74849-93-7

• 常用中文名：Cefpiramide sodium
• 常用英文名：Cefpiramide sodium
• CAS号：74849-93-7
• 分子式：C₂₅H₂₃N₈NaO₇S₂
• 分子量：634.6
• 相关类别： 原料药 抗生素类药物 头孢菌素类药
• 发布时间：2018-09-09 17:03:59
• 更新时间：2026-07-01 16:18:33
• Cefpiramide钠盐(Wy-44635; SM-1652)是一种新的假单胞菌活性的广谱头孢菌素与抗菌活性。

名称

• 中文名: 头孢匹胺钠
• 英文名: cefpiramide sodium
• 中文别名: 头孢匹胺钠科研试剂; 甲吡唑头孢菌素钠; (6R,7R)-7-[[(2R)-2-(4-羟基苯基)-2-[(6-甲基-4-氧代-1H-吡啶-3-甲酰)氨基]乙酰]氨基]-3-[(1-甲基四唑-5-基)硫甲基]-8-氧代-5-硫杂-1-氮杂双环[4.2.0]辛-2-烯-2-甲酸钠; 头孢吡胺钠; Cefpiramide sodium :头孢匹胺钠
• 英文别名: 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-cboxylic acid, 7-[[(2R)-[[(4-hydroxy-6-methyl-3-pyridinyl)carbonyl]amino](4-hydroxyphenyl)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, monosodium salt, (6R,7R); 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-cboxylic acid, 7-[[[[(4-hydroxy-6-methyl-3-pyridinyl)carbonyl]amino](4-hydroxyphenyl)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, monosodium salt, [6R-[6α,7β(R*)]]; Sodium (6R,7R)-7-[[(2R)-2-(4-hydroxyphenyl)-2-[(6-methyl-4-oxo-1H-pyridine-3-carbonyl)amino]acetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; SM-1652;WY-44635; 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2R)-[[(4-hydroxy-6-methyl-3-pyridinyl)carbonyl]amino](4-hydroxyphenyl)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,monosodium salt,(6R,7R); Sepatren; SM 1652; Cefpiran; Cefpiramide sodium //BP; Cefpiramide Sodium L; Antibiotic SM; Sodium (6R,7R)-7-[[(2R)-2-(4-hydroxyphenyl)-2-[(6-methyl-4-oxo-1H-pyridine-3-carbonyl)amino]acetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-cboxylate; Suncefal; Cefpiamine sodium; TIANFU CHEM-Cefpiramide sodiumethane complex; Satren; Cefpriamide free acid; Antibiotic SM 1652; Cefpiamide sodium

物化性质

• 分子式: C₂₅H₂₃N₈NaO₇S₂
• 分子量: 634.6
• 精确质量: 634.10288173
• PSA: 266.19000
• 外观性状: 白色至略淡黄色结晶粉末
• 储存条件: -20℃

生物活性

• 描述: Cefpiramide钠盐(Wy-44635; SM-1652)是一种新的假单胞菌活性的广谱头孢菌素与抗菌活性。
• 相关类别:
  信号通路 >> 抗感染 >> 细菌
  研究领域 >> 感染
• 参考文献:

  [1]. Barry AL, et al. Cefpiramide: comparative in-vitro activity and beta-lactamase stability. J Antimicrob Chemother. 1985 Sep;16(3):315-25.

  [2]. Fu KP, et al. Therapeutic efficacy of cefpiramide and cefoperazone alone and in combination with gentamicin against pseudomonal infections in neutropenic mice. Chemotherapy. 1986;32(2):166-72.

  [3]. Neu HC, et al. The in vitro activity and beta-lactamase stability of cefpiramide compared with other beta-lactam antibiotics. Diagn Microbiol Infect Dis. 1985 Nov;3(6):479-88.