332-51-4

• 常用中文名：2-[(4-氟苯基)硫代]乙酸
• 常用英文名：(4-fluorophenylthio)acetic acid
• CAS号：332-51-4
• 分子式：C₈H₇FO₂S
• 分子量：186.20300
• 发布时间：2018-05-27 08:00:00
• 更新时间：2024-01-07 18:19:35
• 下载msds

名称

• 中文名: (4-氟苯基硫)乙酸
• 英文名: 2-(4-fluorophenyl)sulfanylacetic acid
• 中文别名: 2-[(4-氟苯基）硫代]乙酸; (4-氟苯硫基)乙酸
• 英文别名: 2-[(4-fluorophenyl)thio]acetic acid; (4-fluoro-phenylsulfanyl)-acetic acid; F0917-0657; (4-Fluor-phenylmercapto)-essigsaeure; MFCD00219825; (4-Fluorophenylthio)Acetic Acid; (p-fluorophenylthio)acetic acid; p-FC6H4SCH2COOH

物化性质

• 密度: 1.36 g/cm3
• 沸点: 315.4ºC at 760 mmHg
• 熔点: 76-79°C
• 分子式: C₈H₇FO₂S
• 分子量: 186.20300
• 闪点: 144.5ºC
• 精确质量: 186.01500
• PSA: 62.60000
• LogP: 2.00240
• 外观性状: 灰白色至白色结晶固体
• 储存条件: 2-8°C
• 分子结构:

  1、 摩尔折射率：45.78

  2、 摩尔体积（m³/mol）：136.5

  3、 等张比容（90.2K）：365.6

  4、 表面张力（dyne/cm）：51.4

  5、 极化率（10 ^-24cm ³）：18.15

• 更多:

  一、物性数据

  性状：不可用

  密度（g/mL,25/4℃）：不可用

  相对蒸汽密度（g/mL,空气=1）：不可用

  熔点（ºC）：76-79

  沸点（ºC,常压）：不可用

  沸点（ºC,5.2kPa）：不可用

  折射率：不可用

  闪点（ºC）：不可用

  比旋光度（º）：不可用

  自燃点或引燃温度（ºC）：不可用

  蒸气压（kPa,25ºC）：不可用

  饱和蒸气压（kPa,60ºC）：不可用

  燃烧热（KJ/mol）：不可用

  临界温度（ºC）：不可用

  临界压力（KPa）：不可用

  油水（辛醇/水）分配系数的对数值：不可用

  爆炸上限（%,V/V）：不可用

  爆炸下限（%,V/V）：不可用

  溶解性：不可用

MSDS

Name: 2-[(4-Fluorophenyl)thio]acetic acid 97% Material Safety Data Sheet Synonym: CAS: 332-51-4 Section 1 - Chemical Product MSDS Name:2-[(4-Fluorophenyl)thio]acetic acid 97% Material Safety Data Sheet Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 332-51-4 2-[(4-Fluorophenyl)thio]acetic acid 97% unlisted Hazard Symbols: XI Risk Phrases: 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Irritating to eyes, respiratory system and skin. Potential Health Effects Eye: Causes eye irritation. Skin: Causes skin irritation. May be harmful if absorbed through the skin. Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed. Inhalation: Causes respiratory tract irritation. May be harmful if inhaled. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 332-51-4: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: white crystalline solid Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 76 - 69 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C8H7FO2S Molecular Weight: 186 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Strong oxidizing agents, bases, reducing agents. Hazardous Decomposition Products: Carbon monoxide, oxides of sulfur, carbon dioxide, fluorine, hydrogen fluoride gas. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 332-51-4 unlisted. LD50/LC50: Not available. Carcinogenicity: 2-[(4-Fluorophenyl)thio]acetic acid - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA No information available. IMO No information available. RID/ADR No information available. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XI Risk Phrases: R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 Wear suitable gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 332-51-4: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 332-51-4 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 332-51-4 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

毒理学数据: 二、毒理学数据： 急性毒性：不可用。 生态学数据: 三、生态学数据： 1、其它有害作用：该物质对环境可能有危害，对水体应给予特别注意。

安全

• 危害码 (欧洲): Xi:Irritant;
• 风险声明 (欧洲): R36/37/38
• 安全声明 (欧洲): S26-S36/37/39
• 海关编码: 2930909090

合成路线

226396-70-9 ~97% 332-51-4

文献：Zhang, Yue-Mei; Fan, Xiaodong; Yang, Shyh-Ming; Scannevin, Robert H.; Burke, Sharon L.; Rhodes, Kenneth J.; Jackson, Paul F. Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 1 p. 405 - 408

371-42-6 79-11-8 ~53% 332-51-4

文献：Protiva, Miroslav; Jilek, Jiri; Rajsner, Miroslav; Sindelar, Karel; Bartl, Vaclav; et al. Collection of Czechoslovak Chemical Communications, 1987 , vol. 52, # 7 p. 1811 - 1833

140-89-6 ~% 332-51-4

文献：US2061200 , ; US2061186 , ;

371-40-4 ~% 332-51-4

文献：Organic Preparations and Procedures International, , vol. 30, # 3 p. 349 - 352

68-11-1 96783-59-4 ~% 332-51-4

文献：Organic Preparations and Procedures International, , vol. 30, # 3 p. 349 - 352

79-11-8 371-40-4 ~% 332-51-4

文献：J. Gen. Chem. USSR (Engl. Transl.), , vol. 32, # 6 p. 1870 - 1874,1849 - 1852

上下游产品

上游产品  5
371-42-6 79-11-8 140-89-6 371-40-4
68-11-1
下游产品  5
371-15-3 371-42-6 298-12-4 383-38-0
405-31-2

海关

海关编码	2930909090
中文概述	2930909090. 其他有机硫化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%