40675-45-4

• 常用中文名：1-benzyl-4-nitrosopiperazine
• 常用英文名：1-benzyl-4-nitrosopiperazine
• CAS号：40675-45-4
• 分子式：C₁₁H₁₅N₃O
• 分子量：205.25600
• 发布时间：2016-02-04 06:31:51
• 更新时间：2024-01-11 12:19:25

名称

• 英文名: 1-benzyl-4-nitrosopiperazine
• 英文别名: 1-nitroso-4-benzylpiperazine; 4-Benzyl-1-nitroso-piperazin; N-nitroso-N-benzylpiperazine; 1-benzyl-4-nitroso-4-piperizine; 1-benzyl-4-nitroso-piperazine; Piperazine,1-benzyl-4-nitroso; 4-nitroso-1-benzylpiperazine; N1-Benzyl-N4-nitroso-piperazin; 1-Benzyl-4-nitroso-piperazin

物化性质

• 密度: 1.16g/cm3
• 沸点: 350.6ºC at 760mmHg
• 熔点: 56-58ºC
• 分子式: C₁₁H₁₅N₃O
• 分子量: 205.25600
• 闪点: 165.8ºC
• 精确质量: 205.12200
• PSA: 35.91000
• LogP: 1.36140
• 折射率: 1.595

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TK8379000 CHEMICAL NAME : Piperazine, 1-benzyl-4-nitroso- CAS REGISTRY NUMBER : 40675-45-4 BEILSTEIN REFERENCE NO. : 0172918 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C11-H15-N3-O HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 125 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 2,280,1968

安全

• 海关编码: 2933599090

合成路线

2759-28-6 ~34% 40675-45-4

文献：KARYOPHARM THERAPEUTICS, INC.; SANDANAYAKA, Vincent, P.; SHACHAM, Sharon; MCCAULEY, Dilara; SHECHTER, Sharon Patent: WO2013/19548 A1, 2013 ; Location in patent: Page/Page column 73 ; WO 2013/019548 A1

5632-47-3 100-39-0 ~% 40675-45-4

文献：Manetti, Dina; Mannelli, Lorenzo Di Cesare; Dei, Silvia; Galeotti, Nicoletta; Ghelardini, Carla; Romanelli, Maria Novella; Scapecchi, Serena; Teodori, Elisabetta; Pacini, Alessandra; Bartolini, Alessandro; Gualtieri, Fulvio Journal of Medicinal Chemistry, 2005 , vol. 48, # 20 p. 6491 - 6503

100-39-0 ~% 40675-45-4

文献：Zhang, Yinsheng; Stolle, Wayne T. Journal of Labelled Compounds and Radiopharmaceuticals, 2010 , vol. 53, # 5-6 p. 487 - 489

上下游产品

上游产品  3
2759-28-6 5632-47-3 100-39-0
下游产品  1
39139-52-1

海关

海关编码	2933599090
中文概述	2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%