56073-07-5

• 常用中文名：鼠得克
• 常用英文名：Difenacoum
• CAS号：56073-07-5
• 分子式：C₃₁H₂₄O₃
• 分子量：444.52000
• 相关类别： 分析化学 标准品 农残、兽药及化肥类
• 发布时间：2018-09-04 10:06:14
• 更新时间：2024-01-11 12:12:16
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名称

• 中文名: 鼠得克
• 英文名: difenacoum
• 中文别名: 联苯杀鼠萘; 3-(3-联苯基-1,2,3,4-四氢萘基-1-基)-4-羟基-2H-1-苯并吡喃-2-酮
• 英文别名: Difenacoum; Neosorexa; WBA 8107; Difenacoum [BSI:ISO]; MFCD01632770; Diphenacoum; 4-hydroxy-3-[3-(4-phenylphenyl)-1,2,3,4-tetrahydronaphthalen-1-yl]chromen-2-one; EINECS 259-978-4; 3-(3-[1,1’-biphenyl]-4-yl-1,2,3,4-tetrahydro-1-naphthalenyl)-4-hydroxy-2H-1-benzopyran-2-one; Difenakum [Czech]; 3-[(1RS,3RS; 1RS,3SR)-3-biphenyl-4-yl-1,2,3,4-tetrahydro-1-naphthyl]-4-hydroxycoumarin; 3-[(1Ξ,3Ξ)-3-[1,1’-biphenyl]-4-yl-1,2,3,4-tetrahydronaphthalen-1-yl]-4-hydroxy-2H-1-benzopyran-2-one; Neosorexa PP580; Ratak

物化性质

• 密度: 1.272 g/cm3
• 沸点: 612.8ºC at 760 mmHg
• 熔点: 96-98°C
• 分子式: C₃₁H₂₄O₃
• 分子量: 444.52000
• 闪点: 204.3ºC
• 精确质量: 444.17300
• PSA: 50.44000
• LogP: 7.02750
• 外观性状: 灰白色粉末
• 折射率: 1.676
• 储存条件:

  库房通风低温干燥; 与食品原料分开储运

• 稳定性:

  可燃; 燃烧产生刺激烟雾

• 分子结构:

  1、 摩尔折射率：131.46

  2、 摩尔体积（cm³/mol）：349.4

  3、 等张比容（90.2K）：959.8

  4、 表面张力（dyne/cm）：56.9

  5、 极化率（10^-24cm³）：52.11

• 计算化学:

  1.疏水参数计算参考值（XlogP）:6.9

  2.氢键供体数量:1

  3.氢键受体数量:3

  4.可旋转化学键数量:3

  5.互变异构体数量:3

  6.拓扑分子极性表面积46.5

  7.重原子数量:34

  8.表面电荷:0

  9.复杂度:757

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:2

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

毒性和生态

毒理学数据: 口服-大鼠 LD50: 0.68 毫克/公斤; 口服-小鼠 LD50: 0.80 毫克/公斤 CHEMICAL IDENTIFICATION RTECS NUMBER : GN4934500 CHEMICAL NAME : Coumarin, 3-(3-(4-biphenylyl)-1,2,3,4-tetrahydro-1-naphthyl)-4- hydroxy- CAS REGISTRY NUMBER : 56073-07-5 LAST UPDATED : 199707 DATA ITEMS CITED : 11 MOLECULAR FORMULA : C31-H24-O3 MOLECULAR WEIGHT : 444.55 WISWESSER LINE NOTATION : T66 BOVJ EQ D- GL66&TJ IR DR HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 680 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : MRBUDF MARDI Research Bulletin. (MARDI, Secy., Publication Committee, POB 2301, Kuala Lumpur 01-02, Selangor, Malaysia) V.1- 1973- Volume(issue)/page/year: 12,194,1984 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >50 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,276,1991 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 800 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,276,1991 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 50 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc. of Chemistry, 1983-86 Volume(issue)/page/year: A146,1983 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - cat DOSE/DURATION : 100 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,276,1991 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 2 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc. of Chemistry, 1983-86 Volume(issue)/page/year: A146,1983 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,276,1991 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - pig DOSE/DURATION : 80 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc. of Chemistry, 1983-86 Volume(issue)/page/year: A146,1983 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 50 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,276,1991 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Bird - chicken DOSE/DURATION : 50 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : DEVEAA Defense des Vegetaux. (Federation Nationale des Groupements de Protection des Cultures, 149, rue de Bercy, 75595 Paris Cedex, 12, France) V.1- 1947- Volume(issue)/page/year: 32,27,1978 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - domestic DOSE/DURATION : 100 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : DEVEAA Defense des Vegetaux. (Federation Nationale des Groupements de Protection des Cultures, 149, rue de Bercy, 75595 Paris Cedex, 12, France) V.1- 1947- Volume(issue)/page/year: 32,27,1978

安全

• 符号: GHS06, GHS08, GHS09
• 信号词: Danger
• 危害声明: H300-H372-H410
• 警示性声明: P264-P273-P301 + P310-P314-P501
• 个人防护装备: dust mask type N95 (US);Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
• 危害码 (欧洲): T+, N
• 风险声明 (欧洲): R28;R48/25;R50/53
• 安全声明 (欧洲): S36/37-S45-S60-S61
• 危险品运输编码: 3027
• 包装等级: I
• 危险类别: 6.1(a)