13118-11-1

• 常用中文名：N--3-吡咯烷基环戊基扁桃酸酯(非对映异构体的混合物)
• 常用英文名：N-Methyl-3-pyrrolidinyl Cyclopentylmandelate
• CAS号：13118-11-1
• 分子式：C₁₈H₂₅NO₃
• 分子量：303.39600
• 发布时间：2018-12-17 18:26:38
• 更新时间：2026-07-11 12:44:44

名称

• 中文名: N-甲基-3-吡咯烷基 环戊基扁桃酸酯
• 英文名: (1-methylpyrrolidin-3-yl) 2-cyclopentyl-2-hydroxy-2-phenylacetate
• 中文别名: 格隆溴铵杂质30; 1-甲基吡咯烷-3-基2-环戊基-2-羟基-2-苯乙酸酯; 溴化吡咯烷酮杂质G; 2-环戊基-2-羟基-2-苯基乙酸(1-甲基-3-羟基)吡咯烷酯; 溴化格隆铵杂质G(格隆溴铵相关化合物B); 2-环戊基-扁桃酸N-甲基-吡咯烷-3-醇酯; 格隆溴铵相关化合物B; 格隆溴胺杂质B(N-甲基-3-吡咯烷基 环戊基扁桃酸酯); 格隆溴铵中间体; N-3-吡咯烷基环戊基扁桃酸酯(非对映异构体的混合物); 格隆溴铵中间体B; 2-环戊基羟基苯基乙酸(1'-甲基-3'羟基)吡咯烷酯; N-3-吡咯烷基环戊基扁桃酸酯; 格隆溴铵中间体D; 格隆溴铵 杂质 G(格隆溴铵 相关化合物 B); 格隆溴铵杂质B; 1-甲基吡咯烷-3-基 2-环戊基-2-羟基-2-苯基乙酸酯; 甘罗溴铵相关化合物B; 格隆溴铵杂质G; 格隆溴铵杂质02; 甘罗溴铵相关物质B; 甘罗溴铵杂质B
• 英文别名: GlycopyrroniuM BroMide interMediate B; Glycopyrrolate Related Compound B (75 mg) (1-Methylpyrrolidin-3-yl 2-cyclopentyl-2-hydroxy-2-phenylacetate); a-Cyclopentyl-mandelic Acid 1-Methyl-3-pyrrolidinyl Ester; Glonium bromide impurity G; Glycopyrrolate Impurity 30; N-Methyl-3-pyrrolidinyl Cyclopentylmandelate (Glycopyrrolate Impurity G); N-methyl-3-pyrrolidylcyclopentyl mandelic acid ester; 1-Methyl-3-pyrrolidinyl α-cyclopentyl-α-hydroxybenzeneacetate; Benzeneacetic acid, α-cyclopentyl-α-hydroxy-, 1-methyl-3-pyrrolidinyl ester; Glycopyrrolate Impurity G; Glycopurrolate Related Compound B; Glycopyrrolate Related Compound B; α-Cyclopentyl-α-hydroxy-benzeneacetic Acid 1-Methyl-3-pyrrolidinyl Ester; Glycopyrrolate Related; Glycopurrolate RC B; α-Cyclopentyl-α-hydroxybenzeneacetic acid 1-methylpyrrolidin-3-yl ester; N-Methyl-3-pyrrolidinyl CyclopentylMandelate (Mixture of diastereoMers); EINECS 236-047-0; 3-[(cyclopentyl-hydroxyphenylacetyl)oxy]-1-methylpyrrolidine; 1-methyl-3-pyrrolidinyl cyclopentylmandelate; a-Cyclopentyl-a-hydroxy-benzeneacetic Acid 1-Methyl-3-pyrrolidinyl Ester; (1-methylpyrrolidin-3-yl) 2-cyclopentyl-2-hydroxy-2-phenylacetate 13-1 -- 1 gm; Cyclopentyl-phenylglykolsaeure-1-methyl-3-pyrrolidinylester; 1-Methylpyrrolidin-3-yl 2-cyclopentyl-2-hydroxy-2-phenylacetate; 11H-Dibenzo[b,e][1,4]diazin-11-one,5,11-dihydro; Glycopyrrolate Impurity B; Glycopyrrolate RC B; Glycopyrrolate Related Compound B (1-Methylpyrrolidin-3-yl 2-cyclopentyl-2-hydroxy-2-phenylacetate); 2-Cyclopentyl-mandelic Acid N-Methyl-pyrrolidin-3-ol Ester; cyclopentyl-hydroxy-phenyl-acetic acid 1-methyl-pyrrolidin-3-yl ester; 1-Methylpyrrolidin-3-yl -2-cyclopentylhydroxyphenylacetate; Glycopyrronium Bromide Impurity G; Gluon Bromide Impurity G; α-Cyclopentyl-mandelic Acid 1-Methyl-3-pyrrolidinyl Ester; Benzeneacetic acid, a-cyclopentyl-a-hydroxy-,1-Methyl-3-pyrrolidinyl ester; 1-methylpyrrolidin-3-yl cyclopentylphenylglycolate; Glycopyrronium Bromide Impurity G (Glycopyrrolate Related Compound B)

物化性质

• 密度: 1.17g/cm3
• 沸点: 434.6ºC at 760mmHg
• 分子式: C₁₈H₂₅NO₃
• 分子量: 303.39600
• 闪点: 216.7ºC
• 精确质量: 303.18300
• PSA: 49.77000
• LogP: 2.24960
• 外观性状: 粘稠油状或半固体
• 储存条件: 2-8°C

安全

• 符号: GHS07
• 信号词: Warning
• 危害声明: H302
• 警示性声明: P301 + P312 + P330
• 危害码 (欧洲): Xn
• 危险品运输编码: NONH for all modes of transport
• 海关编码: 2933990090

合成路线

13220-33-2 19833-96-6 ~70% 13118-11-1

文献：Bodor, Nicholas S. Patent: US2007/123557 A1, 2007 ; Location in patent: Page/Page column 9 ; US 20070123557 A1

13220-33-2 427-49-6 ~% 13118-11-1

文献：WO2010/115937 A1, ; Page/Page column 13; 16-17 ;

15206-55-0 ~% 13118-11-1

文献：Organic Process Research and Development, , vol. 16, # 11 p. 1754 - 1769

19833-96-6 ~% 13118-11-1

文献：Organic Process Research and Development, , vol. 16, # 11 p. 1754 - 1769

15206-55-0 ~% 13118-11-1 1404453-84-4

文献：Organic Process Research and Development, , vol. 16, # 11 p. 1754 - 1769

19833-96-6 ~% 13118-11-1 1404453-84-4

文献：Organic Process Research and Development, , vol. 16, # 11 p. 1754 - 1769

13220-33-2 427-49-6 530-62-1 ~% 13118-11-1 详细

文献：Organic Process Research and Development, , vol. 16, # 11 p. 1754 - 1769

上下游产品

上游产品  5
13220-33-2 19833-96-6 427-49-6 15206-55-0
530-62-1
下游产品  1
65976-16-1

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%