107007-95-4

• 常用中文名：1-脱甲基格拉司琼(格拉司琼杂质B)
• 常用英文名：granisetron impurity b
• CAS号：107007-95-4
• 分子式：C₁₇H₂₂N₄O
• 分子量：298.38300
• 相关类别： 分析化学 标准品 药典标准品和杂志标准品
• 发布时间：2018-12-27 22:15:28
• 更新时间：2026-07-18 15:53:11

名称

• 中文名: 向内-N-(9-甲基-9-氮杂双环[3.3.1]壬烷-3基)-1H-吲唑-3-甲酰胺
• 英文名: N-(9-methyl-9-azabicyclo[3.3.1]nonan-3-yl)-1H-indazole-3-carboxamide
• 中文别名: 1-去甲格拉司琼; N-(1R,3R,5S)-9-甲基-9-氮杂双环[3.3.1]壬-3-基)-1H-吲唑-3-甲酰胺 (格拉司琼杂质); 格拉斯琼杂质B; 格拉司琼杂质2(格拉司琼杂质B); 格拉司琼相关物质B 标准品; 格拉司琼杂质B; 格拉司琼相关物质B; 格拉司琼相关化合物B; 盐酸格拉司琼杂质 B; 盐酸格拉司琼杂质B; N-[(3-内型)-9-甲基-9-氮杂双环[3.3.1]壬烷-3-基]-1H-吲唑-3-甲酰胺; 格拉司琼杂质3
• 英文别名: 1-Desmethyl anisetron; anisetron Related Compound B (N-[(1R,3r,5S)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-c; Imp. B :N-[(1R,3r,5S)-9-Methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-cboxamide; ANISETRON IMPURITY B; N-[(3-endo)-9-Methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-cboxamide; N-((1R,3r,5S)-9-Methyl-9-azabicyclo[3.3.1]nonan-3-yl)-1H-indazole-3-cboxamide anisetron Impurity); 1-Desmethyl anisetron anisetron Impurity B); anisetron Hydrochloride Impurity B; N-[(1R,3r,5S)-9-Methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-cboxaMide; anisetron Related Compound B; M-1285; anisetron Impurity 2（anisetron Impurity B）; endo-N-(9-Methyl-9-azabicyclo[3.3.1]non-3-yl)-1H-indazole-3-cboxamide; N-[(1R,5S)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]-1H-indazole-3-cboxamide; anisetron Related Compound B (15 mg) (N-[(1R,3r,5S)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-cboxamide); 1-Desmethyl anisetron anisetron Impurity β); 1H-Indazole-3-cboxamide, N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]; Granisetron Impurity B; Granisetron impurity B

物化性质

• 熔点: 217-219℃
• 分子式: C₁₇H₂₂N₄O
• 分子量: 298.38300
• 精确质量: 298.17900
• PSA: 61.02000
• LogP: 2.63680

安全

• 危险品运输编码: NONH for all modes of transport
• 海关编码: 2934999090

合成路线

76272-41-8 4498-67-3 ~98% 107007-95-4

文献：Vernekar, Sanjeev Kumar V.; Hallaq, Hasan Y.; Clarkson, Guy; Thompson, Andrew J.; Silvestr, Linda; Lummis, Sarah C. R.; Lochner, Martin Journal of Medicinal Chemistry, 2010 , vol. 53, # 5 p. 2324 - 2328

76272-41-8 115660-68-9 ~9% 107007-95-4

文献：Bermudez, Jose; Fake, Charles S.; Joiner, Graham F.; Joiner, Karen A.; King, Frank D.; et al. Journal of Medicinal Chemistry, 1990 , vol. 33, # 7 p. 1924 - 1929

上下游产品

上游产品  3
76272-41-8 4498-67-3 115660-68-9
下游产品  0

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%