358-72-5

• 常用中文名：DMAPP
• 常用英文名：GAMMA GAMMA-DIMETHYLALLYL PYROPHOSPHATE&
• CAS号：358-72-5
• 分子式：C₅H₁₂O₇P₂
• 分子量：246.09200
• 相关类别： 研究领域 代谢疾病
• 发布时间：2016-08-26 03:27:50
• 更新时间：2026-07-03 17:12:55
• DMAPP(二甲基烯丙基焦磷酸盐)是一种类异戊二烯前体。DMAPP是异戊烯基焦磷酸盐(IPP)的异构体,几乎存在于所有生命形式中[1]。

名称

• 英文名: prenyl diphosphate
• 英文别名: dimethylallyl-diphosphate; gamma,gamma-dimethylallyl pyrophosphate ammonium; 3-methylbut-2-enyl phosphono hydrogen phosphate; Diphosphoric acid, P-(3-methyl-2-buten-1-yl) ester; dimethylallyl-PPi; Dimethylallyl diphosphate; 2-Isopentenyl diphosphate; Diphosphoric acid P1-(3-methyl-2-butenyl) ester; dimethylallylpyrophosphate; (hydroxy-(3-methylbut-2-enoxy)phosphoryl)oxyphosphonic acid; Diphosphoric acid α-(3-methyl-2-butenyl) ester; 3,3-dimethylallyl pyrophosphate; Dimethylallylpyrophosphate; 3,3-dimethylallylpyrophosphate; delta2-Isopentenyl diphosphate; Prenyl diphosphate; 3-Methyl-2-butene-1-ol diphosphate; Pyrophosphoric acid α-isopentenyl ester

物化性质

• 密度: 1.557g/cm3
• 沸点: 417ºC at 760mmHg
• 分子式: C₅H₁₂O₇P₂
• 分子量: 246.09200
• 闪点: 206ºC
• 精确质量: 246.00600
• PSA: 132.91000
• LogP: 1.17890

生物活性

• 描述: DMAPP(二甲基烯丙基焦磷酸盐)是一种类异戊二烯前体。DMAPP是异戊烯基焦磷酸盐(IPP)的异构体,几乎存在于所有生命形式中[1]。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 代谢疾病
• 体外研究: DMAPP(二甲基烯丙基焦磷酸盐)是一种类异戊二烯前体。DMAPP是类异戊二烯前体生物合成的甲羟戊酸途径和MEP途径的产物。DMAPP是异戊烯基焦磷酸盐(IPP)的异构体,几乎存在于所有生命形式中。异戊烯基焦磷酸异构酶催化DMAPP和IPP之间的异构化[1]
• 参考文献:

  [1]. Wang W, et al. Bioorganometallic chemistry with IspG and IspH: structure, function, and inhibition of the [Fe(4)S(4)] proteins involved in isoprenoid biosynthesis. Angew Chem Int Ed Engl. 2014;53(17):4294-4310.

安全

• 危害码 (欧洲): T: Toxic;
• 风险声明 (欧洲): 10-23/24/25-39/23/24/25
• 安全声明 (欧洲): 7-16-36/37-45
• 危险品运输编码: UN 1230 3/PG 2
• 海关编码: 2905290000

合成路线

358-71-4 ~% 358-72-5

文献：Takagi, Motoki; Kaneda, Kazuhide; Shimizu, Tomohiro; Hayakawa, Yoichi; Seto, Haruo; Kuzuyama, Tomohisa Bioscience, Biotechnology and Biochemistry, 2004 , vol. 68, # 1 p. 132 - 137

556-82-1 ~% 358-72-5

文献：Dixit, Vyas M.; Laskovics, F. Mark; Noall, Wendy I.; Poulter, C. Dale Journal of Organic Chemistry, 1981 , vol. 46, # 9 p. 1967 - 1969

76947-02-9 870-63-3 ~77% 358-72-5

文献：Davisson, V. Jo; Woodside, Andrew B.; Neal, Timothy R.; Stremler, Kay E.; Muehlbacher, Manfred; Poulter, C. Dale Journal of Organic Chemistry, 1986 , vol. 51, # 25 p. 4768 - 4779

870-63-3 ~% 358-72-5

文献：Dixit, Vyas M.; Laskovics, F. Mark; Noall, Wendy I.; Poulter, C. Dale Journal of Organic Chemistry, 1981 , vol. 46, # 9 p. 1967 - 1969

396726-03-7 ~% 358-72-5 358-71-4

文献：Wang, Weixue; Wang, Ke; Liu, Yi-Liang; No, Joo-Hwan; Li, Jikun; Nilges, Mark J.; Oldfield, Eric Proceedings of the National Academy of Sciences of the United States of America, 2010 , vol. 107, # 10 p. 4522 - 4527

98139-35-6 ~% 358-72-5

文献：Eggerer,H. Chemische Berichte, 1961 , vol. 94, p. 177 - 185

22678-99-5 ~% 358-72-5 358-71-4

文献：Xiao, Youli; Chang, Wei-Chen; Liu, Hung-Wen; Liu, Pinghua Organic Letters, 2011 , vol. 13, # 21 p. 5912 - 5915

104715-10-8 ~% 358-72-5 358-71-4

文献：Xiao, Youli; Chang, Wei-Chen; Liu, Hung-Wen; Liu, Pinghua Organic Letters, 2011 , vol. 13, # 21 p. 5912 - 5915

10379-43-8 ~% 358-72-5

文献：Chen, Mo; Poulter, C. Dale Biochemistry, 2010 , vol. 49, # 1 p. 207 - 217

上下游产品

上游产品  7
358-71-4 556-82-1 76947-02-9 870-63-3
396726-03-7 104715-10-8 10379-43-8
下游产品  8
31524-62-6 20268-93-3 27364-71-2 106-24-1
763-10-0 98-55-5 138-86-3 6699-20-3

海关

海关编码	2905290000
中文概述	2905290000 其他不饱和一元醇。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:5.5%。普通关税:30.0%
申报要素	品名, 成分含量, 用途, 包装
Summary	2905290000 unsaturated monohydric alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%