6200-60-8

• 常用中文名：咪唑[1,2-A]吡啶-3-甲酸
• 常用英文名：Imidazo[1,2-a]pyridine-3-carboxylic Acid
• CAS号：6200-60-8
• 分子式：C₈H₆N₂O₂
• 分子量：162.145
• 发布时间：2019-01-01 00:09:34
• 更新时间：2024-01-02 20:03:16
• 下载msds

名称

• 中文名: 咪唑并[1,2-a]吡啶-3-甲酸
• 英文名: Imidazo[1,2-a]pyridine-3-carboxylic Acid
• 中文别名: 咪唑[1,2-a]吡啶-3-甲酸; 咪唑[1,2-A]吡啶-3-羧酸
• 英文别名: Imidazo[1,2-a]pyridine-3-carboxylic acid

物化性质

• 密度: 1.4±0.1 g/cm3
• 熔点: 196ºC
• 分子式: C₈H₆N₂O₂
• 分子量: 162.145
• 精确质量: 162.042923
• PSA: 54.60000
• LogP: 1.44
• 外观性状: 灰白色固体
• 折射率: 1.676
• 储存条件: 室温，干燥

MSDS

Name: Imidazo[1 2-a]pyridine-3-carboxylic acid Material Safety Data Sheet Synonym: CAS: 6200-60-8 Section 1 - Chemical Product MSDS Name:Imidazo[1 2-a]pyridine-3-carboxylic acid Material Safety Data Sheet Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 6200-60-8 Imidazo[1,2-a]pyridine-3-carboxylic ac 97+% unlisted Hazard Symbols: XI Risk Phrases: 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Irritating to eyes, respiratory system and skin. Potential Health Effects Eye: Causes eye irritation. Skin: Causes skin irritation. May be harmful if absorbed through the skin. Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed. Inhalation: Causes respiratory tract irritation. May be harmful if inhaled. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 6200-60-8: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: Off white Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 195.5 - 197 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C8H6N2O2 Molecular Weight: 162.15 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Strong oxidizing agents, reducing agents, strong bases, amines. Hazardous Decomposition Products: Carbon monoxide, oxides of nitrogen, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 6200-60-8: NJ5468000 LD50/LC50: Not available. Carcinogenicity: Imidazo[1,2-a]pyridine-3-carboxylic acid - Not listed by ACGIH, IARC, or NTP. Other: See actual entry in RTECS for complete information. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR Not regulated as a hazardous material. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XI Risk Phrases: R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 22 Do not breathe dust. S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 Wear suitable protective clothing, gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 6200-60-8: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 6200-60-8 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 6200-60-8 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : NJ5468000 CHEMICAL NAME : Imidazo(1,2-a)pyridine-3-carboxylic acid CAS REGISTRY NUMBER : 6200-60-8 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C8-H6-N2-O2 MOLECULAR WEIGHT : 162.16 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2 gm/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - muscle contraction or spasticity REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 12,122,1969

安全

• 危害码 (欧洲): Xi: Irritant;
• 海关编码: 2933990090

合成路线

504-29-0 ~% 6200-60-8

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 5 p. 1870 - 1873

123531-52-2 ~% 6200-60-8

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 5 p. 1870 - 1873

上下游产品

上游产品  2
504-29-0 123531-52-2
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274-76-0 92961-15-4

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%