHLO; methyldopa hydrochloride; Levodopa Impurity 10; Dopamine, methyl ester; methyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate,hydrochloride; Methyl 3-hydroxy-L-tyrosinate hydrochloride (1:1); methyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate hydrochloride; L -3,4-Dihydroxyphenylalanine methyl ester hydrochloride; 3-hydroxy- L-Tyrosine methyl ester, hydrochloride (1:1); Methyl L-3-(3,4-dihydroxyphenyl)alaninate hydrochloride; L-3,4-dihydroxyphenylalanine methyl*ester hydroch; METHYL L-DOPA HYDROCHLORIDE; 3,4-DIHYDROXY PHENYLALANINE METHYL ESTER HYDROCHLORIDE; L-Tyrosine, 3-hydroxy-, methyl ester, hydrochloride (1:1); 3-Hydroxy-L-tyrosine Methyl Ester Hydrochloride; 4-DIHYDROXYPHENYLALANINE METHYL ESTER HYDROCHLORIDE; Levodopa methyl ester hydrochloride L-DOPA Me ester hydrochloride; Methyl 2-amino-3-(3,4-dihydroxyphenyl); H-TYR(3-HYDROXY)-OME HCL; Levodopa methyl ester hydrochloride; L-3,4-Dihydroxyphenylalanine methyl ester hydrochloride; 2-Amino-3-(3,4-dihydroxyphenyl)-propanoic acid methylester hydrochloride; Methyl 3-Hydroxy-L-tyrosine Hydrochloride; 3,4-Dihydroxyphenyl-L-alanine methyl ester hydrochloride; LevoMet Hydrochloride; [(2S)-3-(3,4-dihydroxyphenyl)-1-methoxy-1-oxopropan-2-yl]azanium; 3-(3,4-Dihydroxyphenyl)alanine Methyl Ester Hydrochloride; L-3,4-DIHYDROXYPHENYLALANINE METHYL ESTER HYDROCHLORIDE; Melevodopa Hydrochloride; L-Tyrosine, 3-hydroxy-, methyl ester, hydrochloride; (S)-2-Amino-3-(3,4-dihydroxyphenyl)propanoic acid hydrochloride; MFCD00038958; Melevodopa; TIANFUCHEM-1-4-High purity L-3,4-DIHYDROXYPHENYLALANINE METHYL ESTER HYDROCHLORIDE in stock; (S)-Methyl 2-amino-3-(3,4-dihydroxyphenyl)propanoate hydrochloride; Nsc295453; L-3, 4-Dihydroxyphenylalanine methyleester hydrochloride; L-3,4-Dihydroxyphenylalanine methyl ester; L-DOPA Me ester hydrochloride; H-PHE(3,4-DI-HYDROXY)-OME HCL; Methyl L-DOPA hydrochloride; Hydroxy-L-tyrosine methyl ester, 3; 3,4-Dihydroxy-L-phenylalanine Methyl Ester Hydrochloride; L-DOPA Methyl Ester HCl

物化性质

• 密度: 1.322g/cm3
• 沸点: 384.4ºC at 760mmHg
• 分子式: C₁₀H₁₄ClNO₄
• 分子量: 247.676
• 闪点: 186.3ºC
• 精确质量: 247.061142
• PSA: 92.78000
• LogP: 1.64290
• 外观性状: 白色固体
• 蒸汽压: 1.86E-06mmHg at 25°C
• 储存条件: -20°C
• 计算化学:

  1.疏水参数计算参考值（XlogP）:无

  2.氢键供体数量:4

  3.氢键受体数量:5

  4.可旋转化学键数量:4

  5.互变异构体数量:18

  6.拓扑分子极性表面积92.8

  7.重原子数量:16

  8.表面电荷:0

  9.复杂度:222

  10.同位素原子数量:0

  11.确定原子立构中心数量:1

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:2

安全

• 危害码 (欧洲): Xi
• 危险品运输编码: NONH for all modes of transport
• 海关编码: 2923900090

合成路线

67-56-1 59-92-7 ~99% 1421-65-4

文献：Journal of Medicinal Chemistry, , vol. 44, # 21 p. 3488 - 3503

59-92-7 ~% 1421-65-4

文献：US5952328 A1, ; US 5952328 A

60-29-7 59-92-7 ~% 1421-65-4

文献：US5387610 A1, ;

上下游产品

上游产品  3
67-56-1 59-92-7 60-29-7
下游产品  0

海关

海关编码	2923900090
中文概述	2923900090 其他季铵盐及季铵碱。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%