61848-66-6

• 常用中文名：二氯-1R,2R-1,2-环己二胺合铂
• 常用英文名：trans(−)-DDCP
• CAS号：61848-66-6
• 分子式：C₆H₁₄Cl₂N₂Pt
• 分子量：380.18
• 发布时间：2017-05-21 00:36:00
• 更新时间：2026-09-21 17:07:38

名称

• 中文名: (1,3-二氨基环己烷)二氯化铂
• 英文名: Platinum, dichloro(1,2-cyclohexanediamine-N,N')-, [SP-4-2-(1R-trans)]
• 中文别名: 奥沙利铂(系统使用性用); 顺式- 二氯((1R,2R)-(-)-1,2-环己二胺)合铂; SP-4-2-(1R反式)]-(1,2-环己烷二胺-N,N')二氯铂(II); 奥沙利铂系统适应; 顺式-二氯-反式-1,2-环己二胺合铂; 奥沙利铂 标准品; 二氯二铵环己烷铂; [SP-4-2-(1R-反式)]-(1,2-环己烷二胺-N,N')二氯化物铂Ⅱ; 顺式-二氯-反式-1,2-环己二胺合铂(奥沙利铂中间体); SP-4-2-(1R-反式)]-(1,2-环己烷二胺-N,N')二氯化物铂(II); (1R,2R)-1,2-环己二胺]二氯化铂
• 英文别名: Dichlorodiammonium cyclohexane platinum; Oxaliplatin System Suitability (25 mg) ([SP-4-2-(1R-trans)]-(1,2-cyclohexanediamine-N,N') dichloridoplatinum(II)); Platinum, dichloro(1,2-cyclohexanediamine-N,N')-, (sp-4-2-(1R-trans)); Dichloro(1R,2R-cyclohexanediammine)platinum(II); Oxaliplatin System Suitability ([SP-4-2-(1R-trans)]-(1,2-cyclohexanediamine-N,N'') dichloridoplatinu; [SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-N,N') dichloridlatinum(II); MFCD00058826; Oxaliplatin System Suitability (25 mg); [SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-N,N') Dichloridoplatinum(II); cis-dichloro((1R,2R)-cyclohexane-1,2- diamine)platinum(II); [SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-N,N’) Dichloridoplatinum(II); [SP-4-2-(1R-trans)]-（1,2-Cyclohexanediamine-N,N’）dichloridlatinum(Ⅱ); Nsc265460; Caprylic Acid Impurity 26; Platinum, dichloro(1,2-cyclohexanediamine-N,N')-, [sp-4-2-(1R-trans)]; Cis-Dichloro-(1R)-trans-1,2-cyclohexanediamine platinum(Ⅱ); Nsc

物化性质

• 沸点: 193.6ºC at 760mmHg
• 熔点: >256°C (dec.)
• 分子式: C₆H₁₄Cl₂N₂Pt
• 分子量: 380.18
• 闪点: 75ºC
• 精确质量: 379.018198
• PSA: 24.06000
• LogP: 2.43950
• 外观性状: 黄色固体
• 储存条件: 2-8°C，干燥，密封

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TP2275980 CHEMICAL NAME : Platinum(II), (cyclohexane-1,2-diammine)dichloro-, (E)-(-)- CAS REGISTRY NUMBER : 61848-66-6 LAST UPDATED : 199410 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C6-H14-Cl2-N2-Pt MOLECULAR WEIGHT : 380.21 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 20530 ug/kg/10W-I TOXIC EFFECTS : Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 41060 ug/kg/10W-I TOXIC EFFECTS : Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors MUTATION DATA TYPE OF TEST : Mutation test systems - not otherwise specified TEST SYSTEM : Bacteria - Bacillus subtilis DOSE/DURATION : 13 umol/L/3H (Continuous) REFERENCE : CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 41,4368,1981

安全

• 危害码 (欧洲): Xn
• 危险品运输编码: 3467.0

合成路线

10025-99-7 20439-47-8 ~96% 61848-66-6

文献：DABUR RESEARCH FOUNDATION Patent: US2008/207935 A1, 2008 ; Location in patent: Page/Page column 7 ;

10025-99-7 1121-22-8 ~% 61848-66-6

文献：Polyhedron, , vol. 65, p. 42 - 47

91897-69-7 ~% 61848-66-6

文献：Inorganic Chemistry, , vol. 27, p. 2826 - 2831

115185-31-4 ~% 61848-66-6 1129294-89-8

文献：Inorganic Chemistry, , vol. 27, p. 2826 - 2831

124442-35-9 16887-00-6 ~% 61848-66-6 945-51-7

文献：Inorganic Chemistry, , vol. 29, p. 397 - 403

124442-33-7 16887-00-6 ~% 61848-66-6 67-68-5

文献：Inorganic Chemistry, , vol. 29, p. 397 - 403

上下游产品

上游产品  6
10025-99-7 20439-47-8 1121-22-8 115185-31-4
16887-00-6 124442-33-7
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61825-94-3