17630-75-0

• 常用中文名：5-氯氧化吲哚
• 常用英文名：5-Chlorooxindole
• CAS号：17630-75-0
• 分子式：C₈H₆ClNO
• 分子量：167.592
• 相关类别： 有机原料 杂环化合物
• 发布时间：2018-09-30 13:06:22
• 更新时间：2024-01-02 17:40:59
• 下载msds

名称

• 中文名: 5-氯氧化吲哚
• 英文名: 5-Chlorooxindole
• 中文别名: 5-氯吲哚-2-酮; 5-氯吲哚酮; 5-氯羟吲哚; 5-氯羟基吲哚; 5-氯吲哚啉-2-酮; 5-氯二氢吲哚-2-酮
• 英文别名: 5-Chlorooxindole; EINECS 412-200-9; 2H-Indol-2-one, 5-chloro-1,3-dihydro-; 5-chloroindolin-2-one; 5-Chloro-1,3-dihydro-2H-indol-2-one; 5-Chloro-2-oxindole; 5-chloro-1,3-dihydroindol-2-one; 5-Chloro-2-indolinone; MFCD00191927

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 348.3±42.0 °C at 760 mmHg
• 熔点: 194-197 °C(lit.)
• 分子式: C₈H₆ClNO
• 分子量: 167.592
• 闪点: 164.5±27.9 °C
• 精确质量: 167.013794
• PSA: 29.10000
• LogP: 2.12
• 外观性状: 灰白色结晶粉末
• 蒸汽压: 0.0±0.8 mmHg at 25°C
• 折射率: 1.602
• 储存条件:

  常温密闭避光，通风干燥

• 稳定性:

  常温常压下稳定

  避免的物料：氧化物
• 分子结构:

  1、 摩尔折射率：42.18

  2、 摩尔体积（m³/mol）：123.0

  3、 等张比容（90.2K）：323.0

  4、 表面张力（dyne/cm）：47.5

  5、 极化率（10^-24cm³）：16.72

• 计算化学:

  1.疏水参数计算参考值（XlogP）:无

  2.氢键供体数量:1

  3.氢键受体数量:1

  4.可旋转化学键数量:0

  5.互变异构体数量:3

  6.拓扑分子极性表面积29.1

  7.重原子数量:11

  8.表面电荷:0

  9.复杂度:183

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

• 更多:

  1. 性状：不确定

  2. 密度（g/mL,25/4℃）：不确定

  3. 相对蒸汽密度（g/mL,空气=1）：不确定

  4. 熔点（ºC）：194 -197 l (it.)

  5. 沸点（ºC,常压）：不确定

  6. 沸点（ºC, 5.2kPa）：不确定

  7. 折射率：不确定

  8. 闪点（ºC）：不确定

  9. 比旋光度（º）：不确定

  10. 自燃点或引燃温度（ºC）：不确定

  11. 蒸气压（kPa,25ºC）：不确定

  12. 饱和蒸气压（kPa,60ºC）：不确定

  13. 燃烧热（KJ/mol）：不确定

  14. 临界温度（ºC）：不确定

  15. 临界压力（KPa）：不确定

  16. 油水（辛醇/水）分配系数的对数值：不确定

  17. 爆炸上限（%,V/V）：不确定

  18. 爆炸下限（%,V/V）：不确定

  19. 溶解性：不确定

MSDS

Name: 5-Chlorooxindole Material Safety Data Sheet Synonym: CAS: 17630-75-0 Section 1 - Chemical Product MSDS Name:5-Chlorooxindole Material Safety Data Sheet Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 17630-75-0 5-Chlorooxindole unlisted Hazard Symbols: XN Risk Phrases: 22 36/37/38 43 62 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Harmful if swallowed. Irritating to eyes, respiratory system and skin. May cause sensitization by skin contact. Possible risk of impaired fertility. Potential Health Effects Eye: Causes eye irritation. Skin: Causes skin irritation. May be harmful if absorbed through the skin. May cause sensitization by skin contact. Ingestion: Harmful if swallowed. May cause irritation of the digestive tract. Inhalation: Causes respiratory tract irritation. May be harmful if inhaled. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 17630-75-0: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Powder Color: off-white Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 194 - 197 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C8H6ClNO Molecular Weight: 167.59 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 17630-75-0 unlisted. LD50/LC50: Not available. Carcinogenicity: 5-Chlorooxindole - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR Not regulated as a hazardous material. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XN Risk Phrases: R 22 Harmful if swallowed. R 36/37/38 Irritating to eyes, respiratory system and skin. R 43 May cause sensitization by skin contact. R 62 Possible risk of impaired fertility. Safety Phrases: S 24 Avoid contact with skin. S 36/37/39 Wear suitable protective clothing, gloves and eye/face protection. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 17630-75-0: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 17630-75-0 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 17630-75-0 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

生态学数据: 对水体是危害的，即使小量产品不能接触地下水，水道或污水系统，未经政府许可勿将材料排入周围环境。

安全

• 符号: GHS07, GHS08
• 信号词: Warning
• 危害声明: H302-H317-H361f-H412
• 警示性声明: P273-P280
• 个人防护装备: Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
• 危害码 (欧洲): Xn:Harmful
• 风险声明 (欧洲): R22;R36/37/38;R43;R62
• 安全声明 (欧洲): S22-S36/37-S61-S45-S36/37/39-S24
• 危险品运输编码: NONH for all modes of transport
• WGK德国: 2
• 海关编码: 2933790090

合成路线

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下游产品  6
100487-33-0 120210-48-2 17630-76-1 113423-48-6
73424-95-0 91098-13-4

海关

海关编码	2933790090
中文概述	2933790090 其他内酰胺. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:9.0% 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%