52486-19-8

52486-19-8结构式

常用中文名：1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione
常用英文名：1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione
CAS号：52486-19-8
分子式：C₁₀H₁₄N₂O₆
分子量：258.23
相关类别：信号通路细胞周期/DNA损伤核苷抗代谢药/类似物
发布时间：2017-06-18 01:39:49
更新时间：2026-07-12 13:18:29
1-(β-D-呋喃甲酰基)-5-甲基尿嘧啶是胸苷类似物。该系列的类似物对复制的DNA具有插入活性。它们可以用于标记细胞和跟踪DNA合成[1]。

英文名	1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
英文别名	1-(-D-Xylofuranosyl)-5-methyluracil 1-(beta-D-Xylofuranosyl)-5-methyluracil 9-(bbeta-D-Xylofuranosyl)-5-methyluracil, xylo-5-methyl uridine 5-Methyl-1-β-D-xylofuranosyl-2,4(1H,3H)-pyrimidinedione Xylo-5-methyluridine 9-(b-D-Xylofuranosyl)-5-methyluracil, xylo-5-methyl uridine 1-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione 1-(b-D-Xylofuranosyl)-5-methyluracil 2,4(1H,3H)-Pyrimidinedione, 5-methyl-1-β-D-xylofuranosyl

描述	1-(β-D-呋喃甲酰基)-5-甲基尿嘧啶是胸苷类似物。该系列的类似物对复制的DNA具有插入活性。它们可以用于标记细胞和跟踪DNA合成[1]。
相关类别	研究领域 >> 癌症信号通路 >> 细胞周期/DNA损伤 >> 核苷抗代谢药/类似物
参考文献	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. [2]. Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93.