344423-98-9

• 常用中文名：阿托伐他汀钙三水合物
• 常用英文名：atorvastatin calcium trihydrate
• CAS号：344423-98-9
• 分子式：C₆₆H₇₄CaF₂N₄O₁₃
• 分子量：1209.388
• 相关类别： 分析化学 分析试剂 离子色谱试剂
• 发布时间：2018-02-09 08:00:00
• 更新时间：2024-01-04 22:58:53
• Atorvastatin is used primarily for lowering blood cholesterol and for prevention of events associated with cardiovascular disease. Like all statins, atorvastatin works by inhibiting HMG-CoA reductase, an enzyme found in liver tissue that plays a key role in production of cholesterol in the body.Atorvastatin is also used for the treatment of dyslipidemia.

名称

• 中文名: 阿托伐他汀钙三水合物
• 英文名: atorvastatin calcium trihydrate
• 中文别名: 阿托伐他汀钙水合物
• 英文别名: atorvastatin calcium trihydrate; 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, calcium salt, (βR,δR)-, hydrate (2:1:3); Torvast; Atorvastatin Calcium Salt Trihydrate; Atorvastatin hemicalcium salt sesquihydrate; Lipitor; 1H-Pyrrole-1-heptanoicacid, 2-(4-fluorophenyl)-b,d-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-,calcium salt, hydrate (2:1:3), (bR,dR)-; Calcium (3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate hydrate (1:2:3); Sortis; Totalip

物化性质

• 分子式: C₆₆H₇₄CaF₂N₄O₁₃
• 分子量: 1209.388
• 精确质量: 1208.484619
• PSA: 256.93000
• LogP: 9.91090
• 外观性状: 固体;White to Almost white powder to crystal
• 储存条件: 室温，干燥
• 水溶解性: Very slightly soluble in water, slightly soluble in ethanol (96 per cent), practically insoluble in methylene chloride.

安全

• 符号: GHS07, GHS08
• 信号词: Danger
• 危害声明: H319-H360D
• 警示性声明: P201-P280-P305 + P351 + P338-P308 + P313-P337 + P313
• 危害码 (欧洲): T
• 风险声明 (欧洲): 61-36
• 安全声明 (欧洲): 53-26-45
• 危险品运输编码: NONH for all modes of transport