144750-42-5

• 常用中文名：(S)-(O-氯苯基)-6,7-二羟噻吩[3,2-C]吡啶-5(4H)-醋酸盐酸盐
• 常用英文名：2-Methoxyethyl 1- methylethyl 2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate
• CAS号：144750-42-5
• 分子式：C₁₅H₁₅Cl₂NO₂S
• 分子量：344.3
• 发布时间：2018-09-13 14:37:54
• 更新时间：2026-06-30 23:50:42

名称

• 中文名: (S)-2-(2-氯苯基)-2-(6,7-二氢噻吩并[3,2-c]吡啶-5(4H)-基)乙酸盐酸盐
• 英文名: (S)-2-(2-Chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetic acid hydrochloride
• 中文别名: 氯吡格雷杂质I; 硫酸氢氯吡格雷杂质A; (+) - (S) - (邻氯苯基)-6,7 - 二氢噻吩并噻吩并[3,2-C〕吡啶-5(4H) - 乙酸,盐酸盐; 氯吡格雷有关物质A; 氯吡格雷杂质1HCL(氯吡格雷杂质A HCL); 硫酸氯吡格雷杂质A盐酸盐; (S)-(O-氯苯基)-6,7-二羟噻吩[3,2-C]吡啶-5(4H)-乙酸盐酸盐; 硫酸氢氯吡咯雷A; 氯吡格雷羧酸盐酸盐; 杂质A; (S)-(邻氯苯基)-6,7-二氢噻吩并[3,2-C]吡啶-5(4H)-乙酸盐酸盐; 氯吡格雷USP杂质A; ALPHA-(2-氯苯基)-6,7-二氢噻吩并[3,2-C]吡啶-5(4H)-乙酸盐酸盐; 氯吡格雷杂质A盐酸盐; 氯吡格雷杂质10盐酸盐; 氯吡格雷杂质A 盐酸盐; 氯吡格雷杂质A; 氯吡格雷酸盐酸盐; 氯吡格雷相关杂质A 标准品; (S)-2-(2-氯苯基)-2-(6,7-二氢噻吩并[3,2-C]吡啶-5(4H)-基)乙酸盐酸盐; 硫酸氢氯吡格雷EF杂质A; (2S) - (2 - 氯苯基)[6,7 - 二氢噻吩并[3,2-C〕吡啶-5(4H) - 基]乙酸; 氯吡格雷杂质Ⅰ; 氯吡格雷相关杂质A; 氯吡格雷相关化合物A盐酸盐; (S)-2-(2-氯苯基)-2-(6,7-二氢噻吩并[3,2-C]吡啶-5(4H)-基)乙酸盐酸盐(氯吡格雷杂质)
• 英文别名: Clopidoel cboxylic acid Impurity; Clopidoel Impurity 1 HCl(Clopidoel Impurity A HCl); Clopidoel Related Compound A (20 mg) ((S)-(ochlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-aceticv acid, hydrochloride); (2S)-(2-Chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetic acid hydrochloride (1:1); (S)-2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetic acid hydrochloride (Clopidoel Impurity）; (2S)-(2-Chlorophenyl)[6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]acetic Acid Hydrochloride (Clopidoe; Clopidoel Related Compound A ((+)-(S)-(o-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-ace; Clopidoel Hydrogen Sulfate Impurity A as Hydrochloride; Clopidoel Impurity 10 HCl; Clopidoel ImpurityCl; Clopidoel RC A; Clopidoel Related Compound A /imp A; Clopidogrel Impurity 1; Thieno[3,2-c]pyridine-5(4H)-acetic acid, α-(2-chlorophenyl)-6,7-dihydro-, methyl ester, (αR)-, sulfate (1:1); Clopidoel Related Compound A as Hydrochloride; Clopidoel Impurity A（）; Clopidoel Impurity 2/Clopidoel Impurity A HCl/(S)-Clopidoel Acid Hydrochloride/(S)-2-(2-Chlorophenyl)-2-(6,7-dihydrothieno-[3,2-c]pyridin-5(4H)-yl)acetic acid hydrochloride; Clopidogrel Related Compound C; Clopidogrel Related Compound A; (S)-2-(2-Chlorophenyl)-2-(6,7-dihydrothieno-[3,2-c]pyridin-5(4H)-yl)acetic acid hydrochloride; Methyl (2R)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate sulfate (1:1); alpha-(2-Chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetic acid hydrochloride; (S)-(2-Chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetic acid hydrochloride; (+)-(S)-(o-Chlorophenyl)-6,7-dihydrothieno3,2-yridine-5(4H)-acetic acid hydrochloride; Clopidoel Cboxylic Acid Hydrochloride; (2S)-(2-Chlorophenyl)[6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]acetic Acid Hydrochloride (Clopidoel Acid Hydrochloride); Clopidogrel Related CoMpound A,(S)-(o-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetic acid, hydrochloride; Thieno[3,2-c]pyridine-5(4H)-acetic acid, α-(2-chlorophenyl)-6,7-dihydro-, (αS)-, hydrochloride (1:1); Clopidoel Impurity A HCl; CLOPIDOEL RELATED COMPOUND A (20 MG) ((S)-(O-CHLOROPHENYL)-6,7-DIHYDROTHIENO[3,2-C]PYRI-DINE-5(4H)-ACETIC ACID, HYDROCHLORIDE); Thieno[3,2-c]pyridine-5(4H)-acetic acid, α-(2-chlorophenyl)-6,7-dihydro-, hydrochloride (1:1), (αS); Clopidoel IMpurity-A; (2S)-(2-Chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetic acid; Clopidoel acid hydrochloride; Clopidoel Impurity A Hydrochloride; methyl (2R)-2-(2-chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate,sulfuric acid; (S)-(o-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetic acid; Clopidoel Related Compound A (H0M124); Clopidoel-related impurities A; (S)-(o-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetic acid, hydrochloride; Clopidoel Cboxylic Acid Hydrochloride Salt; Clopidoel I; Clopidoel Related CoMpound A; Clopidoel impurity-A RC A)

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 447.3±45.0 °C at 760 mmHg
• 分子式: C₁₅H₁₅Cl₂NO₂S
• 分子量: 344.3
• 闪点: 224.3±28.7 °C
• 精确质量: 343.0200553
• PSA: 68.78000
• LogP: 3.77
• 蒸汽压: 0.0±1.1 mmHg at 25°C
• 折射率: 1.658
• 储存条件: 室温，保存在惰性气体中

安全

• 符号: GHS07
• 信号词: Warning
• 危害声明: H302
• 危险品运输编码: NONH for all modes of transport
• 海关编码: 2934999090

合成路线

144457-28-3 ~90% 144750-42-5

文献：HANMI PHARM. CO., LTD. Patent: WO2006/137628 A1, 2006 ; Location in patent: Page/Page column 13 ;

113665-84-2 ~% 144750-42-5

文献：WO2008/34912 A2, ; Page/Page column 51 ;

上下游产品

上游产品  2
144457-28-3 113665-84-2
下游产品  1
113665-84-2

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%