毒理学数据:
1.急性毒性 LD50:4500mg/kg(大鼠经口)
2.刺激性 暂无资料
生态学数据:
1.生态毒性 暂无资料
2.生物降解性 暂无资料
3.非生物降解性 暂无资料
4.其他有害作用 该物质对环境有危害,应特别注意对水体的污染。
CHEMICAL IDENTIFICATION
-
RTECS NUMBER :
-
OE5075000
-
CHEMICAL NAME :
-
Lanthanum nitrate
-
CAS REGISTRY NUMBER :
-
10099-59-9
-
LAST UPDATED :
-
199701
-
DATA ITEMS CITED :
-
10
-
MOLECULAR FORMULA :
-
N3-O9.La
-
MOLECULAR WEIGHT :
-
324.94
-
WISWESSER LINE NOTATION :
-
LA N-O3*3
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
-
TYPE OF TEST :
-
LD50 - Lethal dose, 50 percent kill
-
ROUTE OF EXPOSURE :
-
Oral
-
SPECIES OBSERVED :
-
Rodent - rat
-
DOSE/DURATION :
-
4500 mg/kg
-
TOXIC EFFECTS :
-
Details of toxic effects not reported other than lethal dose value
-
TYPE OF TEST :
-
LD50 - Lethal dose, 50 percent kill
-
ROUTE OF EXPOSURE :
-
Intraperitoneal
-
SPECIES OBSERVED :
-
Rodent - rat
-
DOSE/DURATION :
-
450 mg/kg
-
TOXIC EFFECTS :
-
Details of toxic effects not reported other than lethal dose value
-
TYPE OF TEST :
-
LD50 - Lethal dose, 50 percent kill
-
ROUTE OF EXPOSURE :
-
Intraperitoneal
-
SPECIES OBSERVED :
-
Rodent - mouse
-
DOSE/DURATION :
-
309 mg/kg
-
TOXIC EFFECTS :
-
Details of toxic effects not reported other than lethal dose value
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Subcutaneous
-
DOSE :
-
25995 ug/kg
-
SEX/DURATION :
-
male 1 day(s) pre-mating
-
TOXIC EFFECTS :
-
Reproductive - Paternal Effects - testes, epididymis, sperm duct
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Subcutaneous
-
DOSE :
-
25995 ug/kg
-
SEX/DURATION :
-
male 30 day(s) pre-mating
-
TOXIC EFFECTS :
-
Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Paternal Effects - testes, epididymis, sperm duct
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Intratesticular
-
DOSE :
-
25995 ug/kg
-
SEX/DURATION :
-
male 1 day(s) pre-mating
-
TOXIC EFFECTS :
-
Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Paternal Effects - testes, epididymis, sperm duct
MUTATION DATA
-
TYPE OF TEST :
-
Sex chromosome loss and nondisjunction
-
TEST SYSTEM :
-
Yeast - Saccharomyces cerevisiae
-
DOSE/DURATION :
-
33300 ppb
-
REFERENCE :
-
ANYAA9 Annals of the New York Academy of Sciences. (New York Academy of Sciences, 2 E. 63rd St., New York, NY 10021) V.1- 1877- Volume(issue)/page/year: 407,186,1983 *** REVIEWS *** TOXICOLOGY REVIEW JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 54,663,1965 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4766 No. of Facilities: 83 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 331 (estimated) No. of Female Employees: 7 (estimated)
|