280755-12-6

• 常用中文名：土拉霉素 B
• 常用英文名：Tulathromycin B
• CAS号：280755-12-6
• 分子式：C₄₁H₇₉N₃O₁₂
• 分子量：806.079
• 相关类别： 信号通路 抗感染 细菌
• 发布时间：2018-03-27 08:00:00
• 更新时间：2024-04-06 10:14:35
• Tulathromycin B (CP 547272) 是 Tulathromycin (一种大环内酯类抗生素) 的异构体

名称

• 中文名: 托拉菌素 B
• 英文名: Tulathromycin B
• 中文别名: 土拉霉素 B; 托拉菌素
• 英文别名: 1-Oxa-4-azacyclotridecan-13-one, 11-[[2,6-dideoxy-3-C-methyl-3-O-methyl-4-C-[(propylamino)methyl]-α-L-ribo-hexopyranosyl]oxy]-2-[(1R,2R)-1,2-dihydroxy-1-methylbutyl]-8-hydroxy-3,6,8,10,12-pentamet hyl-9-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (2R,3R,6R,8R,9R,10S,11S,12R)-; (2R,3R,6R,8R,9R,10S,11S,12R)-2-[(2R,3R)-2,3-Dihydroxy-2-pentanyl]-8-hydroxy-3,6,8,10,12-pentamethyl-13-oxo-9-{[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy}-1-oxa-4-azacyclotridecan- 11-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-4-C-[(propylamino)methyl]-α-L-ribo-hexopyranoside; Tulathromycin; Draxxin; (2R,3R,6R,8R,9R,10S,11S,12R)-11-[[2,6-Dideoxy-3-C-methyl-3-O-methyl-4-C-[(propylamino)methyl]-a-L-ribo-hexopyranosyl]oxy]-2-[(1R,2R)-1,2-dihydroxy-1-methylbutyl]-8-hydroxy-3,6,8,10,12-pentamethyl-9-[[3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl]oxy]-1-oxa-4-azacyclotridecan-13-one

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 870.5±65.0 °C at 760 mmHg
• 分子式: C₄₁H₇₉N₃O₁₂
• 分子量: 806.079
• 闪点: 480.3±34.3 °C
• 精确质量: 805.566345
• PSA: 200.90000
• LogP: 3.17
• 蒸汽压: 0.0±0.6 mmHg at 25°C
• 折射率: 1.536
• 储存条件: 2-8°C

生物活性

• 描述: Tulathromycin B (CP 547272) 是 Tulathromycin (一种大环内酯类抗生素) 的异构体
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 细菌
• 参考文献:

  [1]. Ana BERGANT SIMONCIC, et al. Process for preparation of tulathromycin. Patent. WO2015014907.