7607-72-9

• 常用中文名：4-氨甲酰-2-(1,3-二氧基-2,3-二氢-1H-异吲哚-2-基)丁酸
• 常用英文名：5-Amino-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-5-oxopentanoic acid
• CAS号：7607-72-9
• 分子式：C₁₃H₁₂N₂O₅
• 分子量：276.24500
• 发布时间：2016-09-06 12:06:24
• 更新时间：2025-09-17 11:24:44

名称

• 中文名: 4-氨甲酰-2-(1,3-二氧基-2,3-二氢-1H-异吲哚-2-基)丁酸
• 英文名: 5-Amino-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-5-oxopentanoic acid
• 中文别名: 2-((4-氨基-1-羧基-4-氧代丁基)氨基甲酰基)苯甲酸; 泊马度胺杂质54; 2-(1,3-二氧代异吲哚啉-2-基)-5-氨基-5-氧代戊酸
• 英文别名: 2H-Isoindole-2-acetic acid, alpha-(3-amino-3-oxopropyl)-1,3-dihydro-1,3-dioxo-, (+-)- (9ci); 2-Phthalimidoglutamic acid; 2-(1,3-dioxobenzo[c]azolin-2-yl)butanoic acid; Glutamic acid, 2-phthalimido-, (+-); N-Phthaloyl-DL-glutamine; 2H-Isoindole-2-acetic acid, α-(3-amino-3-oxopropyl)-1,3-dihydro-1,3-dioxo; 2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)butanoic acid; (+-)-2-Phthalimido-buttersaeure; alpha-(3-Amino-3-oxopropyl)-1,3-dihydro-1,3-dioxo-2H-isoindole-2-acetic acid; N-phthalyl-(RS)-amino butyric acid; Glutamic acid, 2-phthalimido-, DL- (8ci); N-phthalyl-glutamine; Phenyl-phthalimido-essigsaeure; 2-((4-Amino-1-cboxy-4-oxobutyl)cbamoyl)benzoic acid; N-Phthalyl-DL-glutamine; N-Phthalyl-D,L-glutamine; 2-(1,3-dioxoisoindolin-2-yl)butanoic acid; 2-phthalimidoglutaramic acid; 2-phthalimido-2-phenylacetic acid; Pomalidomide Impurity 54; N2,N2-phthaloyl-DL-glutamine; N-phthalyl-(RS)-phenylglycine; N-phtaloyl-glutamine; N2,N2-Phthaloyl-DL-glutamin; phenyl-phthalimido-acetic acid; 5-Amino-2-(1,3-dioxoisoindolin-2-yl)-5-oxopentanoic Acid; N-phthaloyl phenylglycine; (+-)-2-phthalimido-butyric acid; N-phthalyl phenylglycine acid; N-alpha-Phthaloyl-DL-glutamine

物化性质

• 密度: 1.508g/cm3
• 沸点: 599.3ºC at 760mmHg
• 分子式: C₁₃H₁₂N₂O₅
• 分子量: 276.24500
• 闪点: 316.3ºC
• 精确质量: 276.07500
• PSA: 118.76000
• LogP: 1.08890

合成路线

3343-28-0 ~% 7607-72-9

文献：King; Kidd Journal of the Chemical Society, 1949 , p. 3315,3318

85-44-9 56-85-9 ~% 7607-72-9

文献：Antibioticos S.p.A. Patent: EP1602654 A1, 2005 ; Location in patent: Page/Page column 4/5-6 ;

56-85-9 88-95-9 ~% 7607-72-9

文献：Antibioticos S.p.A. Patent: EP1602654 A1, 2005 ; Location in patent: Page/Page column 5/7 ;

56-85-9 22509-74-6 ~% 7607-72-9

文献：Nakamura, Takanori; Noguchi, Tomomi; Miyachi, Hiroyuki; Hashimoto, Yuichi Chemical and Pharmaceutical Bulletin, 2007 , vol. 55, # 4 p. 651 - 654