20977-50-8

• 常用中文名：卡哌隆
• 常用英文名：Carperone
• CAS号：20977-50-8
• 分子式：C₁₉H₂₇FN₂O₃
• 分子量：350.42800
• 发布时间：2018-09-28 18:38:22
• 更新时间：2025-08-26 09:30:20

名称

• 中文名: 卡哌隆
• 英文名: [1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] N-propan-2-ylcarbamate
• 英文别名: CARBAMIC ACID,ISOPROPYL-,1-(3-(p-FLUOROBENZOYL)PROPYL)PIPERID-4-YL ESTER; Carperona [INN-Spanish]; Carperonum; 1-(3-(4-Fluorobenzoyl)propyl)-4-piperidyl N-isopropylcarbamate; Carperonum [INN-Latin]; AL-1021; Carperone; (1-Methylethyl)carbamic acid,1-(4-(4-fluorophenyl)-4-oxobutyl)-4-piperidinyl ester; 1-(4-fluoro-phenyl)-4-(4-isopropylcarbamoyloxy-piperidin-1-yl)-butan-1-one; Carperona

物化性质

• 密度: 1.15g/cm3
• 沸点: 493.7ºC at 760mmHg
• 分子式: C₁₉H₂₇FN₂O₃
• 分子量: 350.42800
• 闪点: 252.4ºC
• 精确质量: 350.20100
• PSA: 62.13000
• LogP: 3.52990
• 蒸汽压: 6.85E-10mmHg at 25°C
• 折射率: 1.533

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : FB3235000 CHEMICAL NAME : Carbamic acid, isopropyl-, 1-(3-(p-fluorobenzoyl)propyl)piperid-4-yl ester CAS REGISTRY NUMBER : 20977-50-8 BEILSTEIN REFERENCE NO. : 1551021 LAST UPDATED : 199612 DATA ITEMS CITED : 6 MOLECULAR FORMULA : C19-H27-F-N2-O3 MOLECULAR WEIGHT : 350.48 WISWESSER LINE NOTATION : T6NTJ A3VR DF& DOVMY1&1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human DOSE/DURATION : 2140 ug/kg TOXIC EFFECTS : Behavioral - rigidity (including catalepsy) Cardiac - change in rate Vascular - BP lowering not characterized in autonomic section REFERENCE : CTCEA9 Current Therapeutic Research, Clinical & Experimental. (Therapeutic Research Press, Inc., POB 514, Tenafly, NJ 07670) V.1- 1959- Volume(issue)/page/year: 11,779,1969 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 310 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,184,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 265 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,184,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 44 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,184,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 25 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,184,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 200 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,184,1972

安全

• 海关编码: 2933399090

海关

海关编码	2933399090
中文概述	2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%