869631-11-8

• 常用中文名：O-去乙基坎地沙坦
• 常用英文名：O-Desethyl candesartan cilexetil
• CAS号：869631-11-8
• 分子式：C₃₁H₃₀N₆O₆
• 分子量：582.60600
• 发布时间：2018-06-17 12:08:52
• 更新时间：2026-06-30 18:03:37

名称

• 中文名: O-去乙基坎地沙坦
• 英文名: 1-cyclohexyloxycarbonyloxyethyl 2-oxo-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-1H-benzimidazole-4-carboxylate
• 中文别名: 坎地沙坦乙酯杂质Ⅱ; O-去乙基坎地沙坦西酯; 坎地沙坦酯杂质; CANDESTAN CILEXETIL 杂质 B; 坎地沙坦酯杂质B(坎地沙坦醚); 坎地沙坦西酯相关化合物B; 坎地沙坦 西里西替林 杂质B; 坎地沙坦酯杂质Ⅰ（±）-1-[（环己氧基）羰基氧基]乙基 2-氧代-3-[[2'-（1H-四氮唑-5-基）联苯-4-基]甲基]-2，3-二氢-1H-苯并咪唑-4-羧酸酯; 坎地沙坦西酯杂质B; 坎地沙坦CILEXETIL 杂质B; 坎地沙坦酯杂质B; 坎地沙坦酯杂质Ⅰ(±)-1-[(环己氧基)羰基氧基]乙基 2-氧代-3-[[2'-(1H-四氮唑-5-基)联苯-4-基]甲基]-2,3-二氢-1H-苯并咪唑-4-羧酸酯; 坎地沙坦酯杂质B(去乙基坎地沙坦酯); 坎地沙坦酯杂质2(坎地沙坦酯杂质B); 坎地沙坦酯杂质02; 坎地沙坦杂质 1; 坎地沙坦酯杂质II; 坎地沙坦杂质 II; O-去乙基坎地沙坦酯; 1-((环己氧基)羰基)氧基)乙基3-((2'-(1H-四唑-5-基)-[1,1'-联苯]-4-基)甲基)-2-氧代-2,3-二氢-1H-苯并[D]咪唑-4-羧酸酯 (坎地沙坦酯杂质)
• 英文别名: Candestan Cilexetil Impurity 2 Impurity B); Candestan Impurity II; 1-{[(cyclohexyloxy)carbonyl]oxy}ethyl 3-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-2-oxo-2,3-dihydro-1H-benzimidazole-4-carboxylate; Candestan Cilexetil Impurity Ⅱ; 2,3-Dihydro-2-oxo-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-4-carboxylic Acid 1-[[(Cyclohexyloxy)carbonyl]oxy]ethyl Ester; Candestan Impurity B; Candestan Cilexetil ImpuritⅠ： O-Desethyl Candestan Cilexetil( 2,3-Dihydro-2-oxo-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-4-cboxylic Acid 1-[[(Cyclohexyloxy)carbonyl]oxy]ethyl Ester); 1-(((cyclohexyloxy)carbonyl)oxy)ethyl 3-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-4-cboxylate; Candestan Cilexetil Impurity B (Candestan Cilexetil O-Desethyl Analog); 2,3-Dihydro-2-oxo-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]Methyl]-1H-benziMidazole-4-cboxylic Acid 1-[[(Cyclohexyloxy)carbonyl]oxy]ethyl Ester; Candestan Imp B; Candestan Cilexetil IMpurity B; 1-[[(Cyclohexyloxy)carbonyl]oxy]ethyl 2,3-dihydro-2-oxo-3-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1H-benzimidazole-4-cboxylate; 1-(((Cyclohexyloxy)carbonyl)oxy)ethyl 3-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-4-cboxylate (Candestan cilexetil Impurity); 1-(((cyclohexyloxy)carbonyl)oxy)ethyl 3-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl) -2-oxo-2,3-dihydro-1H-benzo[d]imidazole-4-cboxylate; Candestan Cilexetil Impurity 2(Candestan Cilexetil Impurity B); desethyl-condesartan; 2-oxocandesartan cilexetil; Candestan Cilexetil O-Desethyl Analog; Candestan Cilexetil ImpuritⅠ： O-Desethyl Candestan Cilexetil（ 2,3-Dihydro-2-oxo-3-[[2’-(2H-tetrazol-5-yl)[1,1’-biphenyl]-4-yl]methyl]-1H-benzimidazole-4-cboxylic Acid 1-[[(Cyclohexyloxy)carbonyl]oxy]ethyl Ester）; Candestan Cilexetil Imp. B : (1RS)-1-[[(cyclohexyloxy)carbonyl]oxy]ethyl 2-oxo- 3-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-2,3-dihydro-1H- benzimidazole-4-cboxylate; O-Desethyl Candesartan Cilexetil; Candestan Cilexetil impurity BQ: What is Candestan Cilexetil impurity B Q: What is the CAS Number of Candestan Cilexetil impurity B Q: What is the storage condition of Candestan Cilexetil impurity B Q: What e the applications of Candestan Cilexetil impurity B; O-Desethyl Candestan Cilexetil; Candestan Cilexetil Impurity B (Desethyl Candestan Cilexetil); 1-(Cyclohexyloxycbonyloxy)ethyl 1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl) methyl)-2-hydroxy-1H-benzo[d]imidazole-7-cboxylate; Candestan cilexetil impurity II; (1RS)-1-[[(cyclohexyloxy)carbonyl]oxy]ethyl 2-oxo-3-[[2'-(1H- tetrazol-5-yl)biphenyl-4-yl]methyl]-2,3-dihydro-1H-benzimidazole-4- cboxylate; Candestan Impurity 1; CNS-desethyl; 1H-Benzimidazole-4-cboxylic acid, 2,3-dihydro-2-oxo-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, 1-[[(cyclohexyloxy)carbonyl]oxy]ethyl ester; Candestan Cilexetil Related Compound B (1-(Cyclohexyloxycbonyloxy)ethyl 1-{[2''-(1H- tetrazol-5; Candesartan Cilexetil Impurity 2; (1RS)-1-[[(Cyclohexyloxy)carbonyl]-oxy]ethyl 2-Oxo-3-[[2'-(1H-tetrazol-5-yl-)-biphenyl-4-yl]methyl]; 1-cyclohexyloxycbonyloxyethyl 2-oxo-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-1H-benzimidazole-4-cboxylate; candestan cilexetil impurity1358; desethyl-CNS; UNII-JC6R5VA63B; Candestan Cilexetil Related Compound B

物化性质

• 分子式: C₃₁H₃₀N₆O₆
• 分子量: 582.60600
• 精确质量: 582.22300
• PSA: 154.34000
• LogP: 5.62600

安全

• 危险品运输编码: NONH for all modes of transport

合成路线

170791-09-0 ~% 869631-11-8 145040-37-5

文献：KRKA, D.D. NOVO MESTO Patent: WO2007/42161 A1, 2007 ; Location in patent: Page/Page column 16-17 ;

145040-37-5 ~88% 869631-11-8

文献：Havllcek, Jaroslav; Mandelova, Zuzana; Weisemann, Ruediger; Strelec, Ivo; Placek, Lukas; Radl, Stanislav Collection of Czechoslovak Chemical Communications, 2009 , vol. 74, # 2 p. 347 - 362

170791-09-0 ~70% 869631-11-8

文献：Havllcek, Jaroslav; Mandelova, Zuzana; Weisemann, Ruediger; Strelec, Ivo; Placek, Lukas; Radl, Stanislav Collection of Czechoslovak Chemical Communications, 2009 , vol. 74, # 2 p. 347 - 362

145040-37-5 ~% 869631-11-8 914613-36-8

文献：TEVA PHARMACEUTICAL INDUSTRIES LTD.; TEVA PHARMACEUTICALS USA, INC. Patent: WO2006/122254 A2, 2006 ; Location in patent: Page/Page column 12; 13 ;

145040-37-5 ~% 869631-11-8 914613-35-7 914613-36-8

文献：TEVA PHARMACEUTICAL INDUSTRIES LTD.; TEVA PHARMACEUTICALS USA, INC. Patent: WO2006/122254 A2, 2006 ; Location in patent: Page/Page column 12; 13 ;

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