873857-62-6

• 常用中文名：非达霉素
• 常用英文名：fidaxomicin
• CAS号：873857-62-6
• 分子式：C₅₂H₇₄Cl₂O₁₈
• 分子量：1058.039
• 相关类别： 生物化工 抑制剂 DNA损伤(DNA Damage) DNA/RNA Synthesis 抑制剂
• 发布时间：2018-06-12 18:27:16
• 更新时间：2026-06-30 06:13:35
• Fidaxomicin(OPT-80; PAR-101)是选择性的梭状芽孢杆菌抗生素。

名称

• 中文名: 非达霉素
• 英文名: fidaxomicin
• 中文别名: 非达米星,10 MM DMSO 溶液; 化合物:Fidaxomicin; 非达霉素/非达米星; 非达米星; FIDAXOMICIN非达霉素; 罗恩 非达霉素 R021816; (2R,3S,4S,5S,6R)-6-(((3E,5E,8S,9E,11S,12R,13E,15E,18S)-12-(((2R,3S,4R,5S)-二羟基-5-(异丁酰氧基)-6,6-二甲基四氢-2H-吡喃-2-基)氧基)-11-乙基-8-羟基-18-((R)-1-羟乙基)-9,13,15-三甲基-2-氧代环辛二烯-3,5,9,13,15-戊烯-3-基)甲氧基)-4-羟基-5-甲氧基-2-甲基四氢-2H-吡喃-3-基 3,5-二氯-2-乙基-4,6-二羟基苯甲酸酯; 台勾霉素B; 化合物：Fidaxomicin; P-101)是选择性的梭状芽孢杆菌抗生素。; FIDAXOMICIN游离
• 英文别名: lipiarmycin A3; Fidaxomicin R-Tiacumicin B; Not for drug; FidaxoMicinr; FidaxoMicin //BP; P-101; Fidaxomicin; tiacumicin B; Clostomicin B1; 3-(((6-Deoxy-4-O-(3,5-dichloro-2-ethyl-4,6-dihydroxybenzoyl)-2-O-methyl-b-D-mannopyranosyl)oxy)-methyl)-12(R)-[(6-deoxy-5-C-methyl-4-O-(2-methyl-1-oxopropyl)-b-D-lyxo-hexopyranosyl)oxy]-11(S)-ethyl-8(S)-hydroxy-18(S)-(1(R)-hydroxyethyl)-9,13,15-trimethyloxacyclooctadeca-3,5,9,13,15-pentaene-2-one; 3-(((6-Deoxy-4-O-(3,5-dichloro-2-ethyl-4,6-dihydroxybenzoyl)-2-O-methyl-β-D-mannopyranosyl)oxy)-methyl)-12(R)-[(6-deoxy-5-C-methyl-4-O-(2-methyl-1-oxopropyl)-β-D-lyxo-hexopyranosyl)oxy]-11(S)-ethyl-8(S)-hydroxy-18(S)-(1(R)-hydroxyethyl)-9,13,15-trimethyloxacyclooctadeca-3,5,9,13,15-pentaene-2-one; Oxacyclooctadeca-3,5,9,13,15-pentaen-2-one, 3-[[[6-deoxy-4-O-(3,5-dichloro-2-ethyl-4,6-dihydroxybenzoyl)-2-O-methyl-β-D-mannopyranosyl]oxy]methyl]-12-[[6-deoxy-5-C-methyl-4-O-(2-methyl-1-oxopropyl)-β-D-lyxo-hexopyranosyl]oxy]-11-ethyl-8-hydroxy-18-[(1R)-1-hydroxyethyl]-9,13,15-trimethyl-, (3E,5E,8S,9E,11S,12R,13E,15E,18S); clostomicin B1; (2R,3S,4S,5S,6R)-6-(((3E,5E,8S,9E,11S,12R,13E,15E,18S)-12-(((2R,3S,4R,5S)-3,4-Dihydroxy-5-(isobutyryloxy)-6,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-11-ethyl-8-hydroxy-18-((R)-1-hydroxyethyl)-9,13,15-trimethyl-2-oxooxacyclooctadeca-3,5,9,13,15-pentaen-3-yl)methoxy)-4-hydroxy-5-methoxy-2-methyltetrahydro-2H-pyran-3-yl 3,5-dichloro-2-ethyl-4,6-dihydroxybenzoate; Oxacyclooctadeca-3,5,9,13,15-pentaen-2-one, 3-[[[6-deoxy-4-O-(3,5-dichloro-2-ethyl-4,6-dihydroxybenzoyl)-2-O-methyl-β-D-mannopyranosyl]oxy]methyl]-12-[[6-deoxy-5-C-methyl-4-O-(2-methyl-1-oxopropyl)-β-D-lyxo-hexopyranosyl]oxy]-11-ethyl-8-hydroxy-18-[(1R)-1-hydroxyethyl]-9,13,15-trimethyl-, (3E,5E,8S; Fidaxomicin, 10 mM in DMSO; ClostoMicin B1, LipiMycin A3, TiacuMicin B, OPT 80; OPT-80;P-101;CLOSTOMICIN B1;TIACUMICIN B; US-DMF No.; FidaxomicinQ: What is Fidaxomicin Q: What is the CAS Number of Fidaxomicin Q: What is the storage condition of Fidaxomicin Q: What e the applications of Fidaxomicin; 3-(((6-Deoxy-4-O-(3,5-dichloro-2-ethyl-4,6-dihydroxybenzoyl)-2-O-methyl-b-D-mannopyranosyl)oxy)-methyl)-12(R)-[(6-deoxy-5-C-methyl-4-O-(2-methyl-1-oxopropyl)-b-D-lyxo-hexopyranosyl)oxy]-11(S)-eth; Fidaxomycin; Fidaxomicin (OPT-80); fedamycin; (2R,3S,4S,5S,6R)-6-(((3E,5Z,8S,9E,11S,12R,13E,15E,18S)-12-(((2R,3S,4R,5S)-3,4-dihydroxy-5-(isobutyryloxy)-6,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-11-ethyl-8-hydroxy-18-((R)-1-hydroxyethyl)-9,13,15-trimethyl-2-oxooxacyclooctadeca-3,5,9,13,15-pentaen-3-yl)methoxy)-4-hydroxy-5-methoxy-2-methyltetrahydro-2H-pyran-3-yl 3,5-dichloro-2-ethyl-4,6-dihydroxybenzoate; FidaxoMicin(LipiMycin); FidaxoMicin; 3-(((6-Deoxy-4-O-(3,5-dichloro-2-ethyl-4,6-dihydroxybenzoyl)-2-O-methyl-b-D-mannopyranosyl)oxy)-methyl)-12(R)-[(6-deoxy-5-C-methyl-4-O-(2-methyl-1-oxopropyl)-b-D-lyxo-hexopyranosyl)oxy]-11(S)-ethyl-8(S)-hydro; fidaxomicin,Dificid; OPT-80; (2R,3S,4S,5S,6R)-6-({(3E,5E,8S,9E,11S,12R,13E,15E,18S)-12-{[(2R,3S,4R,5S)-3,4-Dihydroxy-5-(isobutyryloxy)-6,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-11-ethyl-8-hydroxy-18-[(1R)-1-hydroxyethyl]-9,13,15-trimethyl-2-oxooxacyclooctadeca-3,5,9,13,15-pentaen-3-yl}methoxy)-4-hydroxy-5-methoxy-2-methyltetrahydro-2H-pyran-3-yl 3,5-dichloro-2-ethyl-4,6-dihydroxybenzoate (non-preferred name); Fentanycin; Lipimycin A3; Dificid; 3-(((6-Deoxy-4-O-(3,5-dichloro-2-ethyl-4,6-dihydroxybenzoyl)-2-O-methyl-β-D-mannopyranosyl)oxy)-methyl)-12(R)-[(6-deoxy-5-C-methyl-4-O-(2-methyl-1-oxopropyl)-β-D-lyxo-hexopyranosyl)oxy]-11(S)-ethyl-8(S)-hydroxy-18(S)-(1(R)-hydroxy; R-Tiacumicin B; Fidaxomicin D7Q: What is Fidaxomicin D7 Q: What is the CAS Number of Fidaxomicin D7 Q: What is the storage condition of Fidaxomicin D7 Q: What e the applications of Fidaxomicin D7; Fidaxomicin Crystalline; Fidaxomicin, >=

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 1046.4±65.0 °C at 760 mmHg
• 分子式: C₅₂H₇₄Cl₂O₁₈
• 分子量: 1058.039
• 闪点: 586.7±34.3 °C
• 精确质量: 1056.425171
• PSA: 266.66000
• LogP: 10.73
• 蒸汽压: 0.0±0.3 mmHg at 25°C
• 折射率: 1.590
• 储存条件: 室温，干燥

生物活性

• 描述: Fidaxomicin(OPT-80; PAR-101)是选择性的梭状芽孢杆菌抗生素。
• 相关类别:
  信号通路 >> 抗感染 >> 细菌
  研究领域 >> 感染
• 参考文献:

  [1]. Fidaxomicin, From Wikipedia