144163-85-9

• 常用中文名：[(1S,3S,4S)-4-氨基-3-羟基-5-苯基-1-(苯甲基)戊基]氨基甲酸叔丁酯
• 常用英文名：[(1S,3S,4S)-4-Amino-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]carbamic acid 1,1-dimethylethyl ester
• CAS号：144163-85-9
• 分子式：C₂₃H₃₂N₂O₃
• 分子量：384.512
• 发布时间：2018-10-15 17:37:19
• 更新时间：2026-08-02 05:57:23

名称

• 中文名: [(1S,3S,4S)-4-氨基-3-羟基-5-苯基-1-(苯甲基)戊基]-氨基甲酸叔丁酯
• 英文名: tert-Butyl ((2S,4S,5S)-5-amino-4-hydroxy-1,6-diphenylhexan-2-yl)carbamate
• 中文别名: 利托那韦中间体BDC; [(1S,3S,4S)-4-氨基-3-羟基-5-苯基-1-(苯甲基)戊基]-氨基甲酸叔丁; [(2S,3S,5S)-5-(叔丁氧羰基)氨基-2-氨基-3-羟基-1,6-二羟基己烷(BDH ); 氨基甲酸叔丁酯((2S,4S,5S)-5-氨基-4-羟基-1,6-二苯基己-2-基); (2S,3S,5S)-2-氨基-3-羟基-5-叔丁氧基甲酰氨基-1,6-二苯基己烷; (2S,3S,5S)-5-(叔丁氧羰基)氨基-2-氨基-3-羟基-1,6-二苯基己烷(BDH ); 利托那韦中间体BDH; (2S,3S,5S)-5-叔丁氧基甲酰氨基-2-氨基-3-羟基-1,6-二苯基己烷; 叔丁基((2S,4S,5S)-5-氨基-4-羟基-1,6-二苯基己烷-2-基)氨基甲酸酯; 利托那韦中间体8; [(2S,3S,5S)-5-(叔丁氧羰基)氨基-2-氨基-3-羟基--1,6-二羟基己烷(BDH PURE); ((2S,4S,5S)-5-氨基-4-羟基-1,6-二苯基己-2-基)氨基甲酸叔丁酯; (2S,3S,5S)-5-叔丁氧基甲酰氨基-2-氨基-3-羟基-1,6-二苯基己烷(BDH ); [(1S,3S,4S)-4-氨基-3-羟基-5-苯基-1-(苯甲基)戊基]-氨基甲酸叔丁酯(BDH); 利托那韦中间8; (2S,3S,5S)-5-叔丁羰基氨基-2-氨基-3-羟基-1, 6-二苯基己烷; (2S,3S,5S)-5-(叔丁氧羰基)氨基-2-氨基-3-羟基-1,6-二苯基己烷(BDH)
• 英文别名: (2S,3S,5S)-5-(Tert-Butyloxycabonyll)amino-2-amino-3-Hydroxy-1,6-Diphenyhexane; (2S,3S,5S)-2-amino-3-hydroxy-5-(t-butyloxycbonylaMino)-1,6-diphenylhexane; (2S,3S,5S)-2-Amino-3-hydroxy-5-(tert-butyloxycarbonylamino)-1,6-diphenylhexane; BDH of ritonavir intermediate; (2S,3S,5S)-2-amino-3-hydroxy-5-(t-butyloxycbonylamino-1,6-diphenyl-hexane succinic acid; [(1S,3S,4S)-4-Amino-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-cbamic acid 1,1-dimethylethyl ester in stock GMP Factory; [(1S,3S,4S)-4-Amino-3-hydroxy-5-phenyl-1-(phenylMethyl)pentyl]-cbaMic acid 1,1-diMethylethyl ester (Ritonavir); [2S,3S,5S]-2-Amino-3-hydroxy-5-(t-butyl carbonyl amino)-1,6- diphenyl hexane; [(1s,3s,4s)-4-amino-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-cbamic acid 1,1-dimethylethyl ester; (2S,3S,5S)-2-amino-3-hydroxy-5-(t-butyloxycbonylaMino-1,6-diphenyl-hexane succinic; 2-Methyl-2-propanyl [(2S,4S,5S)-5-amino-4-hydroxy-1,6-diphenyl-2-hexanyl]carbamate; Cbamic acid,[(1s,2s,4s)-4-amino-3-Hydroxy-5-phenyl-1-pheny; (2S,3S,5S)-2-amino-3-hydroxy-5-(t-butyloxycbonylamino; Carbamic acid, N-[(1S,3S,4S)-4-amino-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-, 1,1-dimethylethyl ester; 2S,3S,5S)-5-t-Butyloxycbonylamino-2-amino-3-hydroxy-1,6-diphenylhexane (BDH ); (2S,3S,5S)-5-(Tert-butoxybonyl)amino-2-amino-3hydroxy-1,6-diphenyl hexane; (2S,3S,5S)-5-(Tert-Butyloxycabonyll)amino-2-amino-3-Hydroxy-1,6-Dipheny; [(1S,3S,4S)-4-Amino-3-hydroxy-5-phenyl-1-(phenylMethyl)pentyl]cbaMic acid; N-[(1S,3S,4S)-1-Benzyl-3-hydroxy-5-phenyl-4-aMinopentyl]cbaMic Acid tert-Butyl Ester; N-[(1S,3S,4S)-4-Amino-3-hydroxy-5-phenyl-1-(phenylMethyl)pentyl]cbaMic Acid 1,1-DiMethylethyl Ester; (2S,3S,5S)-5-tert-ButyloxycbonylaMino-2-amino-3-hydroxy -1,6-diphenylhexane; [(1s,2s,4s)-4-amino-3-Hydroxy-5-phenyl-1-phenylmethyl]pentyl-1,1-dimethylethyl ester); (2S,3S,5S)-2-Amino-3-Hydroxy-5(T)-Butyloxycbonylamino-1,6-Diphenyl-HexaneSuccinicAcid; (2S,3S,5S)-2-Amino-3-Hydroxy-5-(Tert-Butyloxycbonylamino)-1,6-Diphenyl Hexane Succinic Acid; tert-butyl N-[(2S,4S,5S)-5-amino-4-hydroxy-1,6-diphenylhexan-2-yl]cbaMate; Cbamic acid, N-[(1S,3S,4S)-4-amino-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-, 1,1-dimethylethyl ester; ert-Butyl((2S,4S,5S)-5-amino-4-hydroxy-1,6-diphenylhexan-2-yl)cbamate; tert-Butyl N-[(1S,3S,4S)-4-amino-3-hydroxy-5-phenyl-1-(benzyl)pentyl]cbamate; (2S,3S,5S)-5-(Tert-butoxybonyl)amino-2-amino-3-hydroxy-1,6-diphenyl hexane; (2S, 3S, 5S) -5- (tert-butoxycbonyl) amino-2-amino-3-hydroxy-1,6-diphenylhexane; [(1S,3S,4S)-4-Amino-3-hydroxy-5-phenyl-1-(phenyl-methyl)pentyl]cbamic acid 1,1-dimethyl ethyl e; 1,1-Dimethylethyl N-[(1S,3S,4S)-4-amino-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]cbamate; (2S,4S,5S)-5-Amino-2-(Boc-amino)-4-hydroxy-1,6-diphenylhexane; [(1S,3S,4S)-4-Amino-3-hydroxy-5-phenyl-1-(phenyl-methyl)pentyl]cbamic acid 1,1-dimethyl ethy; BDH salt; [(1S,3S,4S)-4-Amino-3-Hydroxy; tert-Butyl ((2S,4S,5S)-5-amino-4-hydroxy-1,6-diphenylhexan-2-yl)cbaMate; Cbamic acid,[(1s,2s,4s)-4-amino-3-Hydroxy-5-phenyl-1-phenylmethyl]pentyl-1,1-dimethylethyl ester; ((2S,4S,5S)-5-amino-4-hydroxy-1,6-diphenylhexan-2-yl)cbamate; (2S,3S,5S)-5-(Tert-butyloxycbonyl)amino-2-amino-3-hydroxy-1,6-diphenyl hexane (BDH ); tert-Butyl [(2S,4S,5S)-5-amino-4-hydroxy-1,6-diphenylhexan-2-yl]carbamate

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 569.2±50.0 °C at 760 mmHg
• 熔点: 71-74°C
• 分子式: C₂₃H₃₂N₂O₃
• 分子量: 384.512
• 闪点: 298.0±30.1 °C
• 精确质量: 384.241302
• PSA: 84.58000
• LogP: 4.46
• 蒸汽压: 0.0±1.6 mmHg at 25°C
• 折射率: 1.562
• 储存条件: 2-8°C

安全

• 危害码 (欧洲): Xi

合成路线

256328-84-4 ~% 144163-85-9

文献：US2005/131017 A1, ; Page/Page column 98; 99 ;

162849-93-6 ~% 144163-85-9

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 21 p. 3101 - 3103

24424-99-5 ~% 144163-85-9

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 21 p. 3101 - 3103

156732-15-9 ~% 144163-85-9

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 21 p. 3101 - 3103

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