134395-00-9

• 常用中文名：阿托伐他汀中间体L-2
• 常用英文名：Atorvastatin tert-Butyl Ester
• CAS号：134395-00-9
• 分子式：C₃₇H₄₃FN₂O₅
• 分子量：614.746
• 发布时间：2018-05-26 08:00:00
• 更新时间：2026-06-30 20:23:07

名称

• 中文名: 阿托伐他汀叔丁酯
• 英文名: tert-butyl (3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate
• 中文别名: 阿托伐他汀杂质P; 阿托伐他汀钙中间体L2; 阿托伐他汀杂质O对照品; 阿托伐他汀杂质21; (4R-CIS)-6-[2-[2-(4- 氟苯基 )-5-(1- 异丙基 )-3- 苯基 -4-[( 苯胺 ) 羟基 ]-1H- 吡咯 -1- 基 ] 乙基 ]-2,2- 二甲基 -1,3-二羟基-4; 阿托伐他汀叔丁酯(阿托伐他汀杂质3); 化合物 (3R,5R)-TERT-BUTYL 7-(2-(4-FLUOROPHENYL)-5-ISOPROPYL-3-PHENYL-4-(PHENYLCBAMOYL)-1H-PYRROL-1-YL)-3,5-DIHYDROXYHTANOATE; 阿托伐他汀杂质3(阿托伐他汀叔丁酯); 阿托伐他汀钙杂质15; 阿托伐他汀杂质N; (4R-CIS)-6-[2-[2-(4- 氟苯基 )-5-(1- 异丙基 )-3- 苯基 -4-[( 苯胺 ) 羟基 ]-1H- 吡咯 -1- 基 ] 乙基 ]-2; 阿托伐他汀叔丁基酯; (3R,5R)-7-(2-(4-氟苯基)-5-异丙基-3-苯基-4-(苯基氨甲酰基)-1H-吡咯-1-基)-3,5-二羟基庚酸叔丁酯; 阿托伐他汀钙杂质N; (3R,5R)-7-(2-(4-氟苯基)-5-异丙基-3-苯基-4-(苯基氨甲酰基)-1H-吡咯-1-基)-3,5-二羟基庚酸叔丁酯(阿托伐他汀钙杂质); 阿托伐他汀钙杂质O; 阿伐他汀杂质8; 阿托伐他汀杂质3(阿托伐他汀杂质N); 阿托伐他汀T-丁基酯; 阿托伐他汀杂质N(阿托伐他汀叔丁基酯); 阿托伐他汀3-氟叔丁基酯; (4R-C-S)-6-[-(4-氖苯基)-5-(1-异丙基)-3-苯基-4-[(苤肢)羟基].1H-吡路-1-基1乙基12.2-二甲基-1.3二羟基4-乙酸叔丁酯; 阿托伐他汀钙杂质O对照品
• 英文别名: tert-butyl(3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- (phenylcbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyhtanoate; tert-butyl (3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]-3,5-dihydroxyheptanoate; Atorvastatin 1; tert-Butyl 7-(2-(4-fluorophenyl); Atorvastatin Acid t-Butyl Ester (3R,5R)-7-[3-(Phenylcbamoyl)-5-(4-fluorophenyl)-2isopropyl-4- phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyhtanoic acid t-butyl ester; Atorvastatin impurity 11/Atorvastatin tert-Butyl Ester/(3R,5R)-tert-Butyl 7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyhtanoate; (3R,5R)-tert-Butyl 7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcbamoyl)-1H-pyrrol-1; Atorvastatin Calcium Impurity O Reference Standd; Atorvastatin Calcium Hydrate impurity O; 1H-Pyrrole-1-htanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-Methylethyl)-3-phenyl-4-[(phenylaMino)carbonyl]-, 1,1-diMethylethyl ester, (βR,δR); Atorvastatin 3-Fluoro t-Butyl Ester; 2-Methyl-2-propanyl (3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate; Atorvastatin Impurity 3（Atorvastatin Impurity N）; Atorvastatin tert-Butyl Ester (Atorvastatin Impurity 3); (3R,5R)-7-[2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-phenylcbamoylpyrrol-1-yl]-3,5-dihydroxyhtanoic acid tert-butyl ester; Atorvastatin calcium impurity 15; Atorvastatin Impurity N (Atorvastatin tert-Butyl Ester); Atorvastatin Impurity O reference substance; Atorvastatin Impurity N; Atorvastatin t-butyl ester; Atorvastatin Impurity 21; (R,dR)-2-(4-Fluorophenyl)-,d-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-htanoic Acid 1,1-Dimethylethyl Ester; Atorvastatin Impurity-N (t-Butyl ester); (3R,5R)-tert-Butyl 7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate; Atorvastatin calcium-8; (βR,δR)-Atorvastatin tert-Butyl Ester; (3R,5R)-tert-Butyl 7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyhtanoate (Atorvastatin calcium Impurity); (βR,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-htanoic Acid 1,1-Dimethylethyl Ester; (3R,5R); (|AR,|AR)-2-(4-Fluorophenyl)-|A,|A-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid 1,1-Dimethylethyl Ester; Atorvastatin Acid tert-Butyl Ester; (3R,5R)-tert-Butyl 7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcbamoyl)-1H-pyrrol-1-yl); (4R-cis)-1,1-diMethylethyl-6-[2-[2-(4-fluorophenyl)-5-(1-isopropyl)-3-phenyl-4-[(phenylaMino)carbonyl]-1H-pyrro-1-yl]ethyl]-2,2-diMethyl-1,3-dihydroxy-4-acetate; (βR,δR)-Atorvastatin tert-Butyl Ester (>; 7-[2-(4-Fluoro-phenyl)-5-isopropyl-3-phenyl-4-(phenylcbamoyl)pyrrol-1-yl]-3,5- dihydroxy-htanoic Acid tert-Butyl Ester; ATV imp N ( tertbutyl ester); Atorvastatin Calcium Impurity N; Atorvastatin Impurity 3; (3R,5R)-tert-Butyl 7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcbaMoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyhtanoate; Trimethyl thiazole 13-5; tert-butyl (3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyhtanoate; (3R,5R)-tert-butyl 7-(2-(4-fluorophenyl); Atorvastatin Acid t-Butyl EsterQ: What is Atorvastatin Acid t-Butyl Ester Q: What is the CAS Number of Atorvastatin Acid t-Butyl Ester Q: What is the storage condition of Atorvastatin Acid t-Butyl Ester Q: What e the applications of Atorvastatin Acid t-Butyl Ester; (bR,delt-Atorvastatin tert-Butyl Ester; Atorvastatin Impurity 3 (Atorvastatin tert-Butyl Ester); (R,dR)-2-(4-Fluorophenyl)-,d-dihydroxy-5-(1-Methylethyl)-3-phenyl-4-[(phenylaMino)carbonyl]-1H-pyrrole

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 721.0±60.0 °C at 760 mmHg
• 熔点: 66-68ºC
• 分子式: C₃₇H₄₃FN₂O₅
• 分子量: 614.746
• 闪点: 389.9±32.9 °C
• 精确质量: 614.315613
• PSA: 100.79000
• LogP: 5.95
• 蒸汽压: 0.0±2.4 mmHg at 25°C
• 折射率: 1.574
• 储存条件: -20C

安全

• 危害码 (欧洲): Xi
• 海关编码: 2934999090

合成路线

上下游产品

上游产品  10
125971-95-1 125971-94-0 1035204-85-3 1035204-90-0
459-57-4 125971-86-0 1370478-51-5 442851-51-6
125971-96-2 124401-38-3
下游产品  3
125995-03-1 134523-00-5 134523-01-6

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%